Zobrazeno 1 - 10
of 56
pro vyhledávání: '"M J Crumpton"'
Publikováno v:
The Journal of Immunology. 144:1010-1014
The phosphorylation of the invariant chains associated with the human TCR has been investigated after the stimulation of T lymphocytes with CD2 mAb T11(2) and T11(3), PHA, or phorbol 12,13-dibutyrate. As described previously, stimulation of T cells w
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(9)
The CD7 cluster of mAb identifies a 40-kDa glycopolypeptide that is present on a major subset of human T cells. CD7 Ag mediates an accessory pathway of T cell activation in that cross-linked CD7 mAb are mitogenic, and signals delivered via CD7 Ag sti
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(3)
The phosphorylation of the invariant chains associated with the human TCR has been investigated after the stimulation of T lymphocytes with CD2 mAb T11(2) and T11(3), PHA, or phorbol 12,13-dibutyrate. As described previously, stimulation of T cells w
Autor:
S E, Moss, M J, Crumpton
Publikováno v:
Advances in experimental medicine and biology. 269
Autor:
M. J. Crumpton, John R. Dedman
Publikováno v:
Nature. 345:212-212
Publikováno v:
Journal of Clinical Pathology. 41:121-127
Polyclonal rat antisera, raised against affinity purified CD3 antigen, gave strong immunoenzymatic labelling of T cells in routine paraffin embedded sections, with negligible background staining. The specificity of these reactions was confirmed by st
Publikováno v:
Journal of Biological Chemistry. 260:1927-1936
Two-dimensional polyacrylamide gel analyses of immunoprecipitates of HLA-D region antigens prepared from [35S]methionine-labeled B lymphoblastoid cells revealed a number of invariant polypeptides (Ii and theta) that co-precipitate with the alpha and
Publikováno v:
The Journal of Immunology. 142:1626-1630
An immediate consequence of Ag-specific activation of T cells is phosphorylation of the gamma-subunit of the CD3 gamma-chain. There is good evidence that the kinase that mediates CD3 gamma-chain phosphorylation is protein kinase C (pkC). It has also
Publikováno v:
Journal of Biological Chemistry. 262:10918-10921
The gamma subunit of the human T lymphocyte T3 antigen is rapidly phosphorylated on serine residues in vivo during the initiation of T cell activation by a polyclonal mitogen (Phaseolus vulgaris phytohemagglutinin), an activator of protein kinase C (
Publikováno v:
The Journal of Immunology. 138:3513-3518
Complementary DNA (cDNA) clones encoding the T3 gamma subunit of the mouse T3/T cell antigen receptor complex were isolated from a cDNA library prepared from a cytochrome C-specific, I-E (class II antigen)-restricted murine T cell clone. The cDNA hyb