Zobrazeno 1 - 10
of 20
pro vyhledávání: '"M J, Rohrer"'
Autor:
S. Francis, Gina Ragno, Gilbert R. Upchurch, M. J. Rohrer, C. R. Valeri, H. MacGregor, George N. Welch, Shukri F. Khuri, Alan D. Michelson, L. J. Rodino, Joseph Loscalzo
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 271:H528-H534
Heparin, a polyanionic glycosaminoglycan, is used routinely before the induction of cardiopulmonary bypass. Earlier observations in our laboratory suggested that the postoperative bleeding that occurs, despite neutralization of heparin with protamine
Publikováno v:
Blood. 83:3562-3573
Thrombin decreases the platelet surface expression of the glycoprotein (GP) Ib-IX complex. To determine whether this effect is reversible, flow cytometric studies were performed with GPIb-IX-specific monoclonal antibodies. In both whole blood and was
Publikováno v:
Thrombosis and Haemostasis. 71:633-640
SummaryA hypothermia-induced hemorrhagic diathesis is associated with cardiopulmonary bypass, major surgery, and multiple trauma, but its pathophysiological basis is not well understood. We examined the hypothesis that hypothermia reversibly inhibits
Publikováno v:
Cardiovascular Surgery. 1:362-368
The effect of endothelial cell seeding on the patency of small-caliber expanded polytetrafluoroethylene (ePTFE) grafts used for venous replacements in a canine experimental model was evaluated. Grafts were implanted bilaterally In 12 dogs as femoral
Autor:
R B, Claytor, J M, Li, M I, Furman, C S, Garnette, M J, Rohrer, M R, Barnard, L A, Krueger, A L, Frelinger, A D, Michelson
Publikováno v:
Cytometry. 43(4)
Adherence of platelets to endothelial cells may be a significant event in the development of vascular thrombosis. Existing models, which examine platelet-endothelial cell interactions, compromise endothelial cell integrity or use radioactivity to ide
Publikováno v:
Cancer. 89(12)
Angiotropic large cell lymphoma (ALCL) is characterized by the intravascular proliferation of malignant lymphoid cells in small and medium-sized blood vessels. In the current study, the authors report an unusual case in which the initial presentation
Publikováno v:
British journal of haematology. 104(1)
Patients undergoing hypothermic cardiopulmonary bypass are often receiving aspirin therapy. Hypothermia, aspirin and cardiopulmonary bypass can each induce a platelet function defect, but it is not known if the effects of aspirin and hypothermia are
Publikováno v:
The Journal of cardiovascular surgery. 37(5)
Heparin has been shown to decrease total vascular resistance while protamine stimulates endothelium-dependent vasodilation. This study was undertaken to determine whether heparin and/or protamine could enhance endothelium-derived relaxing factor (EDR
Autor:
M J, Rohrer, F A, Anderson
Publikováno v:
Seminars in vascular surgery. 9(1)
Publikováno v:
The Journal of surgical research. 61(2)
Normal circulating platelets do not adhere to intact, undisturbed endothelium. Studies have shown, however, that platelets will adhere to virally infected or thrombin-stimulated human umbilical vein endothelial cells. Using a novel platelet/endotheli