Zobrazeno 1 - 10
of 28
pro vyhledávání: '"M J, Rapoport"'
Publikováno v:
Current Rheumatology Reviews. 7:301-305
Loss of self tolerance is the key feature of autoimmunity. The p21Ras/MAP kinase pathway plays a major role in the regulation, selection, differentiation and maturation of lymphocytes. Therefore it is conceivable that malfunctioning of this pathway d
Autor:
M. Weiss, T. Lazarovitch, M. J. Rapoport, I. Boldur, A. Buchs, A. Hindi, Robert A. Slater, Y. Ramot
Publikováno v:
Diabetic Medicine. 21:705-709
Aims Current clinical practice assumes swab cultures from wounds are unreliable. However, this assumption is based upon data culled only from wounds in which osteomyelitis and/or gangrene were present. This study aimed to re-evaluate the accuracy of
Publikováno v:
Experimental Diabesity Research
The aim of the study was to determine the correlation between the expression of tissue factor (TF) and the receptor for advanced glycation end products (RAGEs) and vascular complications in patients with longstanding uncontrolled type 2 diabetes (T2D
Autor:
A Halevi, Y. Ramot, D. Aharoni, Ohad Cohen, O Bloch, E Scapa, Mordechai Weiss, M. J. Rapoport, N Bendet
Publikováno v:
Scandinavian Journal of Gastroenterology. 39:650-656
Enhanced secretion of glucagon-like peptide-1 (GLP-1) has been reported in patients with Crohn disease (CD). However, the correlation between the enteropancreatic axis and the activity of CD remains unclear.Plasma glucose, insulin, GLP-1 levels and i
Autor:
T. Bistritzer, Andreas Buchs, A. Kornberg, D. Aharoni, M. J. Rapoport, E. Broide, A. Mizrachi
Publikováno v:
Scandinavian Journal of Gastroenterology. 37:924-930
Celiac disease (CD) is commonly believed to be a predominantly Th1 disease. However, the exact balance between the Th1 and Th2 arms, as well as the correlation to clinical parameters, remains unclear. The aim was to assess the Th1/Th2 cytokine profil
Publikováno v:
The Journal of Immunology. 157:4721-4725
Oral therapy with linomide protects prediabetic nonobese diabetic (NOD) mice from insulin-dependent diabetes mellitus. The mechanisms by which linomide exerts its protective effect are not fully understood. A decreased TCR-mediated activity of the GT
Publikováno v:
The Journal of Experimental Medicine
Ligation of a B lymphocyte surface immunoglobulin (sIg) antigen receptor (AgR) by its specific Ag ligand initiates a signaling pathway that culminates in B cell activation. However, many events of this pathway have not been elucidated. Here we presen
Autor:
David V. Serreze, Jayne S. Danska, Andrés Jaramillo, E H Leiter, Terry L. Delovitch, D Zipris, Alan H. Lazarus, P Cyopick, M J Rapoport
Publikováno v:
The Journal of Experimental Medicine
Beginning at the time of insulitis (7 wk of age), CD4+ and CD8+ mature thymocytes from nonobese diabetic (NOD) mice exhibit a proliferative unresponsiveness in vitro after T cell receptor (TCR) crosslinking. This unresponsiveness does not result from
Autor:
A. Krook, Tina Haliotis, S K Anderson, Yu Chun Zhou, T. L. Delovitch, D. T. Denhardt, M. J. Rapoport, Hugh F. Pross
Publikováno v:
Molecular and Cellular Biology. 13:1471-1479
Both p21ras and protein kinase C (PKC) are believed to function downstream of plasma membrane-associated tyrosine kinases in cellular signal transduction pathways. However, it has remained controversial whether they function in the same pathway and,
Publikováno v:
International journal of clinical practice. 64(13)
It is undecided whether glucose control as advocated by the professional organisations and the glucose-lowering method by itself affects clinical outcome in patients with diabetes mellitus hospitalised in general medical wards. Our aim was to investi