Výsledky vyhledávání - "M I, Colnaghi"

Biochemical Characterization of Trop-2, a Cell Surface Molecule Expressed by Human Carcinomas: Formal Proof that the Monoclonal Antibodies T16 and MOv-16 Recognize Trop-2

Autor: M I Colnaghi, Silvia Miotti, Saverio Alberti, S Menard, Mara Fornaro, M Stella, C E Klein

Publikováno v: Scopus-Elsevier

Trop-2 is a cell surface structure recognized by the 162-46.2 mAb and expressed by most human carcinomas. Since the 162-46.2 mAb works poorly in immunoprecipitation, to characterize the structure of Trop-2 we searched for other mAbs directed against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83ded8f599add7bec9602669925c09a
https://doi.org/10.1089/hyb.1992.11.539

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Production and characterization of monoclonal antibodies directed against the laminin receptor precursor

Autor: S. BUTO', C. GHIRELLI, P. AIELLO, E. TAGLIABUE, E. ARDINI, A. MAGNIFICO, M. E. SOBEL, M. I. COLNAGHI AND S. MENARD, MONTUORI, NUNZIA

The 67-kDa laminin receptor (67LR) is an important tumor marker whose molecular structure has not yet been fully elucidated. To shed new light on this molecule, we raised a series of eight new monoclonal antibodies, designated MPLR1 to 8, directed ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::952196f2a46f3e42c2e86fc41f226385
http://hdl.handle.net/11588/150874

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Expression profile of saccharide epitope CaMBr1 in normal and neoplastic tissue from dogs, cats, and rats: implication for the development of human-derived cancer vaccines

Autor: E, Adobati, A, Zacchetti, M E, Perico, F, Cremonesi, G, Rasi, P S, Vallebona, M, Hagenaars, P J, Kuppen, I, Pastan, L, Panza, G, Russo, M I, Colnaghi, S, Canevari

Publikováno v: The Histochemical journal. 31(11)

CaMBr1 is a blood group-related tumour-associated antigen, whose pattern of expression provides a therapeutic window for passive or active immunotherapy and points to the promise of a vaccine against carcinomas overexpressing this antigen. In this co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0bd759a35f06dbf03bb5e15f8a2d7cd4
https://pubmed.ncbi.nlm.nih.gov/10646838

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Correlation between tumor vascularity, vascular endothelial growth factor production by tumor cells, serum vascular endothelial growth factor levels, and serum angiogenic activity in patients with breast carcinoma

Autor: A, Balsari, J A, Maier, M I, Colnaghi, S, Ménard

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 79(7)

Angiogenesis is an important prognostic factor in invasive breast carcinoma. We analyzed sera and tumor samples from 36 patients with primary breast carcinomas to determine the relationship between tumor vascularity, vascular endothelial growth facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1367267558c80460d181b2b6a9d45efa
https://pubmed.ncbi.nlm.nih.gov/10418830

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Level of anti-mouse-antibody response induced by bi-specific monoclonal antibody OC/TR in ovarian-carcinoma patients is associated with longer survival

Autor: S, Miotti, D R, Negri, O, Valota, M, Calabrese, R L, Bolhuis, J W, Gratama, M I, Colnaghi, S, Canevari

Publikováno v: International journal of cancer. 84(1)

More than 60% of cancer patients injected with intact murine monoclonal antibody (MAb) develop a humoral response against the antigen even after a single dose. Analysis of a series of 35 ovarian-cancer patients entered in phase-I and -II clinical stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72df6cea51dd08cde76db837067729ad
https://pubmed.ncbi.nlm.nih.gov/9988234

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Evaluation of the balance between angiogenic and antiangiogenic circulating factors in patients with breast and gastrointestinal cancers

Autor: D, Morelli, D, Lazzerini, S, Cazzaniga, P, Squicciarini, P, Bignami, J A, Maier, L, Sfondrini, S, Ménard, M I, Colnaghi, A, Balsari

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 4(5)

Angiogenesis is a critical determinant of tumor growth. Tumor cells produce or induce angiogenic molecules that act specifically on endothelial cells (ECs) but also release angiostatic molecules. Thus, tumor angiogenesis represents a net balance betw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05a9c7370e0360e435f05ac6afdbc2bc
https://pubmed.ncbi.nlm.nih.gov/9607580

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Tumor pretargeting: role of avidin/streptavidin on monoclonal antibody internalization

Autor: P, Casalini, E, Luison, S, Ménard, M I, Colnaghi, G, Paganelli, S, Canevari

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(9)

Radioimmunodetection of tumor can be improved by introducing a two-step system in which radiolabeled streptavidin is administrated after the injection of a biotinylated monoclonal antibody (MAb) (two-step) or radiolabeled biotin is injected after bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::947a058487401f1e49d9067ae5776871
https://pubmed.ncbi.nlm.nih.gov/9293791

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Inhibition of tumorigenicity in lung adenocarcinoma cells by c-erbB-2 antisense expression

Autor: P, Casalini, S, Ménard, S M, Malandrin, C M, Rigo, M I, Colnaghi, C M, Cultraro, S, Segal

Publikováno v: International journal of cancer. 72(4)

The lung carcinoma cell line Calu3, which overexpresses the c-erbB-2 oncogene, was stably transfected with antisense (AS) cDNA constructs encompassing different regions of the c-erbB-2 gene. Transfected cells were analyzed for their tumorigenic prope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eae241d68798a800dbde1c85931cfa1a
https://pubmed.ncbi.nlm.nih.gov/9259403

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Lymphoid infiltration as a prognostic variable for early-onset breast carcinomas

Autor: S, Ménard, G, Tomasic, P, Casalini, A, Balsari, S, Pilotti, N, Cascinelli, B, Salvadori, M I, Colnaghi, F, Rilke

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 3(5)

Infiltration by lymphoid cells is a common feature of many human tumors, including breast carcinomas, and the degree of infiltration has been suggested to be a measure of the host immune response. Our analyses in a series of 1919 cases of primary duc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a6fecc64ecb6a1fe16eff187bc22d44
https://pubmed.ncbi.nlm.nih.gov/9815754

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