Zobrazeno 1 - 10
of 121
pro vyhledávání: '"M J Osborn"'
Autor:
M. J. Osborn
Publikováno v:
Annual Review of Microbiology. 73:1-15
Mary Osborn was a native Californian. She was an undergraduate at the University of California, Berkeley, where she worked in the laboratory of I.L. Chaikoff. She received her PhD at the University of Washington, where her work on the role of folic a
Autor:
M. J. Osborn, Lawrence Rothfield
Publikováno v:
Current Opinion in Microbiology. 10:606-610
The rigid cell wall peptidoglycan (murein) is a single giant macromolecule whose shape determines the shape of the bacterial cell. Insight into morphogenetic mechanism(s) responsible for determining the shape of the murein sacculus itself has begun t
Publikováno v:
Journal of Bacteriology. 173:3128-3133
The uncoupler 2,4-dinitrophenol prevents in vivo synthesis of O antigen in Salmonella typhimurium by inhibiting the first reaction of the pathway, formation of galactosyl-pyrophosphoryl-undecaprenol. Inhibition was observed only in intact cells; dini
Autor:
M. J. Osborn, B C McGrath
Publikováno v:
Journal of Bacteriology. 173:649-654
Previous immunoelectron microscopic studies have shown that both the final intermediate in O-antigen synthesis, undecaprenol-linked O polymer, and newly synthesized O-antigenic lipopolysaccharide are localized to the periplasmic face of the inner mem
Autor:
M. J. Osborn, F.M. Huennekens
Publikováno v:
Advances in Enzymology and Related Areas of Molecular Biology, Volume 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f31faa1b377d48df21f825dcdc4a85c
https://doi.org/10.1002/9780470122662.ch8
https://doi.org/10.1002/9780470122662.ch8
Autor:
M. J. Osborn, B C McGrath
The uncoupler 2,4-dinitrophenol blocks the final step of lipopolysaccharide assembly--transfer of O antigen from undecaprenyl pyrophosphate to core lipopolysaccharide--in intact Salmonella typhimurium but not in isolated membrane fractions. The O-ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5ca3e1185057eb6cc3d2ff63399ab4
https://europepmc.org/articles/PMC207907/
https://europepmc.org/articles/PMC207907/
Publikováno v:
Journal of medical genetics. 28(4)
The phenylalanine hydroxylase gene locus has been studied in 35 independent phenylketonuric families in the south-west of England using RFLP haplotype patterns and allele specific oligonucleotide probes. Haplotype 3 was the most common pattern on mut
Autor:
R Primavesi, A L Meredith, J B Holton, M J Osborn, L. A. Tyfield, Peter S. Harper, T L Chambers
We describe a family in which four subjects in two generations have a disorder of phenylalanine metabolism. Two first cousins had different biochemical presentations in the neonatal period. The older child was thought to have a more severe form of ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c855308b90941c94c4df45d79aa8ccd0
https://europepmc.org/articles/PMC1017218/
https://europepmc.org/articles/PMC1017218/
Publikováno v:
Journal of Biological Chemistry. 260:14965-14970
Energy inhibitors block translocation of pulse-labeled core lipopolysaccharide to outer membrane under conditions which allow maintenance of constant specific radioactivity of intracellular precursor pools throughout the chase period. Under the condi
Publikováno v:
Journal of Biological Chemistry. 252:4904-4912
We describe here the isolation, purification, and structural characterization of a lipid A precursor synthesized under nonpermissive conditions by a mutant of Salmonella typhimurium conditionally defective in the synthesis of the 3-deoxy-D-mannoctulo