Zobrazeno 1 - 10
of 18
pro vyhledávání: '"M J Sheehan"'
Publikováno v:
Insectes Sociaux.
Autor:
Peter R. Butchers, Nicola Bevan, Rick P. C. Cousins, Jill Coates, Valerie S. Morrison, David J. Wilson, M J Sheehan, Emma V. Edgar, Julian James GlaxoSmithKline Reeves
Publikováno v:
European Journal of Pharmacology. 564:219-225
The pharmacological properties of the novel ligand, (2 R ,3 R ,4 S ,5 R )-2-(6-amino-2-{[(1 S )-2-hydroxy-1-(phenylmethyl)ethyl]amino}-9 H -purin-9-yl)-5-(2-ethyl-2 H -tetrazol-5-yl)tetrahydro-3,4-furandiol ( I ), at the human adenosine receptors wer
Autor:
C. Bountra, M J Sheehan, David J. Spalding, Alan Naylor, Paul John Beswick, C.D. Eldred, Sue D. Collins, R.P.C. Cousins, Nick M. Clayton
Publikováno v:
Medicinal Chemistry Research. 13:88-98
Publikováno v:
Drug Development Research. 39:413-425
Blood glucose concentration is a signal for the endocrine pancreas to release insulin or glucagon. Insulin lowers the level of glucose by inhibiting the hepatic glucose production and stimulating glucose utilization by skeletal muscles and adipocytes
Autor:
B. Rosen-Sheidley, C. J. Pouchet, George Chong, M. J. Sheehan, G. Schneider, Marc Tischkowitz, William D. Foulkes, Nora Wong
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 20(4)
Background: MMRpro, prediction of mutations in MLH1 and MLH2 (PREMM1,2) and MMRpredict are models which were developed to predict the probability that an individual carries a Lynch syndrome-causing mutation. Each model utilizes data from personal and
Publikováno v:
Psychopharmacology. 105:204-208
Direct injections of muscimol into the ventral tegmental area (VTA) or substantia nigra zona reticulata (SNR) have been used to selectively stimulate the mesolimbic and nigro-striatal dopamine pathways respectively. Such injections induced locomotor
Publikováno v:
British journal of pharmacology. 122(3)
1. The purpose of this study was to develop and validate an integrated pharmacokinetic-pharmacodynamic model for the anti-lipolytic effects of the adenosine A1-receptor agonist N6-(p-sulphophenyl)adenosine (SPA). Tissue selectivity of SPA was investi
Publikováno v:
British journal of pharmacology. 113(4)
1. The effects of a range of adenosine receptor-selective ligands on body temperature were investigated following intracerebroventricular (i.c.v.) and intraperitoneal (i.p.) injection in conscious mice. The compounds tested were the non-selective ade
Autor:
D R Bull, M J Sheehan
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 343(3)
Fast cyclic voltammetry has been used to measure electrically evoked dopamine overflow from slices of rat nucleus accumbens in vitro. The substance detected was shown voltammetrically and biochemically to be dopamine of neuronal origin. Enough dopami
Autor:
N. R. Oakley, M. J. Sheehan
Publikováno v:
Animal Models in Psychopharmacology ISBN: 9783034864213
Mesolimbic and nigro-striatal dopamine systems were activated by injections of muscimol into the VTA and SNR respectively. The behavioural patterns produced (LMA, sniffing, rearing and grooming) were the same in each case. Clozapine, but not haloperi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c509617ca9fc3f7e5d681d4bad1a5b1d
https://doi.org/10.1007/978-3-0348-6419-0_27
https://doi.org/10.1007/978-3-0348-6419-0_27