Zobrazeno 1 - 10
of 42
pro vyhledávání: '"M J, Lewin"'
Publikováno v:
Gut. 31:1242-1245
Clinical studies suggest that Helicobacter pylori may play a role in the pathogenesis of gastroduodenal ulcers in man but direct evidence of mucosal injury by this microorganism is still lacking. Paf-acether (paf) causes a number of disorders includi
Autor:
M, Buyse, M L, Ovesjö, H, Goïot, S, Guilmeau, G, Péranzi, L, Moizo, F, Walker, M J, Lewin, B, Meister, A, Bado
Publikováno v:
The European journal of neuroscience. 14(1)
Leptin, the product of the ob gene, plays a key role in the regulation of food intake via a cross-talk between hypothalamic leptin receptors and neuropeptides that affect feeding behaviour. Recent studies have shown a synergistic interaction between
Publikováno v:
Gastroenterologie clinique et biologique. 22(6-7)
Recent studies suggest that glycine-extended gastrin (G17-gly) stimulates in vitro proliferation of the pancreatic cell line AR4-2J, through selective receptors distinct from the CCK-B/G-receptor mediating the effects of amidated gastrin (G17). The a
Publikováno v:
Comptes rendus des seances de la Societe de biologie et de ses filiales. 192(2)
Matrix metalloproteinases (MMPs) and growth factors such as hepatocyte growth factor (HGF) are implicated in tumoral progression of several digestive cancers. The rat DHD/K12 colonic cancer cell line is very invasive in vivo. We showed by RT-PCR and
Publikováno v:
The American journal of gastroenterology. 92(2)
Cancers from patients with tumor-induced hypercalcemia usually produce a circulating factor that mimics the parathyroid hormone activity, termed parathyroid hormone-related protein. Incidence of tumor-induced hypercalcemia appears to be high in patie
Autor:
P, Jaïs, N, Kapel, D, Chosidow, N, Rupaire, P, Rougier, P, Lasser, M, Mignon, M J, Lewin, J G, Gobert
Publikováno v:
Gastroenterologie clinique et biologique. 21(10)
Mutations of TP53, a tumor suppressor gene, are found in 60% to 70% of colorectal cancers. These mutations usually induce an overexpression caused by modification of the p53 protein conformation. The aim of this study was to investigate whether stool
Publikováno v:
Gastroenterologie clinique et biologique. 20(5)
Hepatocyte growth factor (HGF) and its receptor c-Met exert mitogene and motogene activities in digestive tissues. The aim of the study was a) to detect and localize these proteins in adult human digestive mucosae, liver and pancreas, using western i
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(3)
We previously reported evidence for H3-receptor inhibition of cholinergic stimulation of acid secretion by isolated rabbit gastric glands. Because this inhibition was unsensitive to H2 antagonists, we postulated that the parietal cell should bear a H
Publikováno v:
Gastroenterologie clinique et biologique. 19(8-9)
The beta 3 adrenergic receptor stimulates lipolysis and colonic relaxation in the rat, and, suggestively, in man. Several human forms generated by different mRNA splicings can occur: the A form of 396 amino acids and the B and C forms extended by 12
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 316(11)
The heterodimer Ku, first described as a nuclear autoantigen, is a regulatory factor of DNA replication and transcription. We have expressed the p86 subunit of Ku in Escherichia coli as a fusion protein with glutathione-S-transferase, using the vecto