Zobrazeno 1 - 10
of 3 390
pro vyhledávání: '"M J, Weaver"'
Autor:
Alvin Wei Tian Ng, Gianmarco Contino, Sarah Killcoyne, Ginny Devonshire, Ray Hsu, Sujath Abbas, Jing Su, Aisling M. Redmond, Jamie M. J. Weaver, Matthew D. Eldridge, Simon Tavaré, Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, Paul A. W. Edwards, Rebecca C. Fitzgerald
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Genomic structural variants (SVs) in cancer are notoriously difficult to identify, despite the impact they have on cancer progression and treatment efficacy. This study applies state-of-the-art computational methods to catalogue SVs in 383 cases of o
Externí odkaz:
https://doaj.org/article/0336bd3704d7461197a30b2d9ac48316
Autor:
Marc Abraham, Zoe Kordatou, Jorge Barriuso, Angela Lamarca, Jamie M J Weaver, Claudia Cipriano, George Papaxoinis, Alison Backen, Wasat Mansoor
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224540 (2019)
Cancer cachexia is common in patients with oesophagogastric cancer (OG) and is linked to overall survival (OS). One of the key components of cachexia is anorexia; it is not known whether anorexia impacts on OS and there is no method of routine screen
Externí odkaz:
https://doaj.org/article/3a70179684cf4679b883be202b35974f
Autor:
J M J Weaver, N. Masque Soler, Christopher C.W. Hughes, Rebecca C. Fitzgerald, K Lehovsky, Elizabeth C Smyth, Nicola Grehan, E. Ococks, Ginny Devonshire, H. Coles, Alexander M. Frankell, A. Northrop, A. Redmond, Adrienn Blasko, Barbara Nutzinger
Publikováno v:
Annals of Oncology. 32:522-532
The incidence of esophageal adenocarcinoma (EAC) is rapidly rising and has a 5-year survival rate of20%. Beyond TNM (tumor-node-metastasis) staging, no reliable risk stratification tools exist and no large-scale studies have profiled circulating tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841992542190424bcd7dd460c46e4e1f
https://doi.org/10.1016/j.annonc.2020.12.010
https://doi.org/10.1016/j.annonc.2020.12.010
Autor:
Alvin Wei Tian, Ng, Gianmarco, Contino, Sarah, Killcoyne, Ginny, Devonshire, Ray, Hsu, Sujath, Abbas, Jing, Su, Aisling M, Redmond, Jamie M J, Weaver, Matthew D, Eldridge, Simon, Tavaré, Paul A W, Edwards, Freddie, Bartlett
Publikováno v:
Communications biology. 5(1)
Oesophageal adenocarcinoma (OAC) provides an ideal case study to characterize large-scale rearrangements. Using whole genome short-read sequencing of 383 cases, for which 214 had matched whole transcriptomes, we observed structural variations (SV) wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d89d6d5a7baa34230806e45a908515c0
https://pubmed.ncbi.nlm.nih.gov/35396535
https://pubmed.ncbi.nlm.nih.gov/35396535
Autor:
Sofia Stamatopoulou, Magdy Nasralla, Vikki Owen-Holt, George Papaxoinis, Alan Anthoney, Theodora Germetaki, Zoe Kordatou, Wasat Mansoor, Jamie M J Weaver, Konstantinos Kamposioras
Publikováno v:
Journal of Gastrointestinal Surgery. 23:1729-1741
The aim of this cohort study was to assess the benefit that patients with lower esophageal or gastroesophageal junction (E/GEJ) adenocarcinoma receive by continuing perioperative chemotherapy post-surgery. Three hundred twelve patients underwent radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540b4c15371437dd40da9f3bf673ec4e
https://doi.org/10.1007/s11605-018-04087-8
https://doi.org/10.1007/s11605-018-04087-8
Autor:
Leila Khoja, Theodora Germetaki, Ana Patrao, Zoe Kordatou, Alia Alchawaf, George Papaxoinis, Sofia Stamatopoulou, Jamie M J Weaver, Vikki Owen-Holt, Wasat Mansoor
Publikováno v:
Acta Oncologica. 56:1224-1232
The new American Joint Committee on Cancer eighth edition (AJCC8) staging is the first to describe separate clinical and pathology staging systems, but still has low performance to predict prognosis in patients with oesophageal/gastroesophageal junct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e30de2076439fd867d95ae5adc4396a
https://doi.org/10.1080/0284186x.2017.1328127
https://doi.org/10.1080/0284186x.2017.1328127
Autor:
Jorge Barriuso, Claudia Cipriano, Zoe Kordatou, George Papaxoinis, Marc Abraham, Wasat Mansoor, Alison Backen, Angela Lamarca, Jamie M J Weaver
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224540 (2019)
PLoS ONE
PLoS ONE
Cancer cachexia is common in patients with oesophagogastric cancer (OG) and is linked to overall survival (OS). One of the key components of cachexia is anorexia; it is not known whether anorexia impacts on OS and there is no method of routine screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00ae5b4e6d4905d4c358248b184de0a
https://doaj.org/article/3a70179684cf4679b883be202b35974f
https://doaj.org/article/3a70179684cf4679b883be202b35974f
Autor:
Laura Woodhouse, Valentinos Kounnis, Konstantinos Kamposioras, Jamie M J Weaver, Brindley Sonal Hapuarachi, Neethu Billy Graham Mariam, Wasat Mansoor, Rebecca Lee, Richard A Hubner, Fiona Britton, Thomas K. Waddell, Adeel M Khan, Kathleen Connors, Jessica Coyle
Publikováno v:
Journal of Clinical Oncology. 39:4039-4039
4039 Background: Despite potentially curative surgery, long-term survival from OGC remains poor due to high relapse rate. Neoadjuvant (naFLOT) and adjuvant (aFLOT) FLOT is currently standard treatment for resectable OGC based on data from the FLOT-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::539c7d0ef6f47d6ac2bd9884eb5a438b
https://doi.org/10.1200/jco.2021.39.15_suppl.4039
https://doi.org/10.1200/jco.2021.39.15_suppl.4039
Publikováno v:
Annals of Oncology. 31:S496
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0a75de6fe4cf7e79a573f15a63bb191
https://doi.org/10.1016/j.annonc.2020.08.703
https://doi.org/10.1016/j.annonc.2020.08.703