Výsledky vyhledávání - "M J, Breslin"

In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate

Autor: T, Prueksaritanont, L M, Gorham, M J, Breslin, J H, Hutchinson, G D, Hartman, K P, Vyas, T A, Baillie

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 25(8)

The present study demonstrates the utility of an in vitro-in vivo correlative approach in the selection of an optimum prodrug candidate of L-767,679 (N-([7-(piperazin-1-yl)-3,4-dihydro-1(1H)-isoquinolinone-2-yl]acetyl)-3(S)-(ethynyl)-beta-alanine), a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f498549b2c4a50b0c5276eef59ac263d
https://pubmed.ncbi.nlm.nih.gov/9280406

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