Zobrazeno 1 - 10 of 10 pro vyhledávání: '"M J Bamford"'
1
New populations of the black-flanked rock-wallaby (Petrogale lateralis) from the Little Sandy Desert and Murchison, Western Australia
Autor: M. J. Bamford, Judy Dunlop, Nicole White, J. M. Turpin
Publikováno v: Australian Mammalogy. 40:234
During two independent fauna surveys, rock-wallaby (Petrogale) scats were recorded from caves located outside the current known Petrogale distribution. Scats collected from Desert Queen Baths (Little Sandy Desert, Western Australia, 2012), and the Ba
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9c4b090083a21e44f12ac2d06d544bb
https://doi.org/10.1071/am14043
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2
The Squalestatins: Synthesis and Biological Activity of Some C3-Modified Analogs; Replacement of a Carboxylic Acid or Methyl Ester with an Isoelectronic Heterocyclic Functionality
Autor: B. E. Kirk, A P Craven, Michael George Lester, D Green, Panayiotis Alexandrou Procopiou, Chuen Chan, R A Henson, Brian Dymock, M J Bamford, Michael A. Snowden
Publikováno v: Journal of Medicinal Chemistry. 38:3502-3513
A series of squalestatins modified at the C3-position with a heterocyclic functionality was prepared and evaluated in vitro as inhibitors of squalene synthase (SQS). Structure-activity relationships for compounds with the 4,6-dimethyloctenoate at C6(
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c42ce4af3af3af4a88d3b5cb7ee842f
https://doi.org/10.1021/jm00018a010
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3
The Squalestatins: Novel Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in vivo Evaluation of C1-Modified Analogs
Autor: P A, Procopiou, E J, Bailey, M J, Bamford, A P, Craven, B W, Dymock, J G, Houston, J L, Hutson, B E, Kirk, A D, McCarthy, M, Sareen
Publikováno v: Journal of Medicinal Chemistry. 37:3274-3281
Squalestatin analogues modified in the C1 side chain were prepared and evaluated for their ability to inhibit rat liver microsomal and Candida squalene synthase (SQS) in vitro. While maintaining the 4,6-dimethyloctenoate or 4,6-dimethyloctanoate este
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff321dc4c4e3be2a2b2e341edc448e6a
https://doi.org/10.1021/jm00046a011
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4
Synthesis and Structure Activity Relationships of a Series of Penicillin-Derived Pseudosymmetric Inhibitors of HIV-1 Proteinase
Autor: Richard Storer, M. J. Bamford, David Cedric Humber, Richard C. Bethell, P. G. Wyatt, N. Cammack, Gordon G. Weingarten, D. C. Orr
Publikováno v: Antiviral Chemistry and Chemotherapy. 5:197-200
The synthesis from penicillin G of a series of potent pseudosymmetric inhibitors 11 a-k of HIV-1 proteinase is described. The 2-pyridyl substituted compounds 11a and 11j showed improved antiviral activity compared to their C2-symmetric counterparts 3
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0494c63129745f5e8213250692aa7784
https://doi.org/10.1177/095632029400500311
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5
ChemInform Abstract: Synthesis and Antiviral Activity of 3′-Deoxy-3′-C-hydroxymethyl Nucleosides
Autor: Paul L. Coe, Richard T. Walker, M. J. Bamford
Publikováno v: ChemInform. 22
A series of 3'-branched-chain sugar nucleosides, in particular 3'-deoxy-3'-C-hydroxmethyl nucleosides, have been synthesized and evaluated as antiviral agents. Reaction of 1-(2,3-epoxy-5-O-trityl-beta-D-lyxo-pentofuranosyl) derivatives 12 and 13, of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5a02d5aa708281b95192df298d3e17e
https://doi.org/10.1002/chin.199108326
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6
ChemInform Abstract: Synthesis and Antiviral Activity of Some 3′-C-Difluoromethyl and 3′- Deoxy-3′-C-fluoromethyl Nucleosides
Autor: Paul L. Coe, M. J. Bamford, Richard T. Walker
Publikováno v: ChemInform. 22
The synthesis and antiviral activity of a number of 3'-C-difluoromethyl and 3'-deoxy-3'-C-fluoromethyl nucleosides are reported. The 3'-C-difluoromethyl nucleosides 26a and 26b were obtained by treatment of the corresponding 2',5'-di-O-protected-3'-C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91ef73f187816a7c7701f596d39da3f6
https://doi.org/10.1002/chin.199108325
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9
Synthesis and antiviral activity of 3'-deoxy-3'-C-hydroxymethyl nucleosides
Autor: Richard T. Walker, Paul L. Coe, M. J. Bamford
Publikováno v: Journal of medicinal chemistry. 33(9)
A series of 3'-branched-chain sugar nucleosides, in particular 3'-deoxy-3'-C-hydroxmethyl nucleosides, have been synthesized and evaluated as antiviral agents. Reaction of 1-(2,3-epoxy-5-O-trityl-beta-D-lyxo-pentofuranosyl) derivatives 12 and 13, of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34c4e2e228c3bf8f54d030cb870271c
https://pubmed.ncbi.nlm.nih.gov/2167981
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10
Synthesis and antiviral activity of some 3'-C-difluoromethyl and 3'-deoxy-3'-C-fluoromethyl nucleosides
Autor: M. J. Bamford, Richard T. Walker, Paul L. Coe
Publikováno v: Journal of medicinal chemistry. 33(9)
The synthesis and antiviral activity of a number of 3'-C-difluoromethyl and 3'-deoxy-3'-C-fluoromethyl nucleosides are reported. The 3'-C-difluoromethyl nucleosides 26a and 26b were obtained by treatment of the corresponding 2',5'-di-O-protected-3'-C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884defd5b272cf297986570871ed9d37
https://pubmed.ncbi.nlm.nih.gov/2167980
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