Výsledky vyhledávání - "M J, McElrath"

OMIP‐064: A 27‐Color Flow Cytometry Panel to Detect and Characterize Human NK Cells and Other Innate Lymphoid Cell Subsets, MAIT Cells, and γδ T Cells

Autor: M J McElrath, Katharine V. Schwedhelm, Kenneth Stuart, Stephen C. De Rosa, Nina Hertoghs

Publikováno v: Cytometry A

This 27-color flow cytometry panel was developed in order to assess immunological changes over the course of an immunization and challenge regimen in two experimental malaria vaccine trials. The aim of the study was to find correlates of vaccine-indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633ca515ccdf6e24ad0a745280ec3ff5
https://doi.org/10.1002/cyto.a.24031

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Daily Vaginal Swabs and Mobile Phone Sex Report for Assessing HIV Virion Exposure Prospectively Among a Cohort of Young Sexually Active Women in South Africa (HVTN 915)

Autor: Abby Isaacs, Janan Dietrich, Joan Dragavon, Maria P. Lemos, John Hural, Reena K Gulati, M J McElrath, Erica Lazarus, Michele P. Andrasik, Doug Grove, Eva Chung, Robert W. Coombs, Glenda Gray, Adrian Puren, Cecilia Morgan, Fatima Laher, James G. Kublin, Yunda Huang

Publikováno v: J Acquir Immune Defic Syndr

Background Measurements of HIV exposure could help identify subpopulations at highest risk of acquisition and improve the design of HIV prevention efficacy trials and public health interventions. The HVTN 915 study evaluated the feasibility of self-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6803a7d4149fb6da67bb2321894e9565
https://doi.org/10.1097/qai.0000000000002015

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Increased Sequence Coverage through Combined Targeting of Variant and Conserved Epitopes Correlates with Control of HIV Replication

Autor: Jonathan M. Carlson, J. Sunshine, James I. Mullins, Stephen A. Migueles, David Heckerman, M J McElrath, Janine Maenza, Nicole Frahm, Julie Czartoski, Moon S. Kim

Publikováno v: Journal of Virology. 88:1354-1365

A major challenge in the development of an HIV vaccine is that of contending with the extensive sequence variability found in circulating viruses. Induction of HIV-specific T-cell responses targeting conserved regions and induction of HIV-specific T-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3397932daab538d04ec5cbf8fe1b64a3
https://doi.org/10.1128/jvi.02361-13

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Ontogeny and Specificities of Mucosal and Blood Human Immunodeficiency Virus Type 1-Specific CD8+Cytotoxic T Lymphocytes

Autor: A. Yuen, C. Galloway, John K. Lee, Keith R. Jerome, Luwy Musey, M J McElrath, Y. Ding, J. Cao

Publikováno v: Journal of Virology. 77:291-300

Induction of adaptive immunity to human immunodeficiency virus type 1 (HIV-1) at the mucosal site of transmission is poorly understood but crucial in devising strategies to control and prevent infection. To gain further understanding of HIV-1-specifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1dd50cb86a6647bab43f480f329a1a
https://doi.org/10.1128/jvi.77.1.291-300.2003

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A Phase II Study of Two HIV Type 1 Envelope Vaccines, Comparing Their Immunogenicity in Populations at Risk for Acquiring HIV Type 1 Infection

Autor: David C. Schwartz, T J Matthews, Geoffrey J. Gorse, Phillip W. Berman, Don Stablein, Anne Marie Duliege, Raphael Dolin, Mary S. Wolff, David C. Montefiori, Dani P. Bolognesi, M J McElrath, Peter F. Wright, Robert B. Belshe, Nzeera Ketter, Michael C. Keefer, Barney S. Graham, Fast P, Lawrence Corey, Donald P. Francis

Publikováno v: AIDS Research and Human Retroviruses. 16:907-919

Several immunogens induce HIV-specific neutralization and in vitro lymphoproliferation in adults at low HIV-1 risk, but responses in persons at high HIV-1 risk are not known. We performed a multicenter, double-blinded, adjuvant-controlled trial with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2f5b47289dd71342ab3d23faa88a6e7
https://doi.org/10.1089/08892220050042846

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Protection against Human Immunodeficiency Virus Type 1 Infection in Persons with Repeated Exposure: Evidence for T Cell Immunity in the Absence of Inherited CCR5 Coreceptor Defects

Autor: Lawrence Corey, J. Markee, Robert Akridge, Melissa R. Krone, Ann C. Collier, T. Karchmer, Michael Emerman, Luwy Musey, M J McElrath, W. C. Goh, M. Meldorf

Publikováno v: The Journal of Infectious Diseases. 179:548-557

It has been hypothesized that protection against human immunodeficiency virus (HIV)-1 infection may result from either acquired host immunity, inheritance of a dysfunctional CCR5 HIV-1 coreceptor, or a low or attenuated virus inoculum. Thirty-seven H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46322dbba919cd77c3148e664a8a736c
https://doi.org/10.1086/314632

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HIV-1MN Recombinant Glycoprotein 160 Vaccine-Induced Cellular and Humoral Immunity Boosted by HIV-1MN Recombinant Glycoprotein 120 Vaccine

Autor: Robert B. Belshe, T J Matthews, Martha M. Eibl, Lawrence Corey, M J McElrath, R H Hsieh, Mahendra Mandava, Geoffrey J. Gorse, Gira B. Patel, Mary Clare Walker, Phillip W. Berman

Publikováno v: AIDS Research and Human Retroviruses. 15:115-132

We evaluated prime-boost immunization with two recombinant envelope glycoprotein subunit vaccines (HIV-1MN recombinant gp160 vaccine in alum adjuvant [MN rgp160] and HIV-1MN recombinant gp120 vaccine in alum adjuvant [MN rgp120]) for safety and immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2428eabcc62c7bb7271e46e05c11c45
https://doi.org/10.1089/088922299311547

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Longitudinal Analysis of Quantitative Virologic Measures in Human Immunodeficiency Virus-Infected Subjects with >=400 CD4 Lymphocytes: Implications for Applying Measurements to Individual Patients

Autor: Lawrence Corey, D. Chernoff, James P. Hughes, F. Sinangil, Robert W. Coombs, Bryan R.G. Williams, M. C. Keefer, Lisa M. Demeter, M J McElrath, W. B. Paxton

Publikováno v: Journal of Infectious Diseases. 175:247-254

The natural variability of quantitative virologic measures among human immunodeficiency virus (HIV) type 1-infected persons was prospectively studied in 29 untreated persons with >600 CD4 cells/microL and in 15 persons receiving zidovudine monotherap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a8bba1cb657c2af1608dde337fdf1da
https://doi.org/10.1093/infdis/175.2.247

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Antagonism of vaccine-induced HIV-1-specific CD4+ T cells by primary HIV-1 infection: potential mechanism of vaccine failure

Autor: S J Kent, P D Greenberg, M C Hoffman, R E Akridge, M J McElrath

Publikováno v: The Journal of Immunology. 158:807-815

Prior immunity to HIV-1 elicited by vaccination may modify subsequent responses upon exposure to infectious HIV-1. An HIV-1-uninfected person entered in a vaccine trial that included immunizations to HIV-1(LAI) envelope with a recombinant vaccinia ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cdce83957054432a0e1900c944b7c9ba
https://doi.org/10.4049/jimmunol.158.2.807

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