Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M J, Radeke"'
Autor:
M. J. Radeke, A. M. Giannetti, M. F. Chau, G. Lindwall, Stuart C. Feinstein, L. A. Kohlstaedt
Publikováno v:
Protein Science. 9:2427-2435
We have used X-ray fiber diffraction to probe the structure of fibers of tau and tau fragments. Fibers of fragments from the microtubule binding domain had a cross beta-structure that closely resembles that reported both for neurofibrillary tangles f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12350b47516e189aff0c84f0628630b4
https://doi.org/10.1110/ps.9.12.2427
https://doi.org/10.1110/ps.9.12.2427
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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The interaction between tubulin subunits and microtubule-associated proteins (MAPs) such as tau is fundamental for microtubule structure and function. Previous work has suggested that the 'microtubule biding domain' of tau (composed of three or four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4078ffb9c6564b438331a18b852ee01
https://doi.org/10.1021/bi9812118
https://doi.org/10.1021/bi9812118
Autor:
T. P. Misko, Georg Dechant, Dan Lindholm, M. J. Radeke, Eric M. Shooter, Hans Thoenen, Ronald M. Lindsay
Publikováno v:
European Journal of Neuroscience. 2:389-396
Sensory neurons of the adult rat dorsal root ganglion (DRG) can be maintained in culture in the absence of nerve growth factor (NGF). We have thus used dissociated cultures of these neurons to study effects of NGF on the regulation of expression of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6891760a821735fb76dcfc8435c2c07
https://doi.org/10.1111/j.1460-9568.1990.tb00431.x
https://doi.org/10.1111/j.1460-9568.1990.tb00431.x
Publikováno v:
Investigative ophthalmologyvisual science. 41(2)
To determine the mechanism by which basic fibroblast growth factor (bFGF) exerts its neuroprotective effects on degenerating or injured photoreceptors.Confocal immunofluorescence microscopy was used to identify sites of bFGF and FGF receptor 1 (FGFR1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e50693af17ed59d54b0cae04571b103b
https://pubmed.ncbi.nlm.nih.gov/10670490
https://pubmed.ncbi.nlm.nih.gov/10670490
Autor:
R R, Sukhov, M H, Cayouette, M J, Radeke, S C, Feinstein, D, Blumberg, A, Rosenthal, D L, Price, V E, Koliatsos
Publikováno v:
The Journal of comparative neurology. 383(2)
Nerve growth factor (NGF), which has long been considered to be a trophic factor for peripheral sensory and sympathetic neurons, has been found recently to influence cholinergic neurons in the basal forebrain and neostriatum. In the present study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3efab0e003be27dfdccb557fda523d23
https://pubmed.ncbi.nlm.nih.gov/9182843
https://pubmed.ncbi.nlm.nih.gov/9182843
Publikováno v:
The Journal of comparative neurology. 378(1)
The TrkB family of transmembrane proteins serve as receptors for brain-derived neurotrophic factor (BDNF), neurotrophin (NT)-4/5, and possibly NT-3, three members of the neurotrophin family of neurotrophic factors. In order to understand the potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c8983e3c01c06e0d97ee04aacb11c2d
https://pubmed.ncbi.nlm.nih.gov/9120052
https://pubmed.ncbi.nlm.nih.gov/9120052
Developmental and mature expression of full-length and truncated TrkB receptors in the rat forebrain
Publikováno v:
The Journal of comparative neurology. 374(1)
The neurotrophins brain-derived neurotrophic factor (BDNF) and NT-4/5 exert their trophic effects on the nervous system via signaling through trkB receptors. These receptors occur as splice variants of the trkB gene that encodes a full-length recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5160b447be74a5f186953cab55348696
https://pubmed.ncbi.nlm.nih.gov/8891944
https://pubmed.ncbi.nlm.nih.gov/8891944
Autor:
K, Washiyama, Y, Muragaki, L B, Rorke, V M, Lee, S C, Feinstein, M J, Radeke, D, Blumberg, D R, Kaplan, J Q, Trojanowski
Publikováno v:
The American journal of pathology. 148(3)
Primitive neuroectodermal tumors (PNETs) of the central nervous system (CNS) are poorly understood childhood neoplasms, and medulloblastomas are the most common pediatric PNETs. Neoplastic cells in medulloblastomas and other PNETs resemble progenitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47a9e664523ef22bd53a299211c5ef9d
https://pubmed.ncbi.nlm.nih.gov/8774147
https://pubmed.ncbi.nlm.nih.gov/8774147
Publikováno v:
Journal of Experimental Biology. 132:177-190
One of the major roles of nerve growth factor (NGF) is to mediate the selective survival of a proportion of the developing sympathetic and sensory neurones as they innervate their particular target tissues. The underlying basis of this phenomenon is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d1d473d3a9b65e4935884bbe5730da
https://doi.org/10.1242/jeb.132.1.177
https://doi.org/10.1242/jeb.132.1.177
Publikováno v:
Journal of Biological Chemistry. 261:313-318
A rapid light-induced decrease in cGMP is thought to play a role in regulating the permeability or light sensitivity of photoreceptor membranes. Photo-excited rhodopsin activates a guanine nucleotide-binding protein (G-protein) by catalyzing the exch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30a625b3257e87bc13c06efe3d947d4d
https://doi.org/10.1016/s0021-9258(17)42471-9
https://doi.org/10.1016/s0021-9258(17)42471-9