Zobrazeno 1 - 10
of 40
pro vyhledávání: '"M J, Mitchinson"'
Publikováno v:
British Journal of Urology. 43:444-449
Publikováno v:
Free Radical Research. 30:341-350
Different parts of the advanced atherosclerotic lesion have characteristic differences in lipid content, but the distribution of lipid oxidation products has not been reported. This study provides novel data on oxysterol and hydroxyoctadecadienoic ac
Autor:
Keri L.H. Carpenter, Francesc Guardiola, Bridget K. Stein, M. J. Mitchinson, Sandra Garcia-Cruset
Publikováno v:
Scopus-Elsevier
Human atherosclerotic lesions of different stages have quantitative differences in cholesterol and oxysterol content, but information on the oxysterol profile in fatty streaks is limited. This study aims to provide more detailed oxysterol quantificat
Autor:
J N, Skepper, I, Karydis, M R, Garnett, L, Hegyi, S J, Hardwick, A, Warley, M J, Mitchinson, N R, Cary
Publikováno v:
The Journal of pathology. 188(1)
This study examines ion homeostasis in monocyte-macrophages committed to death by apoptosis. X-ray microanalysis has been used to demonstrate that intracellular concentrations of potassium decreased whilst those of sodium increased following 3 h of e
Publikováno v:
The Journal of pathology. 180(4)
A characteristic feature of the advanced atherosclerotic lesion is the acellular lipid core, which appears to result at least partly from the death of macrophage foam cells. This study shows that foam cell death at the edge of the lipid core includes
Publikováno v:
The Journal of pathology. 179(3)
This study has demonstrated the toxicity to human monocyte-macrophages of low-density lipoprotein (LDL) which had been artificially oxidized using copper sulphate. The assays of cell damage used were tritiated adenine release, neutral red staining, l
Autor:
Katharine Clare, S. E. Taylor, Laszlo Hegyi, Simon J. Hardwick, C. van der Veen, M. J. Mitchinson, Keri L.H. Carpenter
Publikováno v:
Gerontology. 41
Necropsy samples of atherosclerotic lesions of different histological stages have been analysed. Ceroid was present in all the lesions, within lipid-laden macrophage foam cells and extracellularly in the atheromatous core of advanced lesions. Mean le
Publikováno v:
Archives of pathologylaboratory medicine. 114(4)
The incidence of serum antibodies to human low-density lipoprotein, to oxidized low-density lipoprotein, and to ceroid extracted from human atheroma was assessed in 100 subjects using an adaptation of the enzyme-linked immunosorbent assay technique.
Publikováno v:
The American journal of cardiovascular pathology. 3(2)
During repair of an inflammatory abdominal aortic aneurysm, fresh samples of the aneurysm wall were obtained. Histology confirmed the diagnosis of chronic periaortitis,- advanced atherosclerosis with medial attenuation, and periaortic inflammation. M
Autor:
Woods Se, Keri L.H. Carpenter, S. L. Hartley, Davies S, M. J. Mitchinson, J. H. Enright, R. Y. Ball, N. P. Carter
Publikováno v:
Lipofuscin and Ceroid Pigments ISBN: 9781489953414
Mouse resident peritoneal macrophages (MPM) cultured with artificial lipoprotein consisting of cholesteryl linoleate complexed with bovine serum albumin (CL/BSA) rapidly accumulate ceroid in the form of rings. Experiments with various phenolic radica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aae9da7d444c7584c565794a782ed05
https://doi.org/10.1007/978-1-4899-5339-1_24
https://doi.org/10.1007/978-1-4899-5339-1_24