Zobrazeno 1 - 10
of 23
pro vyhledávání: '"M Huttinger"'
Autor:
Zachary M. Huttinger, Laura M. Haynes, Andrew Yee, Colin A. Kretz, Matthew L. Holding, David R. Siemieniak, Daniel A. Lawrence, David Ginsburg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The serine protease inhibitor (SERPIN) plasminogen activator inhibitor-1 (PAI-1) is a key regulator of the fibrinolytic system, inhibiting the serine proteases tissue- and urokinase-type plasminogen activator (tPA and uPA, respectively). Mis
Externí odkaz:
https://doaj.org/article/f47950a71a2243e4bed673bbf54e9f40
Autor:
Laura M. Haynes, Zachary M. Huttinger, Andrew Yee, Colin A. Kretz, David R. Siemieniak, Daniel A. Lawrence, David Ginsburg
Plasminogen activator inhibitor-1 (PAI-1), a member of the serine protease inhibitor (SERPIN) superfamily of proteins, is unique among SERPINs for exhibiting a spontaneous conformational change to a latent or inactive state. The functional half-life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7da8a4cae23d0fa26f3c436ba8ad59de
https://doi.org/10.1101/2022.07.19.500671
https://doi.org/10.1101/2022.07.19.500671
Autor:
Chandler J. Rygalski, Zachary M. Huttinger, Songzhu Zhao, Guy Brock, Kyle VanKoevering, Matthew O. Old, Theodoros N. Teknos, James W. Rocco, Sidharth V. Puram, Nolan B. Seim, Brian Swendseid, Catherine T. Haring, Antoine Eskander, Stephen Y. Kang
Publikováno v:
Oral Oncology. 138:106333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a14c5b60cf539e666c4f2cc8fbfe6512
https://doi.org/10.1016/j.oraloncology.2023.106333
https://doi.org/10.1016/j.oraloncology.2023.106333
Publikováno v:
The American surgeon. 88(4)
Only 0.12% to 2% of diagnosed hernias are Spigelian type. Even less frequently encountered—Grynfeltt-Lesshaft hernias—hernias have unknown incidence. A Spigelian hernia is encountered along the Spigelian fascia and Grynfeltt-Lesshaft hernias are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e01cbc5092c76f451c8f8d7eefec90
https://pubmed.ncbi.nlm.nih.gov/34784778
https://pubmed.ncbi.nlm.nih.gov/34784778
Autor:
Laura M. Haynes, Zachary M. Huttinger, Andrew Yee, Colin A. Kretz, David R. Siemieniak, Daniel A. Lawrence, David Ginsburg
Publikováno v:
Journal of Biological Chemistry. 298:102608
Plasminogen activator inhibitor-1 (PAI-1), a member of the serine protease inhibitor superfamily of proteins, is unique among serine protease inhibitors for exhibiting a spontaneous conformational change to a latent or inactive state. The functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee7a6a92edfd5eefb592633a147fc24
https://doi.org/10.1016/j.jbc.2022.102608
https://doi.org/10.1016/j.jbc.2022.102608
Autor:
David R. Siemieniak, Andrew Yee, Laura M. Haynes, Daniel A. Lawrence, David Ginsburg, Matthew L Holding, Zachary M Huttinger, Colin A. Kretz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
The serine protease inhibitor (SERPIN) plasminogen activator inhibitor-1 (PAI-1) is a key regulator of the fibrinolytic system, inhibiting the serine proteases tissue- and urokinase-type plasminogen activator (tPA and uPA, respectively). Missense var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a9da89b60b96afdc166b8a55ca1130
https://doi.org/10.1038/s41598-021-97871-7
https://doi.org/10.1038/s41598-021-97871-7
Autor:
Ryan M. Huttinger, Elizabeth M. Sawyer
Publikováno v:
The American Surgeon. :000313482110385
An 8-year-old male presented for evaluation of symptoms consistent with appendicitis. Upon laparoscopy, the patient was found to have appendicitis with a concomitant Amyand hernia. The latter pathology highlights a rare presentation of inguinal herni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8943ddc88350618e802a27edac4035a
https://doi.org/10.1177/00031348211038583
https://doi.org/10.1177/00031348211038583
Autor:
Harry L. T. Mobley, Zachary M Huttinger, Sara N. Smith, Ursula Waack, David Ginsburg, Ayush Kumar, Daniel A. Lawrence, Andrew Yee, Alban Deroux, Mark Warnock, Maria Sandkvist
Publikováno v:
mBio
mBio, Vol 9, Iss 6 (2018)
mBio, Vol 9, Iss 6, p e01606-18 (2018)
mBio, Vol 9, Iss 6 (2018)
mBio, Vol 9, Iss 6, p e01606-18 (2018)
Ventilator-associated pneumonia and catheter-related bacteremia are the most common and severe infections caused by Acinetobacter baumannii. Besides the capsule, lipopolysaccharides, and the outer membrane porin OmpA, little is known about the contri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12d68331dd94118e9f3692c90a6eec5
https://doi.org/10.1128/mbio.01606-18
https://doi.org/10.1128/mbio.01606-18
Autor:
Ryan M. Huttinger, Simon C. Robson, Adam Reynolds, Debra G Wheeler, Richard J. Gumina, Katherine Stanfill, Tatiana Novitskaya, Elena Chepurko, Karen M. Dwyer, Roman Covarrubias, Peter J. Cowan, Zachary M. Huttinger
Objective— Circulating blood cells and endothelial cells express ectonucleoside triphosphate diphosphohydrolase-1 (CD39) and ecto-5′-nucleotidase (CD73). CD39 hydrolyzes extracellular ATP or ADP to AMP. CD73 hydrolyzes AMP to adenosine. The goal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c0e589d3aee316ad2c1f0dabef0487
https://europepmc.org/articles/PMC5206760/
https://europepmc.org/articles/PMC5206760/
Autor:
Bo Zhang, Tatiana Novitskaya, Debra G Wheeler, Yan Ru Su, Cristi L. Galindo, Heng He, Zhaobin Xu, Frank E. Harrell, Yanna Song, Dan M. Roden, Quinn S. Wells, Mark T. Ziolo, Tarek S. Absi, Richard J. Gumina, Elena Chepurko, Ryan M. Huttinger, Saradhadevi Varadharaj, Christian M. Shaffer, Jay L. Zweier, Mark J. Kohr, Meng Xu
Background— Despite increased secondary cardiovascular events in patients with ischemic cardiomyopathy (ICM), the expression of innate cardiac protective molecules in the hearts of patients with ICM is incompletely characterized. Therefore, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b168999927cad3b6409a2a0c428e88e
https://europepmc.org/articles/PMC5319711/
https://europepmc.org/articles/PMC5319711/