Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M J, Sofia"'
Autor:
M. J. Sofia
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e95295bdabd79123c2a072f27d3f48b
https://doi.org/10.1002/chin.199709250
https://doi.org/10.1002/chin.199709250
Autor:
M J, Sofia, D J, Silva
Publikováno v:
Current opinion in drug discoverydevelopment. 2(4)
Carbohydrates and glycoconjugates have attracted a great deal of attention in recent years because of the key roles they play in biological processes. The development of carbohydrate-based libraries is a crucial step towards investigating the details
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef789c2382e64addb9b091799f4bde56
https://pubmed.ncbi.nlm.nih.gov/19649965
https://pubmed.ncbi.nlm.nih.gov/19649965
Autor:
W T, Jackson, L L, Froelich, R J, Boyd, J P, Schrementi, D L, Saussy, R M, Schultz, J S, Sawyer, M J, Sofia, D K, Herron, T, Goodson, D W, Snyder, P A, Pechous, S M, Spaethe, C R, Roman, J H, Fleisch
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(1)
The in vitro actions were investigated of LY293111, a potent and selective leukotriene B4 (LTB4) receptor antagonist, on human neutrophils, human blood fractions, guinea pig lung membranes, and guinea pig parenchymal and tracheal strips. The IC50 for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::996b6f278ef8a0043be276e322cdd84a
https://pubmed.ncbi.nlm.nih.gov/9862783
https://pubmed.ncbi.nlm.nih.gov/9862783
Autor:
M J, Sofia
Publikováno v:
Molecular diversity. 3(2)
Carbohydrate-based combinatorial libraries are tremendously valuable for studying the role of sugars in biology and for expanding accessible molecular diversity needed in broad-based drug screening programs. This review discusses the issues that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc2c4efb94a0cd926e4c974fd2a7733c
https://pubmed.ncbi.nlm.nih.gov/9593178
https://pubmed.ncbi.nlm.nih.gov/9593178
Autor:
M J, Sofia, P, Floreancig, N, Bach, S R, Baker, K, Nelson, J S, Sawyer, R, Baldwin, S L, Cockerham, J H, Fleisch, L L, Froelich, W T, Jackson, P, Marder, C R, Roman, D L, Saussy, S A, Silbaugh, S M, Spaethe, P W, Stengel
Publikováno v:
Advances in experimental medicine and biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54fe637429ecdefdf648b1dcf9b4cec6
https://pubmed.ncbi.nlm.nih.gov/9547580
https://pubmed.ncbi.nlm.nih.gov/9547580
Publikováno v:
Synfacts. 2011:0810-0810
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e861d0ce339c397253b07c7a8b5a499d
https://doi.org/10.1055/s-0030-1260674
https://doi.org/10.1055/s-0030-1260674
Autor:
J. Du, W. Stec, B.-K. Chun, J. Shi, M. J. Sofia, D. Cleary, B. S. Ross, S. Rachakonda, P. Wang, N. Khan
Publikováno v:
Synfacts. 2010:0141-0141
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83d68c4df628a1689f100d0f26da038e
https://doi.org/10.1055/s-0029-1219035
https://doi.org/10.1055/s-0029-1219035
Autor:
D S, Karanewsky, M C, Badia, C P, Ciosek, J A, Robl, M J, Sofia, L M, Simpkins, B, DeLange, T W, Harrity, S A, Biller, E M, Gordon
Publikováno v:
Journal of medicinal chemistry. 33(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33aac1ab9cdfb1274728f75e9c37ebfd
https://pubmed.ncbi.nlm.nih.gov/2231594
https://pubmed.ncbi.nlm.nih.gov/2231594
Autor:
M J, Sofia, J A, Katzenellenbogen
Publikováno v:
Journal of medicinal chemistry. 29(2)
We have found that alpha-aryl-substituted halo enol lactones (I and II) are effective mechanism-based inactivators for chymotrypsin. In this study, we have investigated, for comparative purposes, halo enol lactones with aryl functions situated beta a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::458bcf475054759f4861e038aae8e40d
https://pubmed.ncbi.nlm.nih.gov/3512826
https://pubmed.ncbi.nlm.nih.gov/3512826
Publikováno v:
The Journal of biological chemistry. 258(24)
Haloenol lactones can act as enzyme-activated irreversible inhibitors for alpha-chymotrypsin: acyl transfer to the active site serine releases a halomethyl ketone that remains tethered in the active site during the lifetime of the acyl enzyme, poised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6f79d18b5b678f9b430b31e3e85f516
https://pubmed.ncbi.nlm.nih.gov/6654902
https://pubmed.ncbi.nlm.nih.gov/6654902