Zobrazeno 1 - 10
of 19
pro vyhledávání: '"M J Yellin"'
Publikováno v:
Inflammation Research. 52:18-25
Objective: To investigate whether CD40-CD154 interactions on HUVEC can trigger COX-2 synthesis as well as PGE2 and PGI2 secretion in vitro and explore whether the CD40-triggered prostanoids provide costimulatory signals for IL-6 secretion in this cel
Publikováno v:
The Journal of Immunology. 157:3876-3885
We have developed human CD4+ T cell lines from the PBL of normal donors by infection with Herpesvirus saimiri (HVS), to evaluate functional properties of these immortalized lymphocytes. In this report, we characterize two such CD4+ T cell lines, CHCD
Publikováno v:
The Journal of Immunology. 155:3329-3337
The regulation of B cell death plays roles in the selection of Ag-specific B cells in humoral immune responses, controlling B cell homeostasis and perhaps limiting transformation. The present work addresses whether CD95 induces tonsillar B cells to u
Autor:
M J Yellin, J Sinning, L R Covey, W Sherman, J J Lee, E Glickman-Nir, K C Sippel, J Rogers, A M Cleary, M Parker
Publikováno v:
The Journal of Immunology. 153:666-674
Activation-induced cell surface molecules are involved in mediating bidirectional T-B lymphocyte signaling that is important in the induction of T or B lymphocyte effector functions. In this regard, T-BAM/CD40-L is an activation-induced CD4+ T cell s
Publikováno v:
The Journal of Immunology. 150:2478-2486
The HIV envelope glycoprotein gp160 has been previously demonstrated to induce differentiation of normal B lymphocytes into Ig-secreting cells; the response is T cell-dependent, and T cells pretreated with gp160 can support B cell differentiation. Th
Publikováno v:
The Journal of Immunology. 149:3817-3826
In lymphoid follicles, CD4+ T lymphocytes provide contact-dependent stimuli to B cells that are critical for the generation of specific antibody responses in a process termed Th function. The CD4+ T cell-restricted surface activation protein, 5c8 Ag
Publikováno v:
The Journal of Immunology. 144:214-220
CD4 is a cell surface glycoprotein that identifies the subset of human T lymphocytes that induces sIg+ B lymphocytes to differentiate and secrete Ig after intimate T-B cell contact. In the course of studying a recombinant, truncated form of CD4 (rT4)
Publikováno v:
The Journal of biological chemistry. 273(7)
We recently reported that macrophages and fibroblasts secrete a Zn2+-dependent sphingomyelinase (S-SMase), which, like lysosomal SMase, is a product of the acid SMase gene. S-SMase may cause subendothelial retention and aggregation of lipoproteins du
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(9)
We have developed human CD4+ T cell lines from the PBL of normal donors by infection with Herpesvirus saimiri (HVS), to evaluate functional properties of these immortalized lymphocytes. In this report, we characterize two such CD4+ T cell lines, CHCD
Autor:
J Brett, David M. Stern, M J Yellin, A Matsushima, David Baum, Leonard Chess, Matthias Szabolcs
Publikováno v:
The Journal of Experimental Medicine
CD40 is expressed on a variety of cells, including B cells, monocytes, dendritic cells, and fibroblasts. CD40 interacts with CD40L, a 30-33-kD activation-induced CD4+ T cell surface molecule. CD40L-CD40 interactions are known to play key roles in B c