Výsledky vyhledávání - "M J, van Esdonk"

The simplified oral flucloxacillin absorption test: an accurate method to identify patients with inadequate oral flucloxacillin absorption

Autor: A C, Dijkmans, D M, Kweekel, C, Balmforth, M J, van Esdonk, J T, van Dissel, J, Burggraaf, I M C, Kamerling

Publikováno v: The Netherlands journal of medicine. 77(7)

The preferred treatment for severe methicillin-sensitive Staphylococcus aureus infections is flucloxacillin, a small-spectrum antibiotic administered intravenously (IV) and orally. However, clinicians switch to the less preferred broad-spectrum antib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6235387cb7545c6610be7d7bb97c79cb
https://pubmed.ncbi.nlm.nih.gov/31582580

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Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability

Autor: Mirko Petrovic, Klaus T. Olkkola, Karel Allegaert, Dick Tibboel, Paola Mian, B.C.P. Koch, M. J. van Esdonk, Antti Liukas, Isabel Spriet, B. C. M. de Winter

Publikováno v: British Journal of Clinical Pharmacology, 85(1), 126-135. Wiley-Blackwell Publishing Ltd

AIMS: Paracetamol is the analgesic most used by older people. The physiological changes occurring with ageing influence the pharmacokinetics (PK) of paracetamol and its variability. We performed a population PK-analysis to describe the PK of intraven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ed749dfe208b871a43c89ad8aa61c7
https://pure.eur.nl/en/publications/ab611c04-4c6a-4161-a657-f822152642ba

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P67 Impact of enantiomer-specific maturational changes in pharmacokinetics on the racemic ketorolac target trough concentration

Autor: Dick Tibboel, Anne M. Lynn, Karel Allegaert, M. J. van Esdonk, Klaus T. Olkkola, M Cloesmeijer, Anne Smits, Youssef Daali, P Mian, Ehj Krekels

Publikováno v: Archives of Disease in Childhood. 104:e45.1-e45

IntroductionKetorolac is a racemic drug with analgesic effects specific to its S-enantiomer. This study aimed to describe enantiomer-specific maturational pharmacokinetics (PK). Simulations were performed to describe how S-ketorolac exposure in infan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f1b9a7df6e32b402e5c878ac7d18cc4
https://doi.org/10.1136/archdischild-2019-esdppp.105

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