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of 60
pro vyhledávání: '"M J, Mattes"'
Autor:
M. J. Mattes
Publikováno v:
Cancer Therapy with Radiolabeled Antibodies ISBN: 9781351070409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46360388f33dd2af85b267db7a0d547f
https://doi.org/10.1201/9781351070409-8
https://doi.org/10.1201/9781351070409-8
Autor:
M J Mattes
Publikováno v:
British Journal of Cancer
Much attention has been focused on the manner in which tumour cells die after treatment with cytotoxic agents. The basic question is whether cells die via apoptosis or via direct damage from the toxic agent. Various assays have been used to make this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe5a68ab2b009a7ccbaf689917e1577
http://europepmc.org/articles/PMC2360094
http://europepmc.org/articles/PMC2360094
Autor:
R B Michel, M J Mattes
Publikováno v:
British Journal of Cancer
Antibodies (Abs) to CD20 and MHC class II antigen were found to exhibit a novel processing pathway after binding to the surface of RL B-lymphoma cells. The Abs were ‘excreted’ as a part of large cytoplasmic fragments. These fragments formed at ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9f560b1341494f4d9252d2dc9fb1d6
https://doi.org/10.1038/sj.bjc.6602131
https://doi.org/10.1038/sj.bjc.6602131
Publikováno v:
Cancer Immunology, Immunotherapy. 49:208-216
The tumor-specific localization of an anti-CD74 Ab, LL1, was demonstrated in nude mice bearing xenografts of human B-cell lymphoma. This Ab, conjugated to radionuclides emitting Auger electrons, including 125I and 111In, was previously reported to ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4874912fe5eb890d411cf339a427c34
https://doi.org/10.1007/s002620000102
https://doi.org/10.1007/s002620000102
Publikováno v:
Immunology. 98:296-302
We previously described the processing of antibodies to CD74 (the major histocompatibility complex class II-associated invariant chain, Ii), by B-cell lymphoma cell lines. These cells expressed relatively low levels of Ii on the surface, but the mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1f980a74737437bf4b0d226f1b79df0
https://doi.org/10.1046/j.1365-2567.1999.00868.x
https://doi.org/10.1046/j.1365-2567.1999.00868.x
Autor:
Serengulam V. Govindan, David M. Goldenberg, Habibe Karacay, M. J. Mattes, Hans J. Hansen, Bill J. McBride, Gary L. Griffiths, Rhona Stein
Publikováno v:
Bioconjugate Chemistry. 10:231-240
The optimal use of radioiodinated internalizing monoclonal antibodies (mAbs) for radioimmunotherapy necessitates the development of practical methods for increasing the level of retention of 131I in the tumor. Lysosomally trapped ("residualizing") io
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f821fc0dd71faa0900a3cf9d9e88755
https://doi.org/10.1021/bc980075g
https://doi.org/10.1021/bc980075g
Autor:
M. J. Mattes, Habibe Karacay, Hans J. Hansen, G L Ong, Gary L. Griffiths, David M. Goldenberg
Publikováno v:
Nuclear Medicine Communications. 19:971-980
The catabolism of 99Tcm-antibody conjugates after internalization by B-cell lymphomas was investigated, using antibody LL1, an antibody to the MHC class II invariant chain which is internalized and catabolized very rapidly. Intact IgG antibodies were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29035c0f9527bccbffa6f6499ef18a4c
https://doi.org/10.1097/00006231-199810000-00007
https://doi.org/10.1097/00006231-199810000-00007
Publikováno v:
Cancer Immunology, Immunotherapy. 46:25-33
We reported previously that the blood clearance of injected mouse IgG2a was extremely rapid in many strains of nude and nu/+ mice. In an attempt to determine the cause of this phenomenon, the levels of endogenous IgG2a in the blood of these mice was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3222c66d6c74a4fb1e86d674fe64aff8
https://doi.org/10.1007/s002620050456
https://doi.org/10.1007/s002620050456
Autor:
Hans J. Hansen, Lisa B. Shih, David M. Goldenberg, Rosalyn D. Blumenthal, Robert M. Dunn, Malik E. Juweid, M. J. Mattes, Robert M. Sharkey, Rhona Stein, Gary L. Griffiths, T. M. Behr
Publikováno v:
Cancer Immunology, Immunotherapy. 44:179-188
LL2 is an anti-CD22 pan-B-cell monoclonal antibody which, when radiolabeled, has a high sensitivity for detecting B-cell, non-Hodgkin's lymphoma (NHL), as well as an antitumor efficacy in therapeutic applications. The aim of this study was to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63eedfe4d312ccb3246c4929dae73300
https://doi.org/10.1007/s002620050371
https://doi.org/10.1007/s002620050371
Publikováno v:
Immunological Investigations. 25:215-229
These experiments were performed to determine why rabbit complement lyses tumor cells very efficiently, while not having particularly strong activity in hemolytic assays or in any other complement assay. The target cells used were human tumor cells c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f3083126d18e33cf0ee01f4a6c518b
https://doi.org/10.3109/08820139609059304
https://doi.org/10.3109/08820139609059304