Zobrazeno 1 - 10
of 10
pro vyhledávání: '"M J, Hawkes"'
Autor:
Enrico Stefani, Juan Codina, L. Toro, F M Strickland, A M Spiegel, Atsuko Yatani, T Sawada, S C Froehner, Susan L. Hamilton, M. J. Hawkes
Publikováno v:
Journal of Biological Chemistry. 266:19528-19535
The alpha subunits of heterotrimeric GTP-binding (G) proteins act upon ion channels through both cytoplasmic and membrane-delimited pathways (Brown, A. M., and Birnbaumer, L. (1990) Annu. Rev. Physiol. 52, 197-213). The membrane pathway may involve e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4018348df961971805eaef79acbbd20
https://doi.org/10.1016/s0021-9258(18)55027-4
https://doi.org/10.1016/s0021-9258(18)55027-4
Autor:
Lutz Birnbaumer, Atsuko Yatani, Enrico Stefani, Juan Codina, Rafael Mattera, Y. Imoto, L. Toro, A. M. Brown, M. J. Hawkes, Susan L. Hamilton
Publikováno v:
Idiopathic Dilated Cardiomyopathy ISBN: 9783642778933
Our interest in calcium channels was prompted by the results of studies published by Hescheler and collaborators at the beginning of 1987, in which these authors showed in whole cell recordings that the inhibitory regulation of the voltage gate calci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ceac507bb8bef9d9928a16dd529bbc8
https://doi.org/10.1007/978-3-642-77891-9_22
https://doi.org/10.1007/978-3-642-77891-9_22
Publikováno v:
The Journal of biological chemistry. 267(10)
The defect in malignant hyperthermia (MH) alters the binding of [3H]ryanodine to the Ca(2+)-release channel by increasing its apparent affinity for the binding site. In sarcoplasmic reticulum (SR) membranes from both normal and mutant pigs the appare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d011bab0bc2bacbeacf1d87a11baac1f
https://pubmed.ncbi.nlm.nih.gov/1313019
https://pubmed.ncbi.nlm.nih.gov/1313019
Autor:
S L, Hamilton, J, Codina, M J, Hawkes, A, Yatani, T, Sawada, F M, Strickland, S C, Froehner, A M, Spiegel, L, Toro, E, Stefani
Publikováno v:
The Journal of biological chemistry. 266(29)
The alpha subunits of heterotrimeric GTP-binding (G) proteins act upon ion channels through both cytoplasmic and membrane-delimited pathways (Brown, A. M., and Birnbaumer, L. (1990) Annu. Rev. Physiol. 52, 197-213). The membrane pathway may involve e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26bc3099e2ea370d27ca732663843c08
https://pubmed.ncbi.nlm.nih.gov/1655789
https://pubmed.ncbi.nlm.nih.gov/1655789
Publikováno v:
Molecular pharmacology. 37(5)
In this paper, we study the modulation of the rabbit fast twitch skeletal muscle calcium release channel by assaying the kinetics of [3H]ryanodine binding, 45Ca2+ flux, and single-channel activity. The effects of modulators of the Ca2+ release channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9341bf02475e3b5bdbd8a0b123a93344
https://pubmed.ncbi.nlm.nih.gov/1692609
https://pubmed.ncbi.nlm.nih.gov/1692609
Publikováno v:
Biochemical Pharmacology. 36:4153-4161
In this paper, we describe the occurrence of both high and low affinity sites for dihydropyridines in crude membrane preparations from guinea pig ventricular tissue. The physiological significance of the low affinity site (apparent dissociation const
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed87cdc7fb35e157b048ad925b03a6ea
https://doi.org/10.1016/0006-2952(87)90574-0
https://doi.org/10.1016/0006-2952(87)90574-0
Autor:
M. J. Hawkes, A. P. Ginsberg
Publikováno v:
Inorganic Chemistry. 8:2189-2195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69a5e4a879d151bd24d38288522c3272
https://doi.org/10.1021/ic50080a033
https://doi.org/10.1021/ic50080a033
Publikováno v:
Membrane biochemistry. 8(3)
In this paper, we describe a simple and reproducible method for purifying large quantities of ryanodine receptor from skeletal muscle membranes. The procedure involves the use of ion exchange chromatography and sucrose gradient centrifugation to puri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c44aaf002a8c01e80e1d37a244c54b5
https://pubmed.ncbi.nlm.nih.gov/2641949
https://pubmed.ncbi.nlm.nih.gov/2641949
Publikováno v:
Molecular pharmacology. 31(4)
We correlated the binding of the dihydropyridines, nitrendipine and PN200-110, with their pharmacological actions on voltage-dependent membrane calcium channels. Binding was studied in clonal rat adrenal medullary cells (PC12) and in plasma membranes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c3fb46720006cd7edf55c0bb063efd6
https://pubmed.ncbi.nlm.nih.gov/2437436
https://pubmed.ncbi.nlm.nih.gov/2437436
Publikováno v:
Biochemistry. 28(19)
The dihydropyridine (DHP) receptor from rabbit skeletal muscle has been characterized by affinity labeling and purification. Two procedures were used for purification: one that was a procedure modified from that of Curtis and Catterall (1984) and one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6654c2da62708b9b4808ecb5d44969
https://pubmed.ncbi.nlm.nih.gov/2558713
https://pubmed.ncbi.nlm.nih.gov/2558713