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Cystic fibrosis HRCT scores correlate strongly with Pseudomonas infection

Autor: Terry E, Robinson, Ann N, Leung, Xiaorong, Chen, Richard B, Moss, M J, Emond

Publikováno v: Pediatric pulmonology. 44(11)

In order to establish a valid surrogate outcome measure, it must be shown that the outcome measure (chest HRCT scores in cystic fibrosis [CF] patients) demonstrates strong statistical association with established endpoints of disease, such as Pseudom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf26704bbe14168eac1eb6d999091a88
https://pubmed.ncbi.nlm.nih.gov/19824046

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Chromosomal changes in a dedifferentiated chondrosarcoma: a case report and review of the literature

Autor: D P, O'Malley, K E, Opheim, T S, Barry, D B, Chapman, M J, Emond, E U, Conrad, T H, Norwood

Publikováno v: Cancer genetics and cytogenetics. 124(2)

The chromosome abnormalities observed in a dedifferentiated chondrosarcoma are reported. A new molecular cytogenetic technique, spectral karyotyping, was used to identify and confirm structural rearrangements in this case. A review of the literature

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ad1b2929a3bfec68a5cc548fc3bbf201
https://pubmed.ncbi.nlm.nih.gov/11172900

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Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes

Autor: M J, Moser, W L, Bigbee, S G, Grant, M J, Emond, R G, Langlois, R H, Jensen, J, Oshima, R J, Monnat

Publikováno v: Cancer research. 60(9)

Werner syndrome (WRN) is an uncommon autosomal recessive disease in which progeroid features are associated with genetic instability and an elevated risk of neoplasia. We have used the glycophorin A (GPA) somatic cell mutation assay to analyze geneti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::85c5c1a3a48b9b3addfe3df1a27114db
https://pubmed.ncbi.nlm.nih.gov/10811130

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Pancolonic chromosomal instability precedes dysplasia and cancer in ulcerative colitis

Autor: P S, Rabinovitch, S, Dziadon, T A, Brentnall, M J, Emond, D A, Crispin, R C, Haggitt, M P, Bronner

Publikováno v: Cancer research. 59(20)

Patients with long-standing ulcerative colitis (UC) are at increased risk for colon cancer. These cancers are thought to arise from preexisting dysplasia in a field of abnormal cells that often exhibits aneuploidy and p53 abnormalities. Using dual co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2be83df269939e306c52614d37829e53
https://pubmed.ncbi.nlm.nih.gov/10537290

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Quantitative study of the variability of hepatic iron concentrations

Autor: M J, Emond, M P, Bronner, T H, Carlson, M, Lin, R F, Labbe, K V, Kowdley

Publikováno v: Clinical chemistry. 45(3)

The hepatic iron concentration (HIC) is widely used in clinical practice and in research; however, data on the variability of HIC among biopsy sites are limited. One aim of the present study was to determine the variability of HIC within both healthy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3b472c854d184d604e462aea1853096e
https://pubmed.ncbi.nlm.nih.gov/10053034

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Detection of optic disc changes with Glaucoma-Scope probability maps

Autor: N, Yamada, M J, Emond, R P, Mills, M M, Leen, P P, Chen, D C, Stanford

Publikováno v: Journal of glaucoma. 7(6)

To test whether a statistical method using a probability map could detect true changes in optic disc topography.The average of three Glaucoma-Scope images (Ophthalmic Imaging Systems were used for analysis at each of two sessions. A Glaucoma-Scope pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::402d023687c9a72ea2769ab3cf24d31d
https://pubmed.ncbi.nlm.nih.gov/9871859

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I-PpoI and I-CreI homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment

Autor: G M, Argast, K M, Stephens, M J, Emond, R J, Monnat

Publikováno v: Journal of molecular biology. 280(3)

Plasmid libraries containing partially randomized cleavage sites for the eukaryotic homing endonucleases I-PpoI and I-CreI were constructed, and sites that could be cleaved by I-PpoI or I-CreI were selectively recovered by successive cycles of cleava

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c6832c54a0eec84fa4672b75ca898b0a
https://pubmed.ncbi.nlm.nih.gov/9665841

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Plasma vitamin K1 level is decreased in primary biliary cirrhosis

Autor: K V, Kowdley, M J, Emond, J A, Sadowski, M M, Kaplan

Publikováno v: The American journal of gastroenterology. 92(11)

To measure directly plasma vitamin K1 in patients with primary biliary cirrhosis (PBC) and to examine the relationship between vitamin K1 level, prothrombin time, other fat-soluble vitamin levels, and severity of cholestasis.We directly measured leve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3c75d296e8158a3744686b8d6e6ff7ff
https://pubmed.ncbi.nlm.nih.gov/9362192

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Probability maps of sequential glaucoma-scope images help identify significant change

Autor: N, Yamada, R P, Mills, M M, Leen, M J, Emond, A C, Reynolds, D C, Stanford

Publikováno v: Journal of glaucoma. 6(5)

The purpose of this study was to identify areas of the optic disc showing high variability of repeated depth measurements, and to minimize the effect of baseline variability in interpretation of possible change over time using the Glaucoma-Scope.Seve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bbb082c9ef282087df42177ab62eabd3
https://pubmed.ncbi.nlm.nih.gov/9327345

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