Genetic risk for schizophrenia is associated with increased proportion of indirect connections in brain networks revealed by a semi-metric analysis: Evidence from population sample stratified for polygenic risk

Autor: S I Dimitriadis, G Perry, T M Lancaster, K E Tansey, K D Singh, P Holmans, A Pocklington, G Davey Smith, S Zammit, J Hall, M C O’Donovan, M J Owen, D K Jones, D E Linden

Publikováno v: Cerebral Cortex, 33:bhac256, 2997-3011. Oxford University Press
Dimitriadis, S L, Perry, G, Lancaster, T, Tansey, K, Singh, K D, Holmans, P, Pocklington, A, Davey Smith, G, Zammit, S, Hall, J, O'Donovan, M C, Owen, MJ, Jones, D K & Linden, DE 2022, ' Genetic risk for schizophrenia is associated with increased proportion of indirect connections in brain networks revealed by a semi-metric analysis : Evidence from population sample stratified for polygenic risk ', Cerebral Cortex . https://doi.org/10.1093/cercor/bhac256

Research studies based on tractography have revealed a prominent reduction of asymmetry in some key white-matter tracts in schizophrenia (SCZ). However, we know little about the influence of common genetic risk factors for SCZ on the efficiency of ro

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Sleep EEG in young people with 22q11.2 deletion syndrome: a cross-sectional study of slow-waves, spindles and correlations with memory and neurodevelopmental symptoms

Autor: Matt Jones, JE Hall, C Eaton, Jeremy Hall, Mbm van den Bree, NA Donnelly, Hugh Marston, H A Moulding, M. J. Owen, Ullrich Bartsch

BackgroundYoung people living with 22q11.2 Deletion Syndrome (22q11.2DS) are at increased risk of schizophrenia, intellectual disability, attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). In common with these conditi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7878efa3ace8caad2cf8f1d3a166e11
https://doi.org/10.1101/2021.11.08.21266020

Neurodevelopmental Disorders and Schizophrenia: Recent Developments

Autor: Jeremy Hall, Kimberley Kendall, M. J. Owen

Publikováno v: Oxford Textbook of the Psychiatry of Intellectual Disability

In this chapter the occurrence of schizophrenia, other psychotic disorders, psychotic symptoms in intellectual disability, and autism spectrum disorder is considered, as are the similarities in clinical features between these disorders. Also reviewed

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https://doi.org/10.1093/med/9780198794585.003.0021

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression

Autor: Ian J. Deary, Cathryn M. Lewis, Mark Adams, Steven P. Hamilton, Yuri Milaneschi, David M. Howard, Darina Czamara, Stanley I. Shyn, Jri Coleman, Giorgio Pistis, Tracy Air, Lisa Jones, Saskia P. Hagenaars, Elisabeth B. Binder, D. H. R. Blackwood, P.F. Sullivan, Naomi R. Wray, Tfm Andlauer, Bernhardt T. Baune, David J. Porteous, Udo Dannlowski, D.I. Boomsma, Karen Hodgson, V. Arolt, Susanne Lucae, Stephan Ripke, Martin Preisig, Micah Cearns, M. J. Owen, Campbell A, Bwjh Penninx, N. G. Martin, Zoltán Kutalik, Ian Jones, Ian B. Hickie, Helena Gaspar, Caroline Hayward, John Whitfield, Andrew M. McIntosh, Sandosh Padmanabhan, Matthew Traylor, Ejc de Geus, Shing Wan Choi, Bertram Mueller-Myhsok, Marcus Ising, Katharina Domschke, J-J Hottenga, Gerome Breen

IntroductionIt’s imperative to understand the specific and shared aetiologies of major depression and cardio-metabolic disease, as both traits are frequently comorbid and each represents a major burden to society. This study examined whether there

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Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Autor: Roseann E. Peterson, EM Byrne, M J Owen, Sven Cichon, Gcb Sinnamon, Jian Yang, Stephan Ripke, Andreas J. Forstner, Stephanie H. Witt, TM Air, Isaac S. Kohane, M. Rietschel, Tõnu Esko, Jakob Grove, Eske M. Derks, Hans-Jörgen Grabe, Christine Søholm Hansen, Hualin S. Xi, Kenneth I. Berger, A. C. Heath, Henry Völzke, Manuel Mattheisen, Bernard Ng, Hamdi Mbarek, Stefan Kloiber, Jodie N. Painter, Marianne Giørtz Pedersen, Jerome C. Foo, Carsten Horn, Yang Wu, Alexander Viktorin, Hilary K. Finucane, Paf Madden, Lili Milani, Katharina Domschke, Yun Li, Bernard T. Baune, I. Jones, M. M. Nöthen, Atf Beekman, Eric Jorgenson, Matthew Hotopf, Christopher Rayner, Giorgio Pistis, Stanley I. Shyn, J.H. Smit, A Abdellaoui, N. G. Martin, Paul F. O'Reilly, Enrico Domenici, Daphna Levinson, John P. Rice, Thomas Werge, Ling Shen, Catherine Schaefer, Andrea Danese, Jonathan Marchini, Na Cai, Michel G. Nivard, Scott D. Gordon, Shantel Weinsheimer, Steven P. Hamilton, G. Homuth, Yunpeng Wang, David M. Hougaard, Andres Metspalu, Nese Direk, Gonneke Willemsen, Francis M. Mondimore, J-J Hottenga, M. Gill, S. E. Medland, Donald M. Lyall, Peter Hoffmann, Merete Nordentoft, Udo Dannlowski, Stacy Steinberg, Tfm Andlauer, Ian J. Deary, Caroline Hayward, Cathryn M. Lewis, Penelope A. Lind, Nancy L. Pedersen, David J. Porteous, Hogni Oskarsson, D.I. Boomsma, Evelin Mihailov, Thorgeir E. Thorgeirsson, Evangelos Vassos, Rudolf Uher, Gary Davies, Gerome Breen, KW Choi, Christopher Hübel, Carol Kan, Sara A. Paciga, Kirstin L. Purves, Torben Hansen, Jri Coleman, Naomi R. Wray, Erin C. Dunn, Engilbert Sigurdsson, Bradley T. Webb, Jorge A. Quiroz, van, Hemert, Am, Christel M. Middeldorp, Jonas Bybjerg-Grauholm, Robert A. Schoevers, Maciej Trzaskowski, Jing Shi, Ole Mors, Alexander Teumer, Fernando S. Goes, S-A Bacanu, James B. Potash, David J. Smith, Niamh Mullins, EB Binder, J Bryois, Dean F. MacKinnon, Arolt, Daniel Umbricht, Andrew M. McIntosh, P. B. Mortensen, Anders D. Børglum, Futao Zhang, Susanne Lucae, W. Maier, Eva C. Schulte, Jens Treutlein, Carsten Bøcker Pedersen, Henning Tiemeier, Grant W. Montgomery, Trubetskoy, Thomas G. Schulze, Martin Preisig, Bwjh Penninx, TB Bigdeli, Thalia C. Eley, Shing Wan Choi, Robert Maier, E Agerbo, Katherine E. Tansey, P. McGuffin, James A. Knowles, de, Geus, Ejc, Franziska Degenhardt, Jane H. Christensen, Julia Kraft, Enrique Castelao, Ian B. Hickie, Helena Gaspar, Danielle Posthuma, K. Stefansson, Gregory E. Crawford, Wesley K. Thompson, Kas Davis, Jana Strohmaier, Henriette N. Buttenschøn, Margarita Rivera, Josef Frank, Van der Auwera S, Fabian Streit, Erik Pettersson, Peter M. Visscher, Donald J. MacIntyre, Qingqin S. Li, Rick Jansen, Conor V. Dolan, Matthias Nauck, Barbara Maughan, Escott-Price, Glyn Lewis, Patrick K.E. Magnusson, Henning Teismann, DePaulo, Saira Saeed Mirza, Sara Mostafavi, Kenneth S. Kendler, Matthew Traylor, Brien P. Riley, Roy H. Perlis, Patrick J. McGrath, Bertram Müller-Myhsok, Mark Adams, David M. Howard, Lucía Colodro-Conde, Lisa Hall, Divya Mehta, Nyholt, Y. Milaneschi, Jordan W. Smoller, M Baekvad-Hansen, Marcus Ising, M O'Donovan, Warren W. Kretzschmar, Baptiste Couvy-Duchesne, Wouter J. Peyrot, P. A. Thomson, P.F. Sullivan, Stefan Herms, Clarke T, Ffh Kiadeh, Jürgen Wellmann, Lisa Jones, A.G. Uitterlinden, Per Qvist, Z. Kutalik, Hreinn Stefansson, Myrna M. Weissman, N. Craddock

Publikováno v: on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2021, ' Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 26, no. 9, pp. 5465-5465 . https://doi.org/10.1038/s41380-020-0779-4

Following publication of this article, the authors noticed an error in Supplementary Table 1. In the original Supplementary Table 1, one of the criteria for control participants was incorrectly given as ‘Report extensive recent symptoms of depressi

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https://doi.org/10.1038/s41380-020-0779-4