Zobrazeno 1 - 10 of 27 pro vyhledávání: '"M J Browne"'
2
Hydrozoan sperm-specific H2B histone variants stabilize chromatin and block transcription without enhancing chromatin condensation
Autor: J. C. Vilar, M. J. Browne, Andrew Flaus, Uri Frank, F. Febrimarsa, I. Patwal, Sebastian G. Gornik, Anna Török, T. Q. DuBuc, E. Atcheson
Many animals achieve sperm chromatin compaction and stabilisation during spermatogenesis by replacing canonical histones with sperm nuclear basic proteins (SNBPs) such as protamines. A number of animals including hydrozoan cnidarians and echinoid sea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3043a3ff949dad6069e3d8329b27507e
https://doi.org/10.1101/2021.08.30.458175
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3
Employment of 16S rDNA gene sequencing techniques for improved identification of difficult-to-identify bacterial veterinary pathogens
Autor: Jiru Xu, Paul J. Rooney, Colin E. Goldsmith, Anne Loughrey, V. M. J. Browne-Lauwers, Motoo Matsuda, B. Cherie Millar, Yasunori Maeda, J. Stuart Elborn, Peter H. Herold, John E. Moore
Publikováno v: World Journal of Microbiology and Biotechnology. 24:1227-1232
To employ 16S rDNA PCR and automated sequencing techniques to identify a collection of bacterial veterinary pathogens from avian, equine, canine and ovine sources, that have proven difficult to identify, employing conventional cultural techniques. Un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::737aa84066673516a08b2e0fc5ee7d5c
https://doi.org/10.1007/s11274-007-9573-6
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5
Development of a Novel Marker Gene Based Assay System for Detection and Evaluation of Antiviral Agents with Activity against Papillomaviruses
Autor: D. N. Planterose, M. J. Browne, R. M. Perkins, K. May
Publikováno v: Antiviral Chemistry and Chemotherapy. 2:363-370
A novel assay system has been developed in which expression of a human tissue-plasminogen activator (t-PA) gene, carried on a recombinant papillomavirus vector, is used as a marker for the presence of bovine papillomavirus type 1 (BPV-1) within trans
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38d25dde7892c4bffb35b739b8608700
https://doi.org/10.1177/095632029100200605
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6
Cloning and expression of single chain antibody fragments in Escherichia coli and Pichia pastoris
Autor: S. D. Holmes, Pauline M. Cupit, Charles Cunningham, J. A. Whyte, M. J. Browne, Andrew J. Porter, William J. Harris
Publikováno v: Letters in applied microbiology. 29(5)
The potential of recombinant antibody fragments is likely to be fulfilled only if they can be produced routinely at high concentrations. We have compared the ability of Escherichia coli and Pichia pastoris to produce functional recombinant single cha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1364fb56c8f6d826a598836fe2865e5b
https://pubmed.ncbi.nlm.nih.gov/10664964
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7
Asymmetric information and the demand for Medigap insurance
Autor: M J, Browne, H, Doerpinghaus
Publikováno v: Inquiry : a journal of medical care organization, provision and financing. 31(4)
The Medigap insurance market has been characterized as having considerable cross-policy variation in contract design and relatively high premiums vis-a-vis average risk exposure. One explanation for these characteristics is that adverse selection exi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::77f040d7d7998db1a3c697dc8036ce0f
https://pubmed.ncbi.nlm.nih.gov/7821998
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8
The use of active centre acylation to control the pharmacokinetic profile of a recombinant chimaeric plasminogen activator
Autor: S, Wilson, D W, Cronk, I, Dodd, A F, Esmail, S B, Kalindjian, L, McMurdo, M J, Browne, R A, Smith, J H, Robinson
Publikováno v: Thrombosis and haemostasis. 70(6)
Recombinant hybrid plasminogen activators consisting of the "A" chain of plasminogen linked to the "B" chain of t-PA that are inhibited rapidly by plasma protease inhibitors have recently been described (Robinson et al. Circulation 1992; 86: 548-552)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::412929b8330e5baa4d046774f6a240eb
https://pubmed.ncbi.nlm.nih.gov/8165622
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9
A recombinant, chimeric enzyme with a novel mechanism of action leading to greater potency and selectivity than tissue-type plasminogen activator
Autor: Ian B. Dodd, A.F. Esmail, J.E. Carey, S. B. Kalindjian, C. Entwisle, J H Robinson, P. D. Chamberlain, C.G. Chapman, M J Browne, D. W. Cronk
Publikováno v: Circulation. 86(2)
BACKGROUND Early intervention with thrombolytic agents has been shown unequivocally to reduce mortality after acute myocardial infarction. Presently used agents have disadvantages such as short half-life, immunogenicity, hypotension, and bleeding com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928934490922f4d938e7e68dfb23588a
https://pubmed.ncbi.nlm.nih.gov/1638720
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