Výsledky vyhledávání - "M J, Spinella"

Comparison of methotrexate polyglutamylation in L1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor. Lack of evidence for influx route-specific effects

Autor: M J, Spinella, K E, Brigle, S J, Freemantle, E E, Sierra, I D, Goldman

Publikováno v: Biochemical pharmacology. 52(5)

We previously described a methotrexate-resistant L1210 cell line (MTXrA) that lacks a functional reduced folate carrier and does not appreciably express the folate receptor. In the present study, we utilized MTXrA cell lines stably transfected with c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::15fcba37cde4bce9d81400e8ecdef6f0
https://pubmed.ncbi.nlm.nih.gov/8765468

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A proposed structural model of endothelin

Autor: M J, Spinella, S R, Krystek, D H, Peapus, B A, Wallace, C, Bruner, T T, Andersen

Publikováno v: Peptide research. 2(4)

We have assessed the hydropathic nature, secondary structure, and flexibility of endothelin and report a testable model for the structure of this 21-amino acid vasoconstrictor peptide. The proposed model consists of a rigid (disulfide bonded), hydrop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::faf060eae1bc289f6266566633cb7d84
https://pubmed.ncbi.nlm.nih.gov/2520767

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