Výsledky vyhledávání

Analysis of mechanisms underlying BRMS1 suppression of metastasis

Autor: R S, Samant, M J, Seraj, M M, Saunders, T S, Sakamaki, L A, Shevde, J F, Harms, T O, Leonard, S F, Goldberg, L, Budgeon, W J, Meehan, C R, Winter, N D, Christensen, M F, Verderame, H J, Donahue, D R, Welch

Publikováno v: Clinicalexperimental metastasis. 18(8)

Introduction of normal, neomycin-tagged human chromosome 11 (neo11) reduces the metastatic capacity of MDA-MB-435 human breast carcinoma cells by 70-90% without affecting tumorigenicity. Differential display comparing MDA-MB-435 and neo11/435 led to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d065bdd90870bf285af0d5e6f8a604a
https://pubmed.ncbi.nlm.nih.gov/11827072

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The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines

Autor: M J, Seraj, M A, Harding, J J, Gildea, D R, Welch, D, Theodorescu

Publikováno v: Clinicalexperimental metastasis. 18(6)

We have recently characterized a human bladder cancer cell line T24 and a more aggressive lineage related variant of it, T24T. To gain further insights, we have studied their metastatic ability in an in vivo model system. Results show that T24 forms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::860d3c0cbc44cd96f91e5068b7038282
https://pubmed.ncbi.nlm.nih.gov/11592309

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Molecular determination of perivesical and lymph node metastasis after radical cystectomy for urothelial carcinoma of the bladder

Autor: M J, Seraj, A R, Thomas, J L, Chin, D, Theodorescu

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 7(6)

Current methods used to determine the pathological stage of the primary tumor and associated lymphatics after radical cystectomy are tedious, costly, and may lack the sensitivity afforded by molecular approaches such as reverse transcription-PCR (RT-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1f62ae6707af443c4d5c42a8f10d4548
https://pubmed.ncbi.nlm.nih.gov/11410485

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Breast cancer metastatic potential correlates with a breakdown in homospecific and heterospecific gap junctional intercellular communication

Autor: M M, Saunders, M J, Seraj, Z, Li, Z, Zhou, C R, Winter, D R, Welch, H J, Donahue

Publikováno v: Cancer research. 61(5)

Breast cancer progresses toward increasingly malignant behavior in tumorigenic and metastatic stages. In the series of events in the metastatic stage, tumor cells leave the primary tumor in breast and travel to distant sites where they establish seco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df5beb488c86093930f43999bce8c2e0
https://pubmed.ncbi.nlm.nih.gov/11280719

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Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13

Autor: M J, Seraj, R S, Samant, M F, Verderame, D R, Welch

Publikováno v: Cancer research. 60(11)

We previously showed that introduction of a normal, neomycin-tagged human chromosome 11 reduces the metastatic capacity of MDA-MB-435 (435) human breast carcinoma cells by 70-90% without affecting tumorigenicity, suggesting the presence of one or mor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::92f72cb79d1aa1d2f2ad2f2173de3da0
https://pubmed.ncbi.nlm.nih.gov/10850410

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