Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M J Bottomley"'
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-5 (2020)
Abstract Background A number of disease processes can culminate in rapidly progressive glomerulonephritis, including pauci-immune focal segmental necrotising glomerulonephritis, usually seen with positive serum antineutrophil cytoplasmic antibodies (
Externí odkaz:
https://doaj.org/article/7db9f0a0cb564400acb6e95cf339cf8b
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background ANCA-associated vasculitis is a life-threatening, systemic autoimmune disease. There is an increased risk of organ infarction but in many cases this is asymptomatic. We described here the first reported case of PR3 vasculitis pres
Externí odkaz:
https://doaj.org/article/b96f9bd610a040dc91ce30c02813df95
Autor:
S, Pecetta, P, Lo Surdo, M, Tontini, D, Proietti, C, Zambonelli, M J, Bottomley, M, Biagini, F, Berti, P, Costantino, M R, Romano, N, Norais
Publikováno v:
Vaccine. 33:314-320
Glycoconjugate vaccines play an enormous role in preventing infectious diseases. The main carrier proteins used in commercial conjugate vaccines are the non-toxic mutant of diphtheria toxin (CRM197), diphtheria toxoid (DT) and tetanus toxoid (TT). Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070bc782edbc30f3819f08c8e1631eab
https://doi.org/10.1016/j.vaccine.2014.11.026
https://doi.org/10.1016/j.vaccine.2014.11.026
Autor:
Paul C. Driscoll, M. J. Bottomley, John M. Clements, R M Edwards, David I. Stuart, Robert Robinson, Karl Harlos, E Y Jones, T. J. Dudgeon
Publikováno v:
Scopus-Elsevier
The cell-surface glycoprotein vascular cell adhesion molecule-1 (VCAM-1; ref. 1) mediates intercellular adhesion by specific binding to the integrin very-late antigen-4 (VLA-4, alpha 4 beta 1; ref. 3). VCAM-1, with the intercellular adhesion molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399c91577afdfe380aef5ea8dc97be5d
https://doi.org/10.1038/373539a0
https://doi.org/10.1038/373539a0
Publikováno v:
Current Biology. 11(14):1114-1118
Quality control within the endoplasmic reticulum (ER) is thought to be mediated by the interaction of a folding protein with one or several resident ER proteins [1]. Protein disulphide isomerase (PDI) is one such ER resident protein that has been pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9ebfd90d249d35455d703cec1800eb
Publikováno v:
Cytokine. 12:1232-1235
Dysregulated vascular endothelial growth factor (VEGF) expression has been implicated as a major contributor to the development of a number of common disease pathologies. The aim of this study was to establish the extent of genetic variability within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4f6f56e8dff4af1e2c0b180eac7e59
https://doi.org/10.1006/cyto.2000.0692
https://doi.org/10.1006/cyto.2000.0692
Autor:
Marwan Bukhari, Anthony J. Freemont, J. Denton, C. J. Watson, L. Holt, P. E. C. Brenchley, M J Bottomley, N. J. A. Webb
Publikováno v:
Clinical and Experimental Immunology. 119:182-188
SUMMARYThe aims of this study were (i) to determine whether PlGF, VEGF and PlGF/VEGF heterodimers are detected in synovial fluid (SF) and plasma samples from patients with a range of arthropathies; (ii) to describe whether any correlation exists betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88763623253b3a39dbd024345e019d85
https://doi.org/10.1046/j.1365-2249.2000.01097.x
https://doi.org/10.1046/j.1365-2249.2000.01097.x
Autor:
Elaine M. Bailey, M J Bottomley, Steven J. Harper, John Feehally, Peter N. Furness, P. E. C. Brenchley, S Westwell, J. H. Pringle
Publikováno v:
ResearcherID
AIM: To investigate vascular endothelial growth factor (VEGF) mRNA expression in glomerular disease in the context of heavy proteinuria. METHODS: Non-radioisotopic in situ hybridisation was performed using a cocktail of 12 deoxyoligonucleotides compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9482c0eb46695ad365c74cfcb0ae02a8
https://doi.org/10.1136/jcp.52.10.735
https://doi.org/10.1136/jcp.52.10.735
Publikováno v:
Current biology : CB. 11(14)
Quality control within the endoplasmic reticulum (ER) is thought to be mediated by the interaction of a folding protein with one or several resident ER proteins [1]. Protein disulphide isomerase (PDI) is one such ER resident protein that has been pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb45ea86414ea2362a846a355aef3aab
https://pubmed.ncbi.nlm.nih.gov/11509234
https://pubmed.ncbi.nlm.nih.gov/11509234
Publikováno v:
Nature structural biology. 8(7)
The SAND domain is a conserved sequence motif found in a number of nuclear proteins, including the Sp100 family and NUDR. These are thought to play important roles in chromatin-dependent transcriptional regulation and are linked to many diseases. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::876a74ce2da17db7f85f14ddd6734b39
https://pubmed.ncbi.nlm.nih.gov/11427878
https://pubmed.ncbi.nlm.nih.gov/11427878