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Abnormal lymphatic phenotype in a CRISPR mouse model of the human lymphedema-causing Connexin47 R260C point mutation

Autor: D J, Mustacich, R I, Kylat, M J, Bernas, R J, Myles, J A, Jones, J D, Kanady, A M, Simon, T G, Georgieva, M H, Witte, R P, Erickson, P W, Pires

Publikováno v: Lymphology. 54(2)

Connexin proteins form gap junctions controlling exchange of ions and small molecules between cells and play an important role in movement of lymph within lymphatic vessels. Connexin47 (CX47) is highly expressed in lymphatic endothelial cells and CX4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f61b25456adf58a6b843ad12493b4d28
https://pubmed.ncbi.nlm.nih.gov/34735753

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EVOLUTION OF THE 2020 INTERNATIONAL SOCIETY OF LYMPHOLOGY CONSENSUS DOCUMENT PARALLELS ADVANCES IN LYMPHOLOGY: AN HISTORICAL PERSPECTIVE

Autor: M H, Witte, M J, Bernas

Publikováno v: Lymphology. 53(1)

[Editorial] Evolution of the 2020 international society of lymphology consensus document parallels advances in lymphology: An historical perspective.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b70c9c6de1643fd6d7458fa09e319389
https://pubmed.ncbi.nlm.nih.gov/32521125

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Whole-body lymphangioscintigraphy and SPECT/CT in children with lymphatic complications after surgery for complex congenital heart disease

Autor: P H, Kuo, B J, Barber, R I, Kylat, S E, Klewer, S, Behan, S, Lau-Braunhut, M J, Bernas, L, Moedano, A D, Bedrick, D J, Mustacich, M H, Witte

Publikováno v: Lymphology. 52(4)

The number of patients surviving repair of complex congenital heart disease (CCHD) has increased due to improved surgical techniques, post operative management and outpatient care. Likewise, this growing patient population has demonstrated an increas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d8bd618ec5a0f44ee577e6d424a2e52
https://pubmed.ncbi.nlm.nih.gov/32171182

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Lymphatic route of transport and pharmacokinetics of Micrurus fulvius (coral snake) venom in sheep

Autor: D, Paniagua, L, Jiménez, C, Romero, I, Vergara, A, Calderón, M, Benard, M J, Bernas, H, Rilo, A, de Roodt, G, D' Suze, M H, Witte, L, Boyer, A, Alagón

Publikováno v: Lymphology. 45(4)

The contribution of the lymphatic system to the absorption and systemic bioavailability of Micrurus fulvius venom after subcutaneous (SC) administration was assessed using a central lymph-cannulated sheep model. Micrurus fulvius venom was administere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37939b400a2982b674269f5e4dd93580
https://pubmed.ncbi.nlm.nih.gov/23700761

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Novel FOXC2 missense mutation identified in patient with lymphedema-distichiasis syndrome and review

Autor: M T, Dellinger, K, Thome, M J, Bernas, R P, Erickson, M H, Witte

Publikováno v: Lymphology. 41(3)

Lymphedema-distichiasis (OMIM 153400) is a dominantly inherited disorder typically presenting with lymphedema at puberty and distichiasis at birth. The condition has been decisively linked to mutations in the forkhead transcription factor FOXC2 which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea771fcf1897e00d31654df965303c10
https://pubmed.ncbi.nlm.nih.gov/19013876

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Segregation analyses and a genome-wide linkage search confirm genetic heterogeneity and suggest oligogenic inheritance in some Milroy congenital primary lymphedema families

Autor: C J, Holberg, R P, Erickson, M J, Bernas, M H, Witte, K E, Fultz, M, Andrade, C L, Witte

Publikováno v: American journal of medical genetics. 98(4)

We previously described six families with Milroy congenital lymphedema, only one of which showed possible linkage to a candidate locus on chromosome 5 [Witte et al., 1998]. We have now performed a complex segregation analysis of these families, and p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7cf82490873e6369cb6a28299f1b89a8
https://pubmed.ncbi.nlm.nih.gov/11170072

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Endothelial transdifferentiated phenotype and cell-cycle kinetics of AIDS-associated Kaposi sarcoma cells

Autor: D L, Way, M H, Witte, M, Fiala, G, Ramirez, R B, Nagle, M J, Bernas, M, Dictor, P, Borgs, C L, Witte

Publikováno v: Lymphology. 26(2)

The nature of Kaposi sarcoma (KS) (vascular malignancy vs. discordant angiogenesis) and lineage of the progenitor cell remain unclear. Therefore, AIDS-KS enzyme isolate cultures were prepared from excised skin lesions. Endothelial marker positivity f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6c15bc6e0a79955d0a94c1a5246ed320
https://pubmed.ncbi.nlm.nih.gov/8355521

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