Zobrazeno 1 - 10
of 19
pro vyhledávání: '"M J, Elms"'
Publikováno v:
Blood Coagulation & Fibrinolysis. 5:227-232
Most commercial D-dimer enzyme immunoassays employ two antibodies, a fibrin specific capture monoclonal and a less specific antibody cross-reacting with epitopes present on fibrinogen. Two different ELISA systems were compared to test whether this cr
Publikováno v:
Thorax. 45:684-687
Plasma concentrations of cross linked fibrin degradation products, a marker of intravascular thrombosis and fibrinolysis, were measured in 495 patients with suspected pulmonary embolism referred for ventilation-perfusion lung scanning to determine wh
Publikováno v:
Thrombosis Research. 58:273-281
A new system for the detection of fibrin degradation products in whole blood has been developed. The test provides a clearly visible agglutination of the patient's red blood cells in the presence of elevated levels of the crosslinked fibrin derivativ
Autor:
D, Rylatt, K, Wilson, B E, Kemp, M J, Elms, B, Manickavasagam, W, Shi, A, Cox, M J, McArthur, J, O'Hara, M E, Corbett
Publikováno v:
Progress in clinical and biological research. 392
A rapid whole blood agglutination test has been developed for the detection of endotoxin. The test reagent consists of polymyxin B (PmB) conjugated to the Fab fragment of the anti-glycophorin antibody 1C3/86. After addition of reagent to whole blood,
Autor:
M J, Elms, P G, Bundesen, D, Rowbury, S, Goodall, N, Wakeham, J A, Rowell, C J, Hillyard, D B, Rylatt
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 4(1)
Automated assays for the measurement of cross-linked fibrin derivatives in plasma (XL-FbDP) have been developed utilizing latex beads coated with anti-D dimer monoclonal antibody (DD-3B6/22) for both the Cobas Fara Chemistry Centrifugal and the Cobas
Publikováno v:
Fibrinolysis. 10:17
Measurement of cross linked fibrin derivatives in plasma: an immunoassay using monoclonal antibodies
Publikováno v:
Journal of Clinical Pathology. 37:882-887
Fibrinogen degradation, fibrin polymerisation, and the insertion of cross links into fibrin by fibrin stabilising factor lead to the appearance of new antigenic determinants. Antibodies against these antigenic sites may react specifically with the de
Publikováno v:
American Journal of Clinical Pathology. 89:347-352
The results are reported of a clinical and laboratory evaluation of the use of a random-access centrifugal analyzer linked to a personal computer in the management of the routine workload of a hemostasis laboratory. Over a three-month period, prothro
Publikováno v:
Thrombosis and Haemostasis. 50:591-594
SummaryWe have prepared a monoclonal antibody which recognises an antigenic determinant on D dimer, a specific fragment resulting from the degradation of crosslinked fibrin. This antibody has been used in the development of an enzyme-linked immunoass
Autor:
D. Wyatt, Paul P. Masci, D.B. Rylatt, A.S. Blake, I H Bunce, A.N. Whitaker, M J Elms, W.A. Fletcher, D.A. Massingham, P.G. Bundesen, L.E. Cottis, A.J. Webber
Publikováno v:
Thrombosis Research. 31:767-778
Monoclonal antibodies (MAb) were raised against human D dimer. The hybridomas were screened with a solid phase enzyme immunoassay against D dimer and fibrinogen degradation products. Among the panel of MAb identified, two distinct patterns emerged; t