Zobrazeno 1 - 10
of 87
pro vyhledávání: '"M Hourihan"'
Autor:
Collin Yvès Ewald, John M Hourihan, Monet S Bland, Carolin Obieglo, Iskra Katic, Lorenza E Moronetti Mazzeo, Joy Alcedo, T Keith Blackwell, Nancy E Hynes
Publikováno v:
eLife, Vol 6 (2017)
Transient increases in mitochondrially-derived reactive oxygen species (ROS) activate an adaptive stress response to promote longevity. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases produce ROS locally in response to various stimuli, a
Externí odkaz:
https://doaj.org/article/c1ca8a9498f44db89692e81e2c75f37a
Autor:
Michael J Steinbaugh, Sri Devi Narasimhan, Stacey Robida-Stubbs, Lorenza E Moronetti Mazzeo, Jonathan M Dreyfuss, John M Hourihan, Prashant Raghavan, Theresa N Operaña, Reza Esmaillie, T Keith Blackwell
Publikováno v:
eLife, Vol 4 (2015)
In Caenorhabditis elegans, ablation of germline stem cells (GSCs) extends lifespan, but also increases fat accumulation and alters lipid metabolism, raising the intriguing question of how these effects might be related. Here, we show that a lack of G
Externí odkaz:
https://doaj.org/article/8931817616d244b3a07b0f3600bc78a3
Akademický článek
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Autor:
John M. Hourihan, Lorenza E Moronetti Mazzeo, T. Keith Blackwell, L. Paulette Fernández-Cárdenas
Publikováno v:
Molecular Cell. 63:553-566
Summary Emerging evidence suggests that many proteins may be regulated through cysteine modification, but the extent and functions of this signaling remain largely unclear. The endoplasmic reticulum (ER) transmembrane protein IRE-1 maintains ER homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e2b087ac00b82c80f1fa782eb8d586
https://doi.org/10.1016/j.molcel.2016.07.019
https://doi.org/10.1016/j.molcel.2016.07.019
Cells and organisms face constant exposure to reactive oxygen species (ROS), either from the environment or as a by-product from internal metabolic processes. To prevent cellular damage from ROS, cells have evolved detoxification mechanisms. The acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e243accfca9646d39d9ef6deee4ac7
https://europepmc.org/articles/PMC5809133/
https://europepmc.org/articles/PMC5809133/
Autor:
John M. Hourihan, T. Keith Blackwell, Carolin Obieglo, Collin Y. Ewald, Nancy E. Hynes, Joy Alcedo, Iskra Katic, Lorenza E Moronetti Mazzeo, Monet S Bland
Publikováno v:
eLife, Vol 6 (2017)
eLife, 6
eLife, 6
Transient increases in mitochondrially-derived reactive oxygen species (ROS) activate an adaptive stress response to promote longevity. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases produce ROS locally in response to various stimuli, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1286b3b77c6c2e342f2d1b8051f3ab77
https://doi.org/10.7554/elife.19493
https://doi.org/10.7554/elife.19493
Autor:
Collin Yvès, Ewald, John M, Hourihan, Monet S, Bland, Carolin, Obieglo, Iskra, Katic, Lorenza E, Moronetti Mazzeo, Joy, Alcedo, T Keith, Blackwell, Nancy E, Hynes
Publikováno v:
eLife
Transient increases in mitochondrially-derived reactive oxygen species (ROS) activate an adaptive stress response to promote longevity. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases produce ROS locally in response to various stimuli, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6180c427477a6c6e41105f3b8a8af98e
https://pubmed.ncbi.nlm.nih.gov/28085666
https://pubmed.ncbi.nlm.nih.gov/28085666
Autor:
John M. Hourihan, Theresa N Operaña, Lorenza E Moronetti Mazzeo, Jonathan M. Dreyfuss, T. Keith Blackwell, Reza Esmaillie, Prashant Raghavan, Stacey Robida-Stubbs, Sri Devi Narasimhan, Michael J. Steinbaugh
Publikováno v:
eLife
eLife, Vol 4 (2015)
eLife, Vol 4 (2015)
In Caenorhabditis elegans, ablation of germline stem cells (GSCs) extends lifespan, but also increases fat accumulation and alters lipid metabolism, raising the intriguing question of how these effects might be related. Here, we show that a lack of G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185bcafc29f2b6a764aa67927db2b4fc
http://europepmc.org/articles/PMC4541496
http://europepmc.org/articles/PMC4541496
Autor:
Lorenza E Moronetti Mazzeo, Michael J. Steinbaugh, Stacey Robida-Stubbs, Theresa N Operaña, John M. Hourihan, T. Keith Blackwell, Prashant Raghavan, Reza Esmaillie, Jonathan M. Dreyfuss, Sri Devi Narasimhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a84c269bc2e4adf7bda035887063b0c
https://doi.org/10.7554/elife.07836.042
https://doi.org/10.7554/elife.07836.042
Publikováno v:
Antioxidantsredox signaling. 19(5)
The signaling molecule hydrogen sulfide (H2S) protects cells against oxidative stress and activates NF-E2 p45-related factor 2 (Nrf2), a transcription factor that regulates antioxidant genes. We sought to establish whether H2S requires Nrf2 to protec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f90a7adfe281293f6502da07b48f20
https://pubmed.ncbi.nlm.nih.gov/23145493
https://pubmed.ncbi.nlm.nih.gov/23145493