Zobrazeno 1 - 10
of 696
pro vyhledávání: '"M Huston"'
Autor:
Carlos E. Bravo-Iñiguez, Jason R. Fritz, Shilpa Shukla, Susmita Sarangi, Dane A. Thompson, Seema G. Amin, Tea Tsaava, Saher Chaudhry, Sara P. Valentino, Hannah B. Hoffman, Catherine W. Imossi, Meghan E. Addorisio, Sergio I. Valdes-Ferrer, Sangeeta S. Chavan, Lionel Blanc, Christopher J. Czura, Kevin J. Tracey, Jared M. Huston
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Deficiency of coagulation factor VIII in hemophilia A disrupts clotting and prolongs bleeding. While the current mainstay of therapy is infusion of factor VIII concentrates, inhibitor antibodies often render these ineffective. Because precli
Externí odkaz:
https://doaj.org/article/067fc7beffb44e5298ec3b3aee8105af
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/fe2a652920924983ba181c01f12477c5
Publikováno v:
Molecules, Vol 29, Iss 7, p 1519 (2024)
4-Chloroisocoumarin compounds have broad inhibitory properties against serine proteases. Here, we show that selected 3-alkoxy-4-chloroisocoumarins preferentially inhibit the activity of the conserved serine protease High-temperature requirement A of
Externí odkaz:
https://doaj.org/article/087dead06bba4958a977c9e0321c54cb
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Chlamydia trachomatis is a strict intracellular human pathogen. It is the main bacterial cause of sexually transmitted infections and the etiologic agent of trachoma, which is the leading cause of preventable blindness. Despite over 100 years since C
Externí odkaz:
https://doaj.org/article/8ddfbb5f0b164f81a242856490382b19
Autor:
Wilhelmina M. Huston, Amba Lawrence, Bryan A. Wee, Mark Thomas, Peter Timms, Lenka A. Vodstrcil, Anna McNulty, Ruthy McIvor, Karen Worthington, Basil Donovan, Samuel Phillips, Marcus Y. Chen, Christopher K. Fairley, Jane S. Hocking
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
Chlamydia trachomatis, the most common bacterial sexually transmitted infection worldwide, is responsible for considerable health burden due to its significant sequelae. There are growing concerns about chlamydial treatment and management due to wide
Externí odkaz:
https://doaj.org/article/04faf6529dec426982a6acb894439c43
Autor:
Christopher J. Czura, Marom Bikson, Leigh Charvet, Jiande D. Z. Chen, Manfred Franke, Marat Fudim, Eric Grigsby, Sam Hamner, Jared M. Huston, Navid Khodaparast, Elliot Krames, Bruce J. Simon, Peter Staats, Kristl Vonck
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Since the outbreak of the COVID-19 pandemic, races across academia and industry have been initiated to identify and develop disease modifying or preventative therapeutic strategies has been initiated. The primary focus has been on pharmacological tre
Externí odkaz:
https://doaj.org/article/975128b7da69449695ee2f8cc2cc2c63
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Dual RNA-seq experiments examining viral and bacterial pathogens are increasing, but vary considerably in their experimental designs, such as infection rates and RNA depletion methods. Here, we have applied dual RNA-seq to Chlamydia trachoma
Externí odkaz:
https://doaj.org/article/fe8a5218d62e4a1f995962750e59e982
Publikováno v:
Microbiology Australia, Vol 42, Iss 2, Pp 65-68 (2021)
The human cervicovaginal microbiome has an important role in the health and homoeostasis of the female reproductive tract. A eubiotic microbiome is typically dominated with lactic acid producing bacteria and is categorised into five community state t
Externí odkaz:
https://doaj.org/article/67ebb884d92f4766bca0db225a253bf0
Autor:
Regan J. Hayward, James W. Marsh, Michael S. Humphrys, Wilhelmina M. Huston, Garry S. A. Myers
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Chlamydia are Gram-negative, obligate intracellular bacterial pathogens responsible for a broad spectrum of human and animal diseases. In humans, Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection worldwide
Externí odkaz:
https://doaj.org/article/8dd81036c68840eb8c3d1b87a86c6fe2
Autor:
Helen Bittleston, Jane S. Hocking, Jane L. Goller, Jacqueline Coombe, Deborah Bateson, Sally Sweeney, Kirsteen Fleming, Wilhelmina M. Huston
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Introduction There is currently no test for pelvic inflammatory disease (PID) that is non-invasive and sufficiently sensitive and specific. Clinicians must therefore diagnose PID clinically, ruling out medical emergencies and conducting pelvic examin
Externí odkaz:
https://doaj.org/article/e6f6e556b5a24b60a2b6ee9d5cf9f850