Zobrazeno 1 - 10
of 61
pro vyhledávání: '"M J Fritzler"'
Autor:
Anastasiya Muntyanu, Raymond Milan, Elham Rahme, Avery LaChance, Lydia Ouchene, Maxime Cormier, Ivan V. Litvinov, Marie Hudson, Murray Baron, Elena Netchiporouk, the Canadian Scleroderma Research Group, M. Baron, M. Hudson, G. Gyger, J. Pope, M. Larche, N. Khalidi, A. Masetto, E. Sutton, T. S. Rodriguez Reyna, N. Maltez, C. Thorne, P. R. Fortin, A. Ikic, D. Robinson, N. Jones, S. LeClercq, P. Docherty, D. Smith, M. J. Fritzler
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
IntroductionSystemic sclerosis (SSc) is thought to be induced by an environmental trigger in genetically predisposed individuals. This study assessed the demographic and clinical characteristics and disease severity of silica exposed SSc patients.Met
Externí odkaz:
https://doaj.org/article/a85a8b91de25460a9ab959c3169bdf5c
Autor:
M Y, Choi, M J, Fritzler
Publikováno v:
Lupus. 28(11)
Autoantibodies (AA) and antinuclear antibodies (ANA) serve as key diagnostic and classification criteria for systemic lupus erythematosus (SLE). More than 200 different AA have been reported in SLE, although only a handful (20) are considered "mainst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78479f3259ddcf524afa90b5c4ad1625
https://pubmed.ncbi.nlm.nih.gov/31399014
https://pubmed.ncbi.nlm.nih.gov/31399014
Autor:
M. J. Fritzler, R. Goldstein, O. P. Kelly, Caroline Schild-Poulter, A. Shih, R. J. G. Haché, A. Su
Publikováno v:
Rheumatology. 47:165-171
Objective. To analyse the autoimmune response to DNA damage response factors in systemic autoimmune rheumatic disease (SARD) patients and to determine their association with autoantibodies to Ku antigen. Methods. We have screened the serum of 239 pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d28b9f0a9ffc6e047f17ca6afcb7145
https://doi.org/10.1093/rheumatology/kem338
https://doi.org/10.1093/rheumatology/kem338
Autor:
Sehriban, Diab, Nathaniel, Dostrovsky, Marie, Hudson, Solène, Tatibouet, Marvin J, Fritzler, Murray, Baron, Nader, Khalidi, M J, Fritzler
Publikováno v:
The Journal of rheumatology. 41(11)
Objective.To describe the clinical and serological features of systemic sclerosis sine scleroderma (ssSSc) in a multicentered SSc cohort.Methods.Data from 1417 subjects in the Canadian Scleroderma Research Group registry were extracted to identify su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a41eb49a9a737dbef6378162b1fdbb6
https://pubmed.ncbi.nlm.nih.gov/25274885
https://pubmed.ncbi.nlm.nih.gov/25274885
Autor:
L, Martin, M J, Fritzler
Publikováno v:
Canadian family physician Medecin de famille canadien. 36
Certain genetic markers in the major histocompatibility complex have been associated with increased risk of developing ankylosing spondylitis, rheumatoid arthritis, and systemic lupus erythematosus. These markers, however, do not appear in all patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c63e6a558f9bef80792e9a73e5cb4c64
https://pubmed.ncbi.nlm.nih.gov/21234066
https://pubmed.ncbi.nlm.nih.gov/21234066
Publikováno v:
The Journal of Experimental Medicine
Serum autoantibodies from a patient with autoantibodies directed against the Golgi complex were used to screen clones from a HepG2 lambda Zap cDNA library. Three related clones, designated SY2, SY10, and SY11, encoding two distinct polypeptides were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb7e0d4b68fa1b2fa798942b9ce8358
https://doi.org/10.1084/jem.178.1.49
https://doi.org/10.1084/jem.178.1.49
Autor:
M Salazar, M J Fritzler
Publikováno v:
Clinical Microbiology Reviews. 4:256-269
A hallmark of sera from patients with systemic rheumatic diseases is the presence of circulating autoantibodies directed against nuclear antigens. The identification of the antigens binding to these antibodies has provided the cell biologist and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf320dff97efbe3539f4b7f4eaad1b12
https://doi.org/10.1128/cmr.4.3.256
https://doi.org/10.1128/cmr.4.3.256
Publikováno v:
Genes and immunity. 4(1)
Phosphatidylinositol 3-kinase (PI3K) has emerged as a critical component of multiple immune system intracellular signalling pathways. The levels and relative ratios of PI3K products, phosphatidylinositol (3,4) bisphosphate (PI(3,4)P(2)) and phosphati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8ac18cbb2c57abb23ec8579be60b01
https://pubmed.ncbi.nlm.nih.gov/12595903
https://pubmed.ncbi.nlm.nih.gov/12595903
Publikováno v:
The Journal of rheumatology. 27(2)
Autoantibodies to the U3 nucleolar ribonucleoprotein (RNP) fibrillarin occur in some patients with systemic sclerosis (SSc) or other connective tissue diseases and can be induced in certain mouse strains by injections of mercuric chloride, perhaps du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3510938f3f56dd48a2b35024151bc89f
https://pubmed.ncbi.nlm.nih.gov/10685806
https://pubmed.ncbi.nlm.nih.gov/10685806
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 47(6)
We have identified 36 human sera sent for autoantibody analyses that produce a unique vesicular staining pattern of the cytoplasm of tissue culture cells. The purpose of this study was to identify the autoantigens that are recognized by the sera that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d71dcf1ff55aceefed008d55a680f298
https://pubmed.ncbi.nlm.nih.gov/10431486
https://pubmed.ncbi.nlm.nih.gov/10431486