Zobrazeno 1 - 10
of 213
pro vyhledávání: '"M J Langman"'
Autor:
J, Beresford, D G, Colin-Jones, A C, Flind, M J, Langman, D H, Lawson, R F, Logan, K R, Paterson, M P, Vessey
Publikováno v:
Pharmacoepidemiology and drug safety. 7(5)
The pattern of mortality after 15 years of observation is reported among almost 10,000 patients who were taking cimetidine when they were first recruited between 1977 and 1980. Many took the drug for a number of years, some switching to other antisec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a6dbf4f434bc44631d399222fc9d015
https://pubmed.ncbi.nlm.nih.gov/15073978
https://pubmed.ncbi.nlm.nih.gov/15073978
Publikováno v:
British Journal of Cancer
Cimetidine is thought to inhibit suppressor T-lymphocyte function and preliminary evidence from a randomized trial indicated that it might prolong survival for patients with operable and inoperable gastric cancer. The British Stomach Cancer Group con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce55bd7132b9ed308abcc5a2f23f669b
https://pubmed.ncbi.nlm.nih.gov/10604733
https://pubmed.ncbi.nlm.nih.gov/10604733
Autor:
M J, Langman
Publikováno v:
Italian journal of gastroenterology and hepatology. 31
Conventional non steroidal anti-inflammatory drugs (NSAIDs) are probably responsible for a fifth to a quarter of cases of peptic ulcer bleeding, and for the same proportion of deaths. Predisposing factors include age, due probably to underlying susce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::536539f32d9d57550c8fb73b21d97f3c
https://pubmed.ncbi.nlm.nih.gov/10379462
https://pubmed.ncbi.nlm.nih.gov/10379462
Publikováno v:
The Journal of pathology. 184(2)
Since there is a preponderance of large bowel cancer in males, both in humans and in experimental models, and hormone replacement therapy is protective, a role for sex steroid hormones in the pathogenesis of this neoplasm seems likely. Evidence of fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6078661469b16693ef865f149659d20e
https://pubmed.ncbi.nlm.nih.gov/9602706
https://pubmed.ncbi.nlm.nih.gov/9602706
Publikováno v:
The British journal of surgery. 84(8)
Previous studies have not been able to demonstrate convincingly whether the human pancreas expresses oestrogen receptor and whether there is any benefit from antioestrogen therapy in advanced pancreatic cancer.Oestrogen receptor expression was assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cee350828ebf55f0249515d0e4bbc10
https://pubmed.ncbi.nlm.nih.gov/9278646
https://pubmed.ncbi.nlm.nih.gov/9278646
Publikováno v:
Cancer research. 56(3)
1 alpha,25-Dihydroxyvitamin D3 [1,25(OH)2D3] exerts antiproliferative actions in colorectal cancer, but their underlying molecular mechanisms have not been determined. 1,25(OH)2D3 regulates target gene transcription via a specific nuclear vitamin D r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::433beb6914eb793d428165e6feabbb86
https://pubmed.ncbi.nlm.nih.gov/8564982
https://pubmed.ncbi.nlm.nih.gov/8564982
Publikováno v:
Anticancer research. 14(3A)
Epidemiological and experimental evidence support a role for sex steroid hormones in colorectal cancer. The aims of this study were to determine expression of oestrogen receptor in adenoma derived and carcinoma derived colonic epithelial cell lines,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98dfa541037bf4e992e59b673215e6e5
https://pubmed.ncbi.nlm.nih.gov/8074447
https://pubmed.ncbi.nlm.nih.gov/8074447
Autor:
M J, Langman
Publikováno v:
Hepato-gastroenterology. 39
Non-steroidal anti-inflammatory drugs have been clearly shown to increase the chances of peptic ulcer and its complications. Risk factors associated with this propensity are as yet poorly and inconsistently defined. Clinicians have long accepted that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35573b96ecece2f92016777705babbde
https://pubmed.ncbi.nlm.nih.gov/1577395
https://pubmed.ncbi.nlm.nih.gov/1577395
Publikováno v:
The Quarterly journal of medicine. 78(285)
The long-term effects of cimetidine on the occurrence of gastric and oesophageal cancer were assessed in a prospective cohort study of 9928 patients who had been prescribed cimetidine. They were first identified between 1978 and 1980, and cancer regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac6975fcb8cbe794b085ec750dd86c14
https://pubmed.ncbi.nlm.nih.gov/1670060
https://pubmed.ncbi.nlm.nih.gov/1670060