Zobrazeno 1 - 10
of 98
pro vyhledávání: '"M J, Gething"'
Autor:
Tom P. Gordon, Catherine L. Keech, Anthony W. Purcell, T. A. Lynch, M. J. Gething, G. Kinoshita, A. Todd
Publikováno v:
Flinders University PURE
SUMMARYPatterns of autoantibody production are diagnostic of many autoimmune disorders; the recent observation of additional autospecificities towards stress-induced proteins may also provide insight into the mechanisms by which such responses arise.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c39a83577f0f33a84b1e393e9d30247
https://doi.org/10.1046/j.1365-2249.2003.02153.x
https://doi.org/10.1046/j.1365-2249.2003.02153.x
Publikováno v:
Thrombosis and Haemostasis. 71:124-128
SummaryPlatelet-rich clots are inefficiently lysed by current fibrinolytic agents. Platelets contain a great deal of plasminogen activator inhibitor 1 (PAI-1), the principal endogenous inhibitor of tissue-type plasminogen activator (t-PA). We have te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d24f1140dd649335b26856167ff61d8
https://doi.org/10.1055/s-0038-1642395
https://doi.org/10.1055/s-0038-1642395
Autor:
Willi K. Born, Douglas B. Young, E. Roman, M.-J. Gething, I. G. Haas, A. R. Coates, Rebecca L. O'Brien, P. Viitanen, W. J. Welch, P. Lund, C Moreno
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 339:363-368
Molecular chaperones belonging to heat shock protein families have been identified as prominent antigens in the immune response to a wide variety of infections. Recognition of such highly conserved antigens may contribute to protective immunity but,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446d78249013ff602dcae5e92fc29dcb
https://doi.org/10.1098/rstb.1993.0035
https://doi.org/10.1098/rstb.1993.0035
Publikováno v:
The EMBO Journal. 11:2583-2593
The KAR2 gene of Saccharomyces cerevisiae codes for an essential chaperone protein (BiP) that is localized in the lumen of the endoplasmic reticulum (ER). The high basal rate of transcription of KAR2 is increased transiently by heat shock: prolonged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddccfd6787942db25f81dfc65e4b6a98
https://doi.org/10.1002/j.1460-2075.1992.tb05323.x
https://doi.org/10.1002/j.1460-2075.1992.tb05323.x
Autor:
F, Wiradjaja, L M, Ooms, J C, Whisstock, B, McColl, L, Helfenbaum, J F, Sambrook, M J, Gething, C A, Mitchell
Publikováno v:
The Journal of biological chemistry. 276(10)
The budding yeast Saccharomyces cerevisiae has four inositol polyphosphate 5-phosphatase (5-phosphatase) genes, INP51, INP52, INP53, and INP54, all of which hydrolyze phosphatidylinositol (4,5)-bisphosphate. INP54 encodes a protein of 44 kDa which co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8ce9acfe10b9410fbb05424150b75c2
https://pubmed.ncbi.nlm.nih.gov/11116155
https://pubmed.ncbi.nlm.nih.gov/11116155
Publikováno v:
The Journal of biological chemistry. 274(42)
BiP, a resident endoplasmic reticulum member of the HSP70 family of molecular chaperones, associates transiently with a wide variety of newly synthesized exocytotic proteins. In addition to immunoglobulin heavy and light chains, the first natural sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a7934410fbdeb4107b72ada4e4b3a79
https://pubmed.ncbi.nlm.nih.gov/10514465
https://pubmed.ncbi.nlm.nih.gov/10514465
Publikováno v:
The Biochemical journal. 341
The lysosomal hydrolase N-acetylgalactosamine-4-sulphatase (4-sulphatase) is essential for the sequential degradation of the glycosaminoglycans, dermatan and chondroitin sulphate and, when deficient, causes the lysosomal storage disorder mucopolysacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d653cc7483e50ffdd9a5cabd8e7546c4
https://pubmed.ncbi.nlm.nih.gov/10377262
https://pubmed.ncbi.nlm.nih.gov/10377262
Autor:
D. Hartman, M. J. Gething
Publikováno v:
Stress-Inducible Cellular Responses ISBN: 9783034899017
A highly conserved protein folding machine has been maintained in the cytosol of both prokaryotic and eukaryotic organisms and in eukaryotic mitochondria. Homologous components of this machinery have also been identified in other organelles such as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26dd3a30764ceea56fc47177e92b2ed
https://doi.org/10.1007/978-3-0348-9088-5_2
https://doi.org/10.1007/978-3-0348-9088-5_2
Autor:
D, Hartman, M J, Gething
Publikováno v:
EXS. 77
A highly conserved protein folding machine has been maintained in the cytosol of both prokaryotic and eukaryotic organisms and in eukaryotic mitochondria. Homologous components of this machinery have also been identified in other organelles such as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87afd75db3d5c8b6d4fff1ff0ec222a3
https://pubmed.ncbi.nlm.nih.gov/8856966
https://pubmed.ncbi.nlm.nih.gov/8856966
Publikováno v:
The Journal of biological chemistry. 269(48)
We have studied the binding of synthetic peptides to three hsp70 molecular chaperones, DnaK, BiP, and hsc70, as a model for the interaction of hsp70 proteins with unfolded regions of target polypeptides. We measured the ability of 53 peptides to inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::480e4c5844616db7a06971a1338612f6
https://pubmed.ncbi.nlm.nih.gov/7982963
https://pubmed.ncbi.nlm.nih.gov/7982963