Zobrazeno 1 - 10
of 379
pro vyhledávání: '"M Iyengar"'
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Post-diagnosis weight gain is common in early-stage breast cancer and is associated with increased risk of recurrence and mortality. Intentional weight loss is difficult to maintain, and digital lifestyle interventions may provide a scalable
Externí odkaz:
https://doaj.org/article/abd07bc9cf244605a99255e93c692aa1
Autor:
Gayane Hovsepyan, Ana Barac, Theodore M. Brasky, Aladdin H. Shadyab, Amy Lehman, Eric M. McLaughlin, Nazmus Saquib, Neil M. Iyengar, Robert A. Wild, Bette J. Caan, Pinkal Desai, Jennifer Beebe Dimmer, Cynthia A. Thomson, Michael S. Simon
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 16626-16636 (2023)
Abstract Background Published studies have demonstrated inconclusive relationships between serum lipid levels and mortality after cancer. Methods The primary objective was to evaluate the relationship between fasting lipid levels and mortality after
Externí odkaz:
https://doaj.org/article/fd9f3afcb6aa4359842ca4e88257a11a
Autor:
Byuri Angela Cho, Neil M. Iyengar, Xi Kathy Zhou, Hillary Mendieta, Lisle Winston, Domenick J. Falcone, Jonathan Landa, Monica Morrow, Andrew J. Dannenberg
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Increased trunk fat is associated with an elevated risk of breast cancer in normal-weight postmenopausal women. The main objective of this study was to determine whether levels of trunk fat are associated with changes in breast gene expressi
Externí odkaz:
https://doaj.org/article/c63d8480c8eb44f9a03c8671284995de
Autor:
Suhasini M. Iyengar, Kelly K. Barnsley, Hoang Yen Vu, Ian Jef A. Bongalonta, Alyssa S. Herrod, Jasmine A. Scott, Mary Jo Ondrechen
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Three protein targets from SARS-CoV-2, the viral pathogen that causes COVID-19, are studied: the main protease, the 2′-O-RNA methyltransferase, and the nucleocapsid (N) protein. For the main protease, the nucleophilicity of the catalytic cysteine C
Externí odkaz:
https://doaj.org/article/c18e19af907a4599b50246390d08c0cd
Autor:
Neil M. Iyengar, Xi Kathy Zhou, Hillary Mendieta, Omar El-Hely, Dilip D. Giri, Lisle Winston, Domenick J. Falcone, Hanhan Wang, Lingsong Meng, Taehoon Ha, Michael Pollak, Monica Morrow, Andrew J. Dannenberg
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Obesity is associated with an increased risk of breast cancer in post-menopausal women and decreased risk in pre-menopausal women. Conversely, in BRCA1/2 mutation carriers, pre-menopausal obesity is associated with early-onset breast cancer.
Externí odkaz:
https://doaj.org/article/9bc77085a3d541aca6d6d81c076de591
Autor:
Sherry Shen, Neil M. Iyengar
Publikováno v:
Nutrients, Vol 14, Iss 17, p 3542 (2022)
Hyperinsulinemia is an independent risk factor for cancer mortality. Insulin-lowering dietary strategies such as calorie restriction (CR), low-carbohydrate or ketogenic diets (KD), and intermittent fasting (IF) are aimed at reducing systemic stores o
Externí odkaz:
https://doaj.org/article/3c0cf2b270bd451b9a39b434f53d4573
Publikováno v:
Cancer Research. 83:OT2-17
Background: The prognosis for advanced/metastatic triple negative breast cancer (TNBC) remains poor and novel therapeutic strategies are urgently needed to improve outcomes. Insulin resistance and obesity contribute to cancer progression and are inde
Autor:
Bethina Liu, Sherry Shen, Erica Salehi, Yuan Chen, Nicolas Toumbacaris, Johnny Allsop, Cara Anselmo, Stacie Corcoran, Bridget Kelly, Rocco Magnoli, Andrea Smith, Melissa Emerzian, Julia Brockway-Marchello, Doreen Bacotti, Mark E. Robson, Neil M. Iyengar
Publikováno v:
Cancer Research. 83:P5-08
Background: Diet is a modifiable risk factor for breast cancer risk and mortality. Current guidelines recommend a diet that provides a diverse array of nutrients, comprised predominantly of fruits/vegetables and whole grains, with limited added sugar
Autor:
Gengyang, Yuan, Maeva, Dhaynaut, Nicolas J, Guehl, Sepideh, Afshar, Dalena, Huynh, Sung-Hyun, Moon, Suhasini M, Iyengar, Manish Kumar, Jain, Julie E, Pickett, Hye Jin, Kang, Mary Jo, Ondrechen, Georges, El Fakhri, Marc D, Normandin, Anna-Liisa, Brownell
Publikováno v:
Journal of medicinal chemistry. 65(14)
An array of triazolopyridines based on JNJ-46356479 (
Autor:
Urvi A. Shah, Francesca Castro, Aishwarya Anuraj, Eliana Schach, Andriy Derkach, Nisha S. Joseph, Peter A. Adintori, Laura Guttentag, Jenna Blaslov, Justin R. Cross, Kylee H. Maclachlan, Sham Mailankody, Neha Korde, Carlyn Tan, Malin Hultcrantz, Hani Hassoun, Oscar B. Lahoud, Gunjan L. Shah, Michael Scordo, Jonathan U. Peled, David J. Chung, Heather Landau, Jun J. Mao, Neil M. Iyengar, Saad Usmani, Sergio A. Giralt, Marcel R.M. van den Brink, Alexander M. Lesokhin
Publikováno v:
Blood. 140:5052-5055