Zobrazeno 1 - 10
of 24
pro vyhledávání: '"M J Mellies"'
Autor:
M E, McGovern, M J, Mellies
Publikováno v:
Clinical therapeutics. 15(1)
Pravastatin is a new lipid-lowering drug belonging to the class of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase inhibitors. Since 1986, more than 15,000 patients have received pravastatin in sponsored clinical research trials with more than 21,
Autor:
D B, Hunninghake, M J, Mellies, A C, Goldberg, P T, Kuo, J B, Kostis, H G, Schrott, W, Insull, H Y, Pan
Publikováno v:
Atherosclerosis. 85(2-3)
This 8-week multicenter, placebo-controlled trial compared the efficacy and safety of the HMG-CoA reductase inhibitor, pravastatin, when administered either as single doses of 40 mg in the morning (AM) or evening (PM) or 20 mg twice daily (bid) in 19
Autor:
D B, Hunninghake, R H, Knopp, G, Schonfeld, A C, Goldberg, W V, Brown, E J, Schaefer, S, Margolis, A S, Dobs, M J, Mellies, W, Insull
Publikováno v:
Atherosclerosis. 85(1)
This multicenter, double-blind, placebo-controlled, dose-response study was conducted in patients with primary hypercholesterolemia to examine the effects of pravastatin, a selective inhibitor of HMG-CoA reductase, on plasma lipids and lipoproteins.
Autor:
C.J. Glueck, C. McMillin, S. McNeely, T.T. Ishikawa, M J Mellies, P.S. Gartside, P.M. Steiner
Publikováno v:
Metabolism. 27:89-96
Ten chlorinated hydrocarbons (tetradifon, Chlorobenzilate, Kepone, lindane, Kelthane, toxaphene, dieldrin, hexachlorobenzene, dienochlor, and Aroclor 1254; see below) were evaluated in rats to assess agents which might selectively elevate high-densit
Autor:
J D Taulbee, G E Lamkin, Ronald J. Jandacek, A Gouge, P King, M J Mellies, Charles J. Glueck, S Goldman, M B Tewksbury, D Boggs, Reginald C. Tsang, L Baehler
Publikováno v:
The American journal of clinical nutrition. 37(3)
Sucrose polyester (SPE) was studied in a double-blind, placebo-controlled trial in 91 outpatients with primary hypercholesterolemia. All patients maintained an isocaloric diet with cholesterol intake of 400 mg/day and a polyunsaturated to saturated f
Publikováno v:
Pediatrics. 78(2)
Our specific aim was to examine the efficacy and safety of long-term cholesterol-lowering diet and bile acid-binding resin therapy in 73 children heterozygous for familial hypercholesterolemia (FH). We prospectively followed accretion of height and w
Autor:
C J, Glueck, R, Larsen, L, Glatfelter, D, Boggs, K, Burton, C, Smith, K, Kelly, M J, Mellies, P, Khoury, J A, Morrison
Publikováno v:
Current concepts in nutrition. 10
Autor:
C J, Glueck, M J, Mellies, L, Srivastava, H C, Knowles, R W, Fallat, R C, Tsang, S, Wacholder, C R, Buncher
Publikováno v:
Pediatric research. 11(1 Pt 1)
Sixteen children with familial hypertriglyceridemia were studied to determine whether there were any distinctive insulintriglycerid-obesity relationships in pediatric familial hypertriglyceridemia. Eleven of 16 children had calculated fat mass greate
Publikováno v:
Advances in experimental medicine and biology. 82
Publikováno v:
The Journal of laboratory and clinical medicine. 88(6)
Relationships between aortic tissue phytosterols and cholesterol in five adults, five infants, two neonates, and one 30 week abortus were studied. In the normal aortic tissue of the abortus and two neonates, tissue cholesterol levels were 0.67, 0.08,