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Conformationally constrained butyrophenones with affinity for dopamine (D(1), D(2), D(4)) and serotonin (5-HT(2A), 5-HT(2B), 5-HT(2C)) receptors: synthesis of aminomethylbenzo[b]furanones and their evaluation as antipsychotics

Autor: E, Raviña, I, Casariego, C F, Masaguer, J A, Fontenla, G Y, Montenegro, M E, Rivas, M I, Loza, M J, Enguix, M, Villazon, M I, Cadavid, G C, Demontis

Publikováno v: Journal of medicinal chemistry. 43(24)

A series of novel conformationally restricted butyrophenones (6-aminomethyl-4,5,6,7-tetrahydrobenzo[b]furan-4-ones bearing 4-(6-fluorobenzisoxazolyl)piperidine, 4-(p-fluorobenzoyl)piperidine, 4-(o-methoxyphenyl)piperazine, 4-(2-pyridyl)piperazine, 4-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::827d41a68aa4f71725770af84303cc84
https://pubmed.ncbi.nlm.nih.gov/11101359

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