Zobrazeno 1 - 3
of 3
pro vyhledávání: '"M J Castañon"'
Publikováno v:
The Journal of Cell Biology
Plectin is an intermediate filament (IF) binding protein of exceptionally large size. Its molecular structure, revealed by EM and predicted by its sequence, indicates an NH2-terminal globular domain, a long rodlike central domain, and a globular COOH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2319b6d00868c89cfed22168916d7a
http://europepmc.org/articles/PMC2119566
http://europepmc.org/articles/PMC2119566
Autor:
K Luber, Georg Weitzer, R Hauptmann, Gerhard Wiche, Murray Stewart, C Stratowa, M J Castañon, Bruno Becker
Publikováno v:
The Journal of Cell Biology
We have determined the complete cDNA sequence of rat plectin from a number of well-characterized overlapping lambda gt11 clones. The 4,140-residue predicted amino acid sequence (466,481 D) is consistent with a three-domain structural model in which a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e4ae59d26ee92daa5ab5af1d9b86ba
https://doi.org/10.1083/jcb.114.1.83
https://doi.org/10.1083/jcb.114.1.83
Autor:
C, Stratowa, A, Baum, M J, Castañon, G, Dahmann, F, Himmelsbach, A, Himmler, G, Loeber, T, Metz, R, Schnitzer, F, Solca, W, Spevak, U, Tontsch, T, von Rüden
Publikováno v:
Anti-cancer drug design. 14(5)
Growth factor receptor tyrosine kinases (RTK) have been implicated in tumor growth, metastasis and angiogenesis, and are thus considered promising targets for therapeutic intervention in malignant diseases. We present a novel drug discovery strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71794078fee8f9ff26dcd03db34408d6
https://pubmed.ncbi.nlm.nih.gov/10766294
https://pubmed.ncbi.nlm.nih.gov/10766294