Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M J, McLaren"'
HRG4 (UNC119) mutation found in cone-rod dystrophy causes retinal degeneration in a transgenic model
Autor:
A, Kobayashi, T, Higashide, D, Hamasaki, S, Kubota, H, Sakuma, W, An, T, Fujimaki, M J, McLaren, R G, Weleber, G, Inana
Publikováno v:
Investigative ophthalmologyvisual science. 41(11)
To investigate the function and pathogenicity of HRG4, a photoreceptor synaptic protein homologous to the Caenorhabditis elegans neuroprotein UNC119.HRG4 was screened for mutations in patients with various retinopathies, and a transgenic mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::285d3aad27ae5210ee1243eb4eeaa8c4
https://pubmed.ncbi.nlm.nih.gov/11006213
https://pubmed.ncbi.nlm.nih.gov/11006213
Publikováno v:
Investigative ophthalmologyvisual science. 39(5)
To characterize further HRG4, a novel photoreceptor protein recently identified by subtractive cDNA cloning, by sequence analysis and immunolocalization.The rat homolog of HRG4, RRG4 was expressed and used to prepare an antibody. The antibody was use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d3fe2a2692a12fb7c1b41401a3c475e
https://pubmed.ncbi.nlm.nih.gov/9538874
https://pubmed.ncbi.nlm.nih.gov/9538874
Publikováno v:
Molecular and cellular biochemistry. 177(1-2)
Calreticulin is a major Ca2+ binding protein in the endoplasmic reticulum of non-muscle cells. In this report we show that calreticulin protein is strongly induced by heat shock. Activation and attenuation of the heat shock transcriptional response i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31aafb3ca502907baabe24794dad08fa
https://pubmed.ncbi.nlm.nih.gov/9450656
https://pubmed.ncbi.nlm.nih.gov/9450656
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 75(2)
We examined whether primary cultures of rat retinal pigment epithelial (RPE) cells and RPE cells of an immortalized rat cell line, BPEI-1, would be responsive to the neurokines ciliary neurotrophic factor (CNTF) and leukemia inhibitory factor (LIF),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e35e44002c1ab6cf971ab0e304f717d5
https://pubmed.ncbi.nlm.nih.gov/9250359
https://pubmed.ncbi.nlm.nih.gov/9250359
Autor:
M J, McLaren
Publikováno v:
Investigative ophthalmologyvisual science. 37(7)
To study phenotypic variation in primary cultures of rat retinal pigment epithelium (RPE) and to correlate cell morphology with rates of binding and ingestion of rod outer segments (ROS).Replicate cultures were prepared using RPE cell sheets isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03a28f9019121f16033d68095a53cf86
https://pubmed.ncbi.nlm.nih.gov/8641825
https://pubmed.ncbi.nlm.nih.gov/8641825
Publikováno v:
Investigative ophthalmologyvisual science. 34(2)
The goal of this study was to develop the first vital assay system for in vitro analysis of phagocytosis of rod outer segments (ROS) by normal retinal pigment epithelial (RPE) cells and for study of the phagocytic defect in RPE of the Royal College o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52a693e6d4a7f8fb21ad6bcc09fe2f0b
https://pubmed.ncbi.nlm.nih.gov/7680023
https://pubmed.ncbi.nlm.nih.gov/7680023
Publikováno v:
Pediatrics. 85(3)
Mitral valve prolapse has been studied extensively in the adult population, but less is known about it in children. Therefore, 813 children between 9 and 14 years of age were examined by a team of cardiologists and technicians. The children also resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ea175cf03a9e4724f6e288f1a9625ea
https://pubmed.ncbi.nlm.nih.gov/2304784
https://pubmed.ncbi.nlm.nih.gov/2304784
Autor:
Hendrik J. Koornhof, E Cohen, A S Lachman, John B. Barlow, M J McLaren, Kanarek Ks, D M Bramwell-Jones, J B Lakier, Douglas M. Hawkins, K R Bloom, G E Gale, W A Pocock
Publikováno v:
BMJ. 3:474-478
A survey to determine the prevalence of rheumatic heart disease (R.H.D.) in Black children was conducted in the creeches and primary schools of the South Western Townships of Johannesburg (Soweto). A total of 12 050 Black children were examined by 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4405d7b8b50eb3d3a8746d1c0a59668f
https://doi.org/10.1136/bmj.3.5981.474
https://doi.org/10.1136/bmj.3.5981.474
Publikováno v:
Heart. 41:554-558
A survey conducted by cardiologists in Soweto, Johannesburg, provided an opportunity of assessing the frequency of congenital heart disease in black schoolchildren. Among 12,050 schoolchildren aged 2 to 18 years, 48 had a congenital heart defect, yie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2081c7e844a757ab0fdc1ac2588e3caf
https://doi.org/10.1136/hrt.41.5.554
https://doi.org/10.1136/hrt.41.5.554
Publikováno v:
Heart. 43:67-73
Normal auscultatory findings were studied during a heart survey in which 12 050 Black schoolchildren, aged 2 to 18 years, were examined by cardiologists. Physiological third heart sounds were detected in 96 per cent of children, innocent systolic mur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977a0d1351148ca2bce6f6ba043c2082
https://doi.org/10.1136/hrt.43.1.67
https://doi.org/10.1136/hrt.43.1.67