Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M J Gratian"'
Autophagosome formation is stimulated by VPS34-dependent PI(3)P formation and by alternative VPS34-independent pathways. We recently described that PI(5)P regulates autophagosome biogenesis and rescues autophagy in VPS34-inactivated cells, suggesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5811aa08f50b329e4859ce37ad0af84f
Publikováno v:
Methods in enzymology. 587
Autophagosome formation is stimulated by VPS34-dependent PI(3)P formation and by alternative VPS34-independent pathways. We recently described that PI(5)P regulates autophagosome biogenesis and rescues autophagy in VPS34-inactivated cells, suggesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b53f307a9772a315f6ca990704474cfd
https://pubmed.ncbi.nlm.nih.gov/28253963
https://pubmed.ncbi.nlm.nih.gov/28253963
Publikováno v:
FEBS Journal. 277:3158-3175
Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a proteinase involved in the remodelling of extracellular matrix and the cleavage of a number of substrates. MT1-MMP is synthesized as a zymogen that requires intracellular post-translational clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e23e40a1b8d7081503fdff0a6f0572d
https://doi.org/10.1111/j.1742-4658.2010.07723.x
https://doi.org/10.1111/j.1742-4658.2010.07723.x
Autor:
Patricia J.C. Dopping-Hepenstal, M G Stone, Hong Wan, John A. McGrath, Robin A.J. Eady, M J Gratian
Publikováno v:
Experimental Dermatology. 12:378-388
Hereditary skin disorders resulting from desmosome gene pathology may preferentially involve the palms and soles. Why this is so is not clear. Moreover, even in normal control skin it is unknown whether there are differences in desmosome number, size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4017307212538ac6f9f4e71df12e6dfc
https://doi.org/10.1034/j.1600-0625.2002.120404.x
https://doi.org/10.1034/j.1600-0625.2002.120404.x
Autor:
R. Mallipeddi, Robin A.J. Eady, M J Gratian, K E Harman, Martin M. Black, S. D. Morris, Balbir S. Bhogal, Noritaka Oyama, John A. McGrath, Takashi Hashimoto
Publikováno v:
Clinical and Experimental Dermatology. 27:665-669
We report a 51-year-old man with a 20-year history of chronic plaque psoriasis who developed an autoimmune subepidermal blistering eruption that had clinical features of bullous pemphigoid, erythema multiforme and epidermolysis bullosa acquisita. Inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db63a50c3a3eff6b074d6bbec147da5e
https://doi.org/10.1046/j.1365-2230.2002.01100.x
https://doi.org/10.1046/j.1365-2230.2002.01100.x
Autor:
M J Gratian, Stephen Challacombe, Penelope Shirlaw, K E Harman, Balbir S. Bhogal, Martin M. Black
Publikováno v:
British Journal of Dermatology. 146:684-687
Summary The transition of pemphigus vulgaris (PV) into pemphigus foliaceus (PF) is rare and the immunological changes underlying this event are not well understood. We report a 44-year-old woman who presented with oral and cutaneous erosions typical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b74cbb49d1988931d51d3128dac1cf8
https://doi.org/10.1046/j.1365-2133.2002.04608.x
https://doi.org/10.1046/j.1365-2133.2002.04608.x
Publikováno v:
Clinics in Dermatology. 19:638-641
In the investigation of patients with autoimmune blistering skin diseases, immunogold electron microscopy has proved to be a useful approach in identifying target antigens. Such data are often important in establishing accurate subtyping of an indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4572c81d82da365e268bdb5bd812afa3
https://doi.org/10.1016/s0738-081x(00)00177-2
https://doi.org/10.1016/s0738-081x(00)00177-2
Autor:
Paul T. Seed, Balbir S. Bhogal, K E Harman, Stephen Challacombe, M J Gratian, Martin M. Black
Publikováno v:
British Journal of Dermatology. 144:775-780
Background Pemphigus vulgaris (PV) and foliaceus (PF) are characterized by antibodies to the desmosomal proteins desmoglein 3 (Dsg3) and desmoglein 1 (Dsg1), respectively. Past studies using indirect immunofluorescence (IIF) as a measure of pemphigus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80542867ba5c33fd21a3e0e98456249e
https://doi.org/10.1046/j.1365-2133.2001.04132.x
https://doi.org/10.1046/j.1365-2133.2001.04132.x
Autor:
E.L. Rugg, Celia Moss, E. B. Lane, Nicola X West, Patricia J.C. Dopping-Hepenstal, Nairn Wilson, K Batta, Helen Goodyear, Robin A.J. Eady, M J Gratian
Publikováno v:
British Journal of Dermatology. 143:621-627
Epidermolysis bullosa simplex (EBS) is a blistering skin disease caused in most cases by mis-sense mutations in genes encoding the basal epidermal keratin (K) 5 and K14. The inheritance is usually autosomal dominant and the mutant keratin proteins ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc18450035df5f3a69f1ee8d79a45af7
https://doi.org/10.1111/j.1365-2133.2000.03722.x
https://doi.org/10.1111/j.1365-2133.2000.03722.x
Publikováno v:
British Journal of Dermatology. 143:343-348
Background Pemphigus vulgaris (PV) is characterized by pathogenic autoantibodies to desmoglein (Dsg) 3, but additional antibodies to Dsg1, the pemphigus foliaceus antigen, are detectable in some cases. Objectives To investigate the clinical significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af5e522e9d26b3c70fcf76df0a17e2e
https://doi.org/10.1046/j.1365-2133.2000.03660.x
https://doi.org/10.1046/j.1365-2133.2000.03660.x