Zobrazeno 1 - 7
of 7
pro vyhledávání: '"M J, Kostura"'
Publikováno v:
The Journal of Immunology. 153:2592-2599
The major form of IL-1 beta-converting enzyme (ICE) identified in THP.1 monocytic cells and human monocytes is the 45-kDa precursor protein (p45), which is found in the cytoplasm. Cytoplasmic extracts of these cells show no pIL-1 beta cleavage activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69adc9b687c60f82edf1d6e477eac91f
https://doi.org/10.4049/jimmunol.153.6.2592
https://doi.org/10.4049/jimmunol.153.6.2592
Autor:
J Chin, M J Kostura
Publikováno v:
The Journal of Immunology. 151:5574-5585
Human blood monocytes synthesize but do not secrete IL-1 beta in response to low doses of bacterial cell-wall products. With this observation, we have developed a two-step staged release assay that separates IL-1 beta synthesis from secretion. This a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be0f3dd953707434797c9eb82ca4122d
https://doi.org/10.4049/jimmunol.151.10.5574
https://doi.org/10.4049/jimmunol.151.10.5574
Autor:
A D Howard, M J Kostura, N Thornberry, G J Ding, G Limjuco, J Weidner, J P Salley, K A Hogquist, D D Chaplin, R A Mumford
Publikováno v:
The Journal of Immunology. 147:2964-2969
IL-1 converting enzyme (ICE) specifically cleaves the human IL-1 beta precursor at two sequence-related sites: Asp27-Gly28 (site 1) and Asp116-Ala117 (site 2). Cleavage at Asp116-Ala117 results in the generation of mature, biologically active IL-1 be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9390c4ed3030b71f1af20259254e6195
https://doi.org/10.4049/jimmunol.147.9.2964
https://doi.org/10.4049/jimmunol.147.9.2964
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(6)
The major form of IL-1 beta-converting enzyme (ICE) identified in THP.1 monocytic cells and human monocytes is the 45-kDa precursor protein (p45), which is found in the cytoplasm. Cytoplasmic extracts of these cells show no pIL-1 beta cleavage activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b88f5aded17ef154d5b7fad53989ba3c
https://pubmed.ncbi.nlm.nih.gov/8077669
https://pubmed.ncbi.nlm.nih.gov/8077669
Autor:
J, Chin, M J, Kostura
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(10)
Human blood monocytes synthesize but do not secrete IL-1 beta in response to low doses of bacterial cell-wall products. With this observation, we have developed a two-step staged release assay that separates IL-1 beta synthesis from secretion. This a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd98ab6d1dd95575ba11ee0ead425837
https://pubmed.ncbi.nlm.nih.gov/8228247
https://pubmed.ncbi.nlm.nih.gov/8228247
Autor:
A D, Howard, M J, Kostura, N, Thornberry, G J, Ding, G, Limjuco, J, Weidner, J P, Salley, K A, Hogquist, D D, Chaplin, R A, Mumford
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 147(9)
IL-1 converting enzyme (ICE) specifically cleaves the human IL-1 beta precursor at two sequence-related sites: Asp27-Gly28 (site 1) and Asp116-Ala117 (site 2). Cleavage at Asp116-Ala117 results in the generation of mature, biologically active IL-1 be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::243c982d5aa6e32beadb185117ecfa53
https://pubmed.ncbi.nlm.nih.gov/1919001
https://pubmed.ncbi.nlm.nih.gov/1919001
Publikováno v:
Agents and actions. Supplements. 35
Interleukin-1 beta must be processed from its precursor form of 31.5 kDa to its mature form of 17 kDa in order to elaborate its wide array of bioactivities. The recent identification of a monocyte-specific endoprotease, termed interleukin-1 beta-conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb00d1c85ee8e8469c0c4b7ceb249a53
https://pubmed.ncbi.nlm.nih.gov/1781424
https://pubmed.ncbi.nlm.nih.gov/1781424