Zobrazeno 1 - 9
of 9
pro vyhledávání: '"M J, Thirman"'
Autor:
S, Tanabe, N J, Zeleznik-Le, H, Kobayashi, C, Vignon, R, Espinosa, M M, LeBeau, M J, Thirman, J D, Rowley
Publikováno v:
Genes, chromosomescancer. 15(4)
The t(6;11)(q27;23) is one of the most common translocations observed in patients with acute myeloid leukemia (AML). The translocation breakpoint involves the MLL gene, which is the human homolog of the Drosophila trithorax gene, at 11q23 and the AF6
Autor:
P L, Broeker, H G, Super, M J, Thirman, H, Pomykala, Y, Yonebayashi, S, Tanabe, N, Zeleznik-Le, J D, Rowley
Publikováno v:
Blood. 87(5)
A major unresolved question for 11q23 translocations involving MLL is the chromosomal mechanism(s) leading to these translocations. We have mapped breakpoints within the 8.3-kb BamHI breakpoint cluster region in 31 patients with acute lymphoblastic l
Publikováno v:
Genes, chromosomescancer. 13(3)
The U937 cell line was studied with the fluorescence in situ hybridization (FISH) technique using phage and cosmid probes which were mapped and ordered on 11q. Although this cell line was thought to have a del(11q), FISH demonstrated that 11q was tra
Autor:
W, Stock, M J, Thirman, R K, Dodge, J D, Rowley, M O, Diaz, D, Wurster-Hill, R E, Sobol, F R, Davey, R A, Larson, C A, Westbrook
Publikováno v:
Leukemia. 8(11)
Specific structural rearrangements involving chromosome band 11q23 occur in a variety of hematologic malignancies, including an estimated 2-7% of patients with acute lymphoblastic leukemia (ALL). Translocations involving chromosome band 11q23 have be
Publikováno v:
Blood. 84(4)
Previously we had characterized the t(1;7)(p34;q34) translocation from HSB-2. This translocation fused the beta T-cell receptor gene (TCRB) constant region and transcriptional enhancer with the type I transcription unit of the LCK gene on the derivat
Autor:
H J, Super, N R, McCabe, M J, Thirman, R A, Larson, M M, Le Beau, J, Pedersen-Bjergaard, P, Philip, M O, Diaz, J D, Rowley
Publikováno v:
Blood. 82(12)
Chromosome band 11q23 is frequently involved in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) de novo, as well as in myelodysplastic syndromes (MDS) and lymphoma. Five percent to 15% of patients treated with chemotherapy for a p
Autor:
H, Kobayashi, R, Espinosa, M J, Thirman, H J, Gill, A A, Fernald, M O, Diaz, M M, Le Beau, J D, Rowley
Publikováno v:
Blood. 82(2)
Twenty-four patients whose cells contained a variety of 11q23 rearrangements, including translocations, insertions, and an inversion, were studied using fluorescence in situ hybridization with cosmid, phage, and plasmid probes mapped to 11q22-24. In
Publikováno v:
Blood. 81(11)
We mapped and ordered 17 cosmid, phage, and plasmid clones to chromosome 11, bands q22-q24, using fluorescence in situ hybridization (FISH). We then analyzed four hematopoietic cell lines with 11q23 rearrangements, Karpas 45, SUP-T13, RC-K8, and Karp
Publikováno v:
Bone marrow transplantation. 10(3)
We report a patient who underwent two allogeneic bone marrow transplants for chronic myelogenous leukemia, initially in 1984 and again after relapse in 1990, who developed an identical pulmonary syndrome at a similar interval following each transplan