Zobrazeno 1 - 10
of 20
pro vyhledávání: '"M I, Steinberg"'
Publikováno v:
ChemInform. 26
Publikováno v:
Cardiovascular drugs and therapy. 14(1)
The use of positive inotropic agents, such as sympathomimetics and phosphodiesterase inhibitors, in heart failure (HF) is limited by proarrhythmic and positive chronotropic effects. In the present study, we compared the hemodynamic effects of intrave
Publikováno v:
Diabetes. 48(5)
We studied the effect of moxonidine, an imidazoline ligand, on metabolic and hemodynamic parameters in Zucker diabetic fatty rats, a model of type 2 diabetes. In one group (metabolic group), 8-week-old rats were started on a diet containing either mo
Autor:
Z H, Zhang, M I, Steinberg
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 274(1)
LY 97241 [(LY), p-nitro tertiary amine analog of clofilium] has been shown to prolong action potential duration in vitro but its effects on transient outward potassium current (Ito) are unknown. The authors investigated the effect of LY on Ito in rat
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 256(1)
Pinacidil, a potassium channel opener (PCO), relaxes vascular smooth muscle by increasing potassium ion membrane conductance, thereby causing membrane hyperpolarization. PCOs also act on cardiac muscle to decrease action potential duration (APD) sele
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 342:726-726
Publikováno v:
Journal of Food Science. 41:57-61
A beverage consisting of water, whole soybeans (including hulls), sugar and flavor has been developed. Preparation includes soaking and then blanching the whole soybeans in 0.5% sodium bicarbonate, grinding with water in a hammermih, heating the slur
Publikováno v:
Clinical and Experimental Hypertension. Part A: Theory and Practice. 7:1481-1497
We used microsphere techniques to determine cardiac output and tissue blood flows in chloralose-anesthetized spontaneously hypertensive rats treated with LY127210 (10 mg/kg, i.p.), hydralazine (2 mg/kg, i.p.), or saline. LY127210 decreased blood pres
Publikováno v:
Experimental Biology and Medicine. 148:1141-1145
SummaryThe effect of the calcium ion-ophore A23187 on contractility in guinea pig left atria was studied. This ionophore increased both the force of contraction and the rate of tension development in a concentration dependent manner. The positive ino
Autor:
R. L. Volle, M. I. Steinberg
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 272:16-31
The actions of d-tubocurarine, lobeline and nicotine were studied at the end-plate region of frog sartorius muscle fibers bathed in Frog-Ringer solution containing 12 mM MgCl2. End-plate potentials (EPPs) evoked by stimulation of the sciatic nerve we