Zobrazeno 1 - 10
of 28
pro vyhledávání: '"M J Soloski"'
Publikováno v:
Clinical and Experimental Immunology. 151:130-138
SummaryEnvironmental factors such as diet are known to play important roles in inflammatory bowel disease (IBD). Epidemiological studies have indicated that a high-fat diet is a risk factor for IBD. In addition, the balance between effector T cells (
Publikováno v:
The Journal of Immunology. 158:2183-2191
One of the hallmarks of class I(A) molecules is their ability to bind and present a wide array of peptides to CD8 T cells. This diversity is consistent with their ability to restrict a variety of pathogenic peptide epitopes as well as elicit strong t
Autor:
R F Siliciano, M J Soloski
Publikováno v:
The Journal of Immunology. 155:2-5
Publikováno v:
The Journal of Immunology. 151:2928-2942
T lymphocytes are activated upon binding of their Ag receptors to a complex of Ag-derived peptides and MHC class I or class II molecules expressed on the surface of APC. It is now well established that APC degrade exogenous Ag in acidic endosomal com
Autor:
B, Pérarnau, M F, Saron, B, Reina San Martin, N, Bervas, H, Ong, M J, Soloski, A G, Smith, J M, Ure, J E, Gairin, F A, Lemonnier
Publikováno v:
European journal of immunology. 29(4)
Single H2Kb, H2Db and double H2KbDb homozygous knockout (KO) mice were generated and their peripheral CD8+ T cell repertoires compared to that of C57BL/6 (B6) mice. Limited (10-20%, H2Db), substantial (30-50%, H2Kb) and profound (90%, H2KbDb) reducti
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(9)
Despite being a major group of intracellular pathogens, the role of class I-restricted T cells in the clearance of Gram-negative bacteria is not resolved. Using a murine typhoid model, a role for class I-restricted T cells in the immune response to t
Publikováno v:
Cancer research. 58(20)
Cytotoxic T Cells (CTLs) can exhibit considerable antitumor activity. Thus far, the characterized tumor peptide antigens recognized by CTLs are all presented by classical MHC class Ia molecules [human lymphocyte antigen A (HLA-A), HLA-B, and HLA-C in
Publikováno v:
Immunology. 94(1)
Enhanced major histocompatibility complex (MHC) class I expression is a prominent early feature of pancreatic beta-cell pathology in autoimmune diabetes. The number and nature of class I MHC loci expressed by beta cells are generally undefined and po
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(5)
One of the hallmarks of class I(A) molecules is their ability to bind and present a wide array of peptides to CD8 T cells. This diversity is consistent with their ability to restrict a variety of pathogenic peptide epitopes as well as elicit strong t
Autor:
R F, Siliciano, M J, Soloski
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(1)