Zobrazeno 1 - 10
of 47
pro vyhledávání: '"M J Beyak"'
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 5:92-93
Background Anecdotal reports suggest that access to pH/motility testing is problematic in Canada, but to date there is little data documenting this. Aims To assess the volume and accessibility of motility lab testing in Canada. Methods The CNN develo
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 5:4-5
Background Dysphagia is a common referral to gastroenterology with both benign and malignant etiologies. There is a lack of studies regarding its clinical assessment, complications and outcomes in Canada. Aims To evaluate the assessment and outcomes
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 5:52-53
Background Ulcerative Colitis (UC) and Crohn’s Disease (CD) are subtypes of Inflammatory Bowel Disease (IBD) which is a condition with an unclear etiology causing inflammation of the small and large intestine (Public Health Agency of Canada, 2021).
Publikováno v:
J Can Assoc Gastroenterol
Background CVID is the most common type of severe antibody deficiency. Gastrointestinal manifestations affect approximately 20–50% of patients. Boland et al. described in a case series that 2/3 CVID patients were able to achieve clinical and endosc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879c42c9e8ca8d8b3843f20f5d8851d1
https://europepmc.org/articles/PMC7958746/
https://europepmc.org/articles/PMC7958746/
BACKGROUND: We have recently shown that suppressor of cytokine signaling-3 (SOCS3), a negative regulator in leptin signalling, plays a role in vagal hyposensitivity associated with diet-induced obesity and high concentrations of leptin. Diet-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badb801bd3a6c4b75a93961898539185
https://europepmc.org/articles/PMC6507681/
https://europepmc.org/articles/PMC6507681/
BACKGROUND: A number of studies have shown that high fat feeding in the mouse (a commonly used model of diet-induced obesity) results in impaired vagally-mediated satiety responses. Mechanical stimulation of the GI tract is an important stimulus of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0760edfa73224bed5d72eb23ad6f8e23
https://europepmc.org/articles/PMC6508409/
https://europepmc.org/articles/PMC6508409/
BACKGROUND: The orexigenic hormone ghrelin regulates feeding behavior via vagal afferent pathways. The mechanisms by which ghrelin exerts its inhibitory effects on nodose ganglion neurons are largely unknown. There is a evidence that ghrelin caused a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2918fbc915849fe541b0ac94b8e1a453
https://europepmc.org/articles/PMC6508303/
https://europepmc.org/articles/PMC6508303/
BACKGROUND: We have demonstrated that diet-induced obesity impairs vagal afferents and that the effects of high concentrations of leptin on vagal afferents in vitro, mimic the effects of obesity. One of downstream molecules in leptin signaling is pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17bed870b2d620b3fd4481cfdc024dcd
https://europepmc.org/articles/PMC6507739/
https://europepmc.org/articles/PMC6507739/
BACKGROUND: Our previous studies have demonstrated impaired vagal afferent sensitivity to satiety mediators and distention of the gut in high fat fed (HFF) obese mouse iNOS (inducible nitric oxide synthase) knockout mice are protected against high fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7a28d72a37b76588dccec94a4f4656
https://europepmc.org/articles/PMC6507805/
https://europepmc.org/articles/PMC6507805/
Publikováno v:
Neurogastroenterology and Motility. 15:401-407
Nitric oxide (NO) in the brainstem is implicated in the control of swallowing and oesophageal peristalsis. This study examines the role of brainstem NO in the maintenance of lower oesophageal sphincter (LOS) tone, relaxation and contraction. In ureth