Zobrazeno 1 - 2
of 2
pro vyhledávání: '"M J, Neeb"'
Autor:
D J, Behm, N V, Aiyar, A R, Olzinski, J J, McAtee, M A, Hilfiker, J W, Dodson, S E, Dowdell, G Z, Wang, K B, Goodman, C A, Sehon, M R, Harpel, R N, Willette, M J, Neeb, C A, Leach, S A, Douglas
Publikováno v:
British journal of pharmacology. 161(1)
Recently identified antagonists of the urotensin-II (U-II) receptor (UT) are of limited utility for investigating the (patho)physiological role of U-II due to poor potency and limited selectivity and/or intrinsic activity.The pharmacological properti
Autor:
D J, Behm, J J, McAtee, J W, Dodson, M J, Neeb, H E, Fries, C A, Evans, R R, Hernandez, K D, Hoffman, S M, Harrison, J M, Lai, C, Wu, N V, Aiyar, E H, Ohlstein, S A, Douglas
Publikováno v:
British journal of pharmacology. 155(3)
The recent development of the UT ligand palosuran (1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea sulphate salt) has led to the proposition that urotensin-II (U-II) plays a significant pathological role in acute and c