Zobrazeno 1 - 10
of 70
pro vyhledávání: '"M J, Khoury"'
Publikováno v:
Statistics in Medicine. 24:2299-2316
The impact of competing risks on tests of association between disease and haplotypes has been largely ignored. We consider situations in which linkage phase is ambiguous and show that tests for disease-haplotype association can lead to rejection of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e075462d06531c2238d56eabb26f0fc3
https://doi.org/10.1002/sim.2156
https://doi.org/10.1002/sim.2156
Autor:
Jan M. Friedman, Robert Clarke, W. D. Flanders, L Bailey, A Yesupriya, Quanhe Yang, T Liu, M. J. Khoury
Publikováno v:
The American journal of clinical nutrition. 95(5)
Background: The association between blood homocysteine concentration and the risk of cardiovascular disease (CVD) remains controversial, but few studies have examined the association between MTHFR C677T (a proxy for high homocysteine concentration) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed556ec9a7debade40bb5754c7204f13
http://ora.ox.ac.uk/objects/uuid:67922c6a-5bf6-4766-b7d3-4e1e768e61b1
http://ora.ox.ac.uk/objects/uuid:67922c6a-5bf6-4766-b7d3-4e1e768e61b1
Autor:
M L Martin, M J Khoury
Publikováno v:
Teratology. 46:267-270
A recent case report by Shepard et al. (Teratology 43:113-117, 1991) suggested that single ventricle may result from maternal cocaine ingestion by inducing coronary occlusion in the developing fetal heart. We used data from the Atlanta Birth Defects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883912457c544240f4261e9c0ef51b7b
https://doi.org/10.1002/tera.1420460310
https://doi.org/10.1002/tera.1420460310
Autor:
A, Rosano, L D, Botto, R S, Olney, M J, Khoury, A, Ritvanen, J, Goujard, C, Stoll, G, Cocchi, P, Merlob, O, Mutchinick, M C, Cornel, E E, Castilla, M L, Martínez-Frías, G, Zampino, J D, Erickson, P, Mastroiacovo
Publikováno v:
American journal of medical genetics. 93(2)
Although limb defects associated with other congenital anomalies are rarely studied, they may provide insights into limb development that may be useful for etiologic studies and public health monitoring. We pooled data from 11 birth defect registries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6efe34f8b1484c103e74da2113f2b838
https://pubmed.ncbi.nlm.nih.gov/10869112
https://pubmed.ncbi.nlm.nih.gov/10869112
Publikováno v:
Genetic epidemiology. 17
We applied the transmission/disequilibrium test (TDT) for sibs (S-TDT) and for families with one parent (1-TDT), to the Collaborative Study on the Genetics of Alcoholism data set. The combined test is used to screen the whole genome to locate genes r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5a0880541d1fc536343e0af0b29d1ec
https://pubmed.ncbi.nlm.nih.gov/10597459
https://pubmed.ncbi.nlm.nih.gov/10597459
Autor:
M J, Khoury
Publikováno v:
Teratology. 61(1-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60a14cabc48e2b67e06719c0935808e9
https://pubmed.ncbi.nlm.nih.gov/10603198
https://pubmed.ncbi.nlm.nih.gov/10603198
Publikováno v:
Genetic epidemiology. 17
We used a case-control design to scan the genome for any associations between genetic markers and disease susceptibility loci using the first two replicates of the Mycenaean population from the GAW11 (Problem 2) data. Using a case-control approach, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::944697cbc6a7961554d04b3c969fc233
https://pubmed.ncbi.nlm.nih.gov/10597530
https://pubmed.ncbi.nlm.nih.gov/10597530
Publikováno v:
American journal of preventive medicine. 16(2)
Breast cancer is the most common cancer and the second most common cause of cancer death among U.S. women. In 1998, about 178,700 new cases will be diagnosed and 43,500 women will die from the disease. Mutations in the BRCA1 gene, which was cloned in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a734ff382a4b88ee24cb7db487652ea
https://pubmed.ncbi.nlm.nih.gov/10343884
https://pubmed.ncbi.nlm.nih.gov/10343884
Publikováno v:
Epidemiology (Cambridge, Mass.). 10(2)
The case-only design is an efficient and valid approach to screening for gene-environment interaction under the assumption of the independence between exposure and genotype in the population. In this paper, we show that the case-only design is also a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7070ce64c8de03db0c086ff2fd965c8
https://pubmed.ncbi.nlm.nih.gov/10069253
https://pubmed.ncbi.nlm.nih.gov/10069253
Autor:
S B, Freeman, L F, Taft, K J, Dooley, K, Allran, S L, Sherman, T J, Hassold, M J, Khoury, D M, Saker
Publikováno v:
American journal of medical genetics. 80(3)
Mental retardation and hypotonia are found in virtually all Down syndrome (DS) individuals, whereas congenital heart defects (CHDs) are only present in a subset of cases. Although there have been numerous reports of the frequency of CHDs in DS, few o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bbf8261496e8ce8c430209df49f2be1
https://pubmed.ncbi.nlm.nih.gov/10533036
https://pubmed.ncbi.nlm.nih.gov/10533036