Enhanced expression of hexokinase I in pancreatic islets induced by sucrose administration

Autor: H Del Zotto, María Laura Massa, Bárbara Maiztegui, J. J. Gagliardino, M I Borelli

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

Administration of a sucrose-rich diet (SRD) to normal amsters induces an insulin-resistant state and a significant increase of insulin secretion and β-cell mass. Islets isolated from these animals had a marked increase in glucose metabolism and gluc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a85071d1a0060e95825302d3fe9213f
https://doi.org/10.1677/joe.1.06662

Glucose-induced secretion of ACTH-like products by rat pancreatic islets

Autor: Juan José Gagliardino, M I Borelli, Maria I. Morano, F. E. Estivariz

Publikováno v: Archives Internationales de Physiologie, de Biochimie et de Biophysique. 102:17-20

This work was performed to study the release of proopiomelanocortin (POMC)-derived peptides from isolated pancreatic islets and the effect of ACTH--a member of that peptide family--on insulin secretion. Islets were incubated with 3,3 and 16.6 mM gluc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f454f76be3c9a185405568244e263dc
https://doi.org/10.3109/13813459408996100

Islet adaptive changes to fructose-induced insulin resistance: β-cell mass, glucokinase, glucose metabolism, and insulin secretion

Autor: H Del Zotto, Juan José Gagliardino, M I Borelli, M. A. Raschia, Bárbara Maiztegui

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

β-Cell mass, hexokinase/glucokinase (HK/GK) activity, glucose metabolism and insulin secretion were studied in the islets of rats with fructose-induced insulin resistance (IR). Normal male Wistar rats were fed a standard commercial diet and water wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b202630de3fc96236ded9eef2cf9bb0c
http://sedici.unlp.edu.ar/handle/10915/82723

Pancreatic duodenal homeobox-1 and islet neogenesis-associated protein: a possible combined marker of activateable pancreatic cell precursors

Autor: L Massa, H Del Zotto, Juan José Gagliardino, M I Borelli, Luis Emilio Flores

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

The aim of this work was to study the possible relationship between pancreatic duodenal homeobox-1 (Pdx-1) and islet neogenesis-associated protein (INGAP) during induced islet neogenesis. Pregnant hamsters were fed with (S) and without (C) sucrose, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb52e7e3c3622a73296c797bcb2dc1d
https://pubmed.ncbi.nlm.nih.gov/12740013

Changes induced by sucrose administration on glucose metabolism in pancreatic islets in normal hamsters

Autor: H Del Zotto, J. J. Gagliardino, M I Borelli, María Laura Massa

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

We correlated the changes in glucose-induced insulin secretion with those observed in glucose metabolism and hexokinase/glucokinase activity in islets from normal sucrose-fed hamsters. Blood glucose and insulin levels were measured in normal male ham

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b591cf369a4e53e492e7c4dde0b4a4
https://pubmed.ncbi.nlm.nih.gov/11739021