Zobrazeno 1 - 10
of 95
pro vyhledávání: '"M J, Picker"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(2)
Effects of low (butorphanol, nalbuphine)-, intermediate (buprenorphine)-, and high (morphine, levorphanol)-efficacy mu opioids were examined in F344, Sprague-Dawley (SD), Long-Evans (LE), and Lewis rats using a tail withdrawal and a drug discriminati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca504760651dde5c0ac954ed84b4fbed
https://pubmed.ncbi.nlm.nih.gov/10215676
https://pubmed.ncbi.nlm.nih.gov/10215676
Autor:
M J, Picker
Publikováno v:
Experimental and clinical psychopharmacology. 6(2)
In pigeons (Columba livia; N = 5) trained to discriminate the mu (mu) opioid butorphanol from saline, various mu (morphine, fentanyl) but not kappa (kappa; bremazocine, U50,488, U69,593) opioids produced at least 80% drug-appropriate responding. Subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0f801020462ba1395ee346619df2eb9
https://pubmed.ncbi.nlm.nih.gov/9608345
https://pubmed.ncbi.nlm.nih.gov/9608345
Autor:
M J, Picker
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(3)
The purpose of this investigation was to evaluate the discriminative stimulus effects of the mixed-opioid agonist/antagonist dezocine. In pigeons trained to discriminate 1.7 mg/kg dezocine from saline, a series of opioids with activity at the mu opio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a1bb2aa5d941ac43752015d1542733f
https://pubmed.ncbi.nlm.nih.gov/9399970
https://pubmed.ncbi.nlm.nih.gov/9399970
Autor:
M J, Picker, C D, Cook
Publikováno v:
Behavioural pharmacology. 8(2-3)
The purpose of the present investigation was to examine the discriminative stimulus effects of opioids with activity at mu and kappa opioid receptors, in pigeons trained to discriminate the mu opioid fentanyl, the kappa opioid bremazocine and water i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8895cd806af2284b93d9805cd54a84eb
https://pubmed.ncbi.nlm.nih.gov/9833011
https://pubmed.ncbi.nlm.nih.gov/9833011
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 279(3)
The discriminative stimulus effects of butorphanol were examined in separate groups of pigeons trained to discriminate either a low (0.1 mg/kg), medium (1.0 mg/kg) or high (5.6 mg/kg) dose of butorphanol from saline. The mu-selective opioid antagonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d50171dfd616431e0aab7843c815e1af
https://pubmed.ncbi.nlm.nih.gov/8968334
https://pubmed.ncbi.nlm.nih.gov/8968334
Autor:
M J, Picker
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 268(3)
Previous investigations indicate that mixed action opioids (i.e., opioids with activity at a combination of opioid receptor sites or a combination of opioid and nonopioid sites) often possess kappa-like stimulus effects in the rat and monkey, but mu-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fc7ba136785f66175f84fdad670ffee
https://pubmed.ncbi.nlm.nih.gov/8138931
https://pubmed.ncbi.nlm.nih.gov/8138931
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 266(2)
The stimulus effects of selective, high efficacy mu opioids and mixed action opioids with varying degrees of intrinsic efficacy at the mu receptor were examined in pigeons trained to discriminate between saline and either 0.056 (low) or 0.18 (high) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::901b1e108ba4a3701b01e0766279e558
https://pubmed.ncbi.nlm.nih.gov/8394915
https://pubmed.ncbi.nlm.nih.gov/8394915
Autor:
M J, Picker, R M, Craft, S S, Negus, K R, Powell, S R, Mattox, S R, Jones, B K, Hargrove, L A, Dykstra
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(2)
The present study examined the effects of morphine, the intermediate efficacy mu opioids (-)-pentazocine, (-)-metazocine, proxorphan, levallorphan, (-)-NANMY (N-allylnormetazocine) and (-)-cyclazocine, and the mu antagonist naloxone 1) in rats respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99ef6e6a569da2586ffbaed90fda6165
https://pubmed.ncbi.nlm.nih.gov/1331411
https://pubmed.ncbi.nlm.nih.gov/1331411
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 256(1)
A series of mu and kappa opioid agonists with varying degrees of selectivity were evaluated for their agonist and antagonist effects in squirrel monkeys trained to discriminate either the selective mu agonist fentanyl or the selective kappa agonist U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::093490a1a440a3064854a13d896bdba3
https://pubmed.ncbi.nlm.nih.gov/1846412
https://pubmed.ncbi.nlm.nih.gov/1846412
Publikováno v:
NIDA research monograph. 105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfbb240b360b3fd2fa61de2d795cd928
https://pubmed.ncbi.nlm.nih.gov/1876046
https://pubmed.ncbi.nlm.nih.gov/1876046