Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M J, Seckl"'
Autor:
R. C. Coombes, P. D. Badman, J. P. Lozano-Kuehne, X. Liu, I. R. Macpherson, I. Zubairi, R. D. Baird, N. Rosenfeld, J. Garcia-Corbacho, N. Cresti, R. Plummer, A. Armstrong, R. Allerton, D. Landers, H. Nicholas, L. McLellan, A. Lim, F. Mouliere, O. E. Pardo, M. J. Seckl
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
FGFR-1 upregulation has been associated with endocrine therapy resistance in breast cancer patients. Here the authors report the results of a phase IIa study to assess the safety and efficacy of AZD454, an inhibitor of FGFR-1, 2 and 3 receptor tyrosi
Externí odkaz:
https://doaj.org/article/dd21946084ab4cad9d70fb08c6b96016
Autor:
R. C. Coombes, P. D. Badman, J. P. Lozano-Kuehne, X. Liu, I. R. Macpherson, I. Zubairi, R. D. Baird, N. Rosenfeld, J. Garcia-Corbacho, N. Cresti, R. Plummer, A. Armstrong, R. Allerton, D. Landers, H. Nicholas, L. McLellan, A. Lim, F. Mouliere, O. E. Pardo, V. Ferguson, M. J. Seckl
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a49b3f62276b4ad18eb4fc87fff91c8d
Autor:
C R, Schlegel, M L, Georgiou, M B, Misterek, S, Stöcker, E R, Chater, C E, Munro, O E, Pardo, M J, Seckl, A P, Costa-Pereira
Publikováno v:
Cell Death & Disease
Death-associated protein kinase (DAPK) 2 is a serine/threonine kinase that belongs to the DAPK family. Although it shows significant structural differences from DAPK1, the founding member of this protein family, DAPK2 is also thought to be a putative
Autor:
T, Powles, A, Young, A, Sanitt, A, Sammit, J, Stebbing, D, Short, M, Bower, P M, Savage, M J, Seckl, P, Schmid
Publikováno v:
British Journal of Cancer
Europe PubMed Central
Europe PubMed Central
It is thought that the time interval between the antecedent pregnancy and diagnosis of gestational trophoblastic tumours (GTTs) may influence the outcome of these patients. In this study, we investigate the significance of this time interval. Multiva
Publikováno v:
British Journal of Surgery. 84:1022-1025
Background Primary retroperitoneal germ cell tumours usually present as a large abdominal mass in young men. The testes are normal on examination and ultrasonography but there are usually raised serum levels of human chorionic gonadotrophin and/or a-
Autor:
S, Saso, J, Chatterjee, J, Yazbek, Y, Thum, K W, Keefe, Y, Abdallah, O, Naji, I, Lindsay, P M, Savage, M J, Seckl, J R, Smith
Publikováno v:
BJOG : an international journal of obstetrics and gynaecology. 119(13)
Publikováno v:
BJOG : an international journal of obstetrics and gynaecology. 119(3)
The standard management of placental site trophoblastic tumours (PSTTs) is a radical hysterectomy with pelvic lymph node sampling. We present five cases to demonstrate a modified Strassman procedure (MSP), which is an alternative fertility-sparing te
Publikováno v:
BJOG : an international journal of obstetrics and gynaecology. 118(13)
Autor:
Jun, Zhao, Yang, Xiang, Shang-zhi, Huang, Xi-run, Wan, Quan-cai, Cui, M J, Seckl, R A, Fisher
Publikováno v:
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. 23(5)
To determine the parental origin of the genome in the molar pregnancies of two familes with familial recurrent hydatidiform mole (FRHM) and to investigate whether the gene responsible for FRHM is likely to be located within the 19q13.4 region in thes
Publikováno v:
BJOG : an international journal of obstetrics and gynaecology. 110(1)
To determine pregnancy outcome, including the rate of repeat molar pregnancy, following histologically confirmed complete or partial hydatidiform mole.Retrospective review of a large supraregional database of registrations for gestational trophoblast