Mitochondrial Dysfunction Plays a Relevant Role in Pathophysiology of Peritoneal Membrane Damage Induced by Peritoneal Dialysis

Autor: M J López-Armada, Tamara Ferreiro-Hermida, Teresa Pérez-López, Mirian López-Pardo, Olalla Ramil-Gómez, Jennifer A Fernández-Rodríguez, Miguel Pérez-Fontán, Ana Rodríguez-Carmona

Publikováno v: Antioxidants
Volume 10
Issue 3
RUC. Repositorio da Universidade da Coruña
instname
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
Antioxidants, Vol 10, Iss 447, p 447 (2021)

[Abstract] Preservation of the peritoneal membrane is an essential determinant of the long-term outcome of peritoneal dialysis (PD). Epithelial-to-mesenchymal transition (EMT) plays a central role in the pathogenesis of PD-related peritoneal membrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c3a73c7adaed8f472ee4ae95b07eb0
https://hdl.handle.net/2183/27648

Autophagy Activation by Resveratrol Reduces Severity of Experimental Rheumatoid Arthritis

Autor: Jennifer A Fernández-Rodríguez, M J López-Armada, Ángel Concha, Olalla Ramil-Gómez, Francisco J. Blanco, M. Camacho-Encina, Á. Vela-Anero, Laura Hermida-Carballo, Susana Viñas-Diz, Maylin Almonte-Becerril

Publikováno v: RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
RUC. Repositorio da Universidade da Coruña
instname

Scope Previous work reported that dietary supplementation with resveratrol lowers synovial hyperplasia, inflammatory and oxidative damage in an antigen-induced arthritis (AIA) model. Here, it is investigated whether resveratrol can regulate the abnor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb505c9a9f29b61cdffe8d6255f3238
https://doi.org/10.1002/mnfr.202000377

Fibrin generated in the synovial fluid activates intimal cells from their apical surface: a sequential morphological study in antigen-induced arthritis

Autor: Jesús Egido, M J López-Armada, Olga Sánchez-Pernaute, Raquel Largo, Gabriel Herrero-Beaumont, I Díez-Ortego, Emilio Calvo

Publikováno v: Rheumatology. 42:19-25

Objective Fibrin deposits adhered to the synovial surface are typical of rheumatoid joints. Since fibrin appears to have a role in arthritis perpetuation our aim was to investigate how these deposits are formed and the consequences of their adhesion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f66194375d33b8218b4b11d9875853
https://doi.org/10.1093/rheumatology/keg021

Effects and Interactions of Endothelin-1 and Angiotensin II on Matrix Protein Expression and Synthesis and Mesangial Cell Growth

Autor: Raquel Largo, Jesús Egido, Juan José Plaza, Dulcenombre Gómez-Garre, E González, Mónica Ortego, M J López-Armada, Marta Ruiz-Ortega

Publikováno v: ResearcherID
Scopus-Elsevier

Abstract Mesangial cell growth and accumulation of extracellular matrix proteins constitute key features of progressive glomerular injury. Endothelin-1 (ET-1) and angiotensin II (Ang II), two potent vasoconstrictor agents, evoke a number of similar r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c87d8c22a5421248b37ff9cc148bc48
https://doi.org/10.1161/01.hyp.27.4.885

THU0118 Sequential ep1 and ep4 regulation in a rabbit model of antigen-induced arthritis

Autor: Raquel Largo, R Guerrero, I Díez-Ortego, Gabriel Herrero-Beaumont, Olga Sánchez-Pernaute, Jesús Egido, M J López-Armada, I Palacios

Publikováno v: Speaker abstracts 2001.

Background Prostaglandin E2 (PGE2) exerts its actions through the binding of the high affinity receptors EP. There are 4 isoforms of EP receptors with extracellular domains highly conserved, each coupling different intracellular transduction systems.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b88918a513e2b54f2e959173ef6385c
https://doi.org/10.1136/annrheumdis-2001.995