Zobrazeno 1 - 10
of 623
pro vyhledávání: '"M J Novak"'
Autor:
Jeffrey L. Ebersole, Armando Burgos, M. J. Novak, Sreenatha Kirakodu, Janis Gonzalez-Martinez, A.J. Stormberg, Octavio A. Gonzalez, Luis Orraca
Publikováno v:
Immunobiology. 224:196-206
Host-derived pattern recognition receptors (PRRs) are necessary for effective innate immune engagement of pathogens that express microbial-associated molecular patterns (MAMP) ligands for these PRRs. This study used a nonhuman primate model to evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed95fdbd4b6b1265f5a41def2d6bf123
https://doi.org/10.1016/j.imbio.2018.11.007
https://doi.org/10.1016/j.imbio.2018.11.007
Autor:
M. J. Novak, Octavio A. Gonzalez, Sreenatha Kirakodu, Dolph Dawson, Armando Burgos, Arnold J. Stromberg, Luis Orraca, Janis Gonzalez-Martinez, Jeffrey L. Ebersole
Publikováno v:
Journal of periodontal researchREFERENCES. 56(1)
OBJECTIVE We hypothesized that autophagy-related genes will be differentially expressed in periodontitis, suggesting an impaired gingival autophagic response associated with disease. BACKGROUND Autophagy is a cellular physiologic mechanism to maintai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da7efa2c5980577335c282f370bc133
https://pubmed.ncbi.nlm.nih.gov/32776336
https://pubmed.ncbi.nlm.nih.gov/32776336
Autor:
M. J. Novak, Sreenatha Kirakodu, Armando Burgos, L. Orraca, Octavio A. Gonzalez, A. J. Stromberg, Jeffrey L. Ebersole, Janis Gonzalez-Martinez
Publikováno v:
Immunobiology. 223:279-287
Host-bacterial interactions at mucosal surfaces require recognition of the bacteria by host cells enabling targeted responses to maintain tissue homeostasis. It is now well recognized that an array of host-derived pattern recognition receptors (PRRs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fed4b0120971ad098ce18dd9ea59a9
https://doi.org/10.1016/j.imbio.2017.10.034
https://doi.org/10.1016/j.imbio.2017.10.034
Publikováno v:
Advances in experimental medicine and biology. 1197
Epithelial cells and functions of the epithelium are critical to the health of the oral cavity. We used a nonhuman primate model to profile the transcriptome of gingival tissues in health across the lifespan and hypothesized that in older animals, ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12059f548b19dfb20789d92fdfaca071
https://pubmed.ncbi.nlm.nih.gov/31732940
https://pubmed.ncbi.nlm.nih.gov/31732940
Autor:
Octavio A. Gonzalez, Shu Shen, M. J. Novak, Sreenatha Kirakodu, C.R. Exposto, J. L. Ebersole, Janis Gonzalez-Martinez, Luis Orraca, Arnold J. Stromberg
Publikováno v:
Molecular Oral Microbiology. 31:18-32
The molecular changes underlying the higher risk of chronic inflammatory disorders during aging remain incompletely understood. Molecular variations in the innate immune response related to recognition and interaction with microbes at mucosal surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368d74566c993eecb13862eb447e1a69
https://doi.org/10.1111/omi.12121
https://doi.org/10.1111/omi.12121
Autor:
M. J. Novak, Sreenatha Kirakodu, Radhakrishnan Nagarajan, J. L. Ebersole, Luis Orraca, Octavio A. Gonzalez, Janis Gonzalez-Martinez
Publikováno v:
Journal of Periodontal Research. 51:152-163
Background and Objective Young/adolescent humans harbor many microorganisms associated with periodontal disease in adults and show substantial gingival inflammatory responses. However, younger individuals do not demonstrate the soft- and hard-tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88a093eff64e6e5ba3e34cede28748b
https://doi.org/10.1111/jre.12293
https://doi.org/10.1111/jre.12293
Autor:
Jeffrey L. Ebersole, Anastasia Kozal, Melween I. Martínez, Yelena Alimova, M. J. Novak, Sreenatha Kirakodu, Luis Orraca, Octavio A. Gonzalez, Arnold J. Stromberg, Janis Gonzalez-Martinez, Ahmad Al-Attar
Publikováno v:
Mucosal immunology
P. gingivalis (Pg) is an oral pathogen with the ability to induce oral dysbiosis and periodontal disease. Nevertheless, the mechanisms by which mucosal responses to the oral microbiota in the presence of specific pathogens such as Pg could abrogate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc395db86c3ec9fd1a148ca993b0f94
https://pubmed.ncbi.nlm.nih.gov/30796336
https://pubmed.ncbi.nlm.nih.gov/30796336
Autor:
Mary Kay Rayens, Debra K. Moser, Misook L. Chung, Alison L. Bailey, Terry A. Lennie, Yevgeniya Gokun, Amanda T. Wiggins, Baretta R. Casey, M. J. Novak, Gia Mudd-Martin, Martha J Biddle
Publikováno v:
The Journal of Rural Health. 31:206-216
Purpose In rural communities that experience high rates of cardiovascular disease (CVD) morbidity and mortality, family history education may enhance risk awareness and support engagement in healthy behaviors but could also engender fatalism. This st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c32d6f8bf2284bd64345480bd82b6fdc
https://doi.org/10.1111/jrh.12094
https://doi.org/10.1111/jrh.12094
Autor:
Luis Orraca, Shu Shen, M. J. Novak, Sreenatha Kirakodu, Armando Burgos, Octavio A. Gonzalez, Arnold J. Stromberg, Jeffrey L. Ebersole, Janis Gonzalez-Martinez
Publikováno v:
Journal of Clinical Periodontology. 41:853-861
Aim Variations in the expression of cytokines during the progression of periodontitis remain ill-defined. We evaluated the expression of 19 cytokine genes related to T-cell phenotype/function during initiation, progression and resolution of periodont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3d2882bce27302c7e33a2a92dda9cb
https://doi.org/10.1111/jcpe.12286
https://doi.org/10.1111/jcpe.12286
Autor:
Alison L. Bailey, Nicolaos Christodoulides, Richard J. Kryscio, Charles L. Campbell, John T. McDevitt, Xiuhua Ding, Beate G. Rose, Pierre N. Floriano, Denis F. Kinane, J. L. Ebersole, M. J. Novak, Joseph D. Foley, Craig S. Miller
Publikováno v:
Journal of Dental Research. 93:72S-79S
The comparative utility of serum and saliva as diagnostic fluids for identifying biomarkers of acute myocardial infarction (AMI) was investigated. The goal was to determine if salivary biomarkers could facilitate a screening diagnosis of AMI, especia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f1b37c9f0cad962aac9ff622ffee02
https://doi.org/10.1177/0022034514537522
https://doi.org/10.1177/0022034514537522